Tryptophan

indoleamine 2,3-dioxygenase 1 ; Homo sapiens







1003 Article(s)
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1 34269660 Tryptophan Metabolism in Atherosclerosis and Diabetes. 2022 2
2 34752953 Indoleamine 2,3-dioxygenase 1 (IDO1) inhibitors and PROTAC-based degraders for cancer therapy. 2022 Jan 5 4
3 34859884 Indoleamine 2,3-dioxygenase (IDO)-1 and IDO-2 activity and severe course of COVID-19. 2022 Mar 1
4 35045867 Single-nucleotide polymorphisms and activities of indoleamine 2,3-dioxygenase isoforms, IDO1 and IDO2, in tuberculosis patients. 2022 Jan 19 2
5 35051612 Indoleamine dioxygenase and tryptophan dioxygenase activities are regulated through GAPDH- and Hsp90-dependent control of their heme levels. 2022 Feb 20 1
6 35057467 Tryptophan Metabolism Is Associated with BMI and Adipose Tissue Mass and Linked to Metabolic Disease in Pediatric Obesity. 2022 Jan 11 3
7 35085834 Role of indoleamine 2,3-dioxygenase 1 (IDO1) and kynurenine pathway in the regulation of the aging process. 2022 Mar 2
8 35150740 Inhibition of the Na+/K+-ATPase by cardiac glycosides suppresses expression of the IDO1 immune checkpoint in cancer cells by reducing STAT1 activation. 2022 Mar 1
9 35173722 Targeting Tryptophan Catabolism in Cancer Immunotherapy Era: Challenges and Perspectives. 2022 2
10 35187162 T Lymphocyte Infiltration in Association with IDO1 Expression in Resected Lung Adenocarcinoma and Normal Adjacent Lung Tissues. 2022 2
11 35203299 Hypothesis: Emerging Roles for Aryl Hydrocarbon Receptor in Orchestrating CoV-2-Related Inflammation. 2022 Feb 13 4
12 35226872 Brugia malayi Microfilariae Induce Autophagy through an Interferon-γ Dependent Mechanism on Human Monocytes. 2022 Feb 28 2
13 35244712 Inhibitory effect of ascorbate on tryptophan 2,3-dioxygenase. 2022 May 27 4
14 35245456 Kynurenine importation by SLC7A11 propagates anti-ferroptotic signaling. 2022 Mar 3 2
15 35264796 Tryptophan depletion results in tryptophan-to-phenylalanine substitutants. 2022 Mar 2
16 35294258 Metabolic adaptation of ovarian tumors in patients treated with an IDO1 inhibitor constrains antitumor immune responses. 2022 Mar 16 2
17 35358772 Discovery and biological evaluation of tanshinone derivatives as potent dual inhibitors of indoleamine 2, 3-dioxygenase 1 and tryptophan 2, 3-dioxygenase. 2022 May 5 4
18 35371054 Indoleamine 2, 3-Dioxygenase 1 Mediates Survival Signals in Chronic Lymphocytic Leukemia via Kynurenine/Aryl Hydrocarbon Receptor-Mediated MCL1 Modulation. 2022 4
19 35413710 The Role of Kynurenines Produced by Indolamine-2,3-Dioxygenase 1 in Sepsis. 2022 Apr 12 2
20 35422466 The tryptophan catabolite or kynurenine pathway in schizophrenia: meta-analysis reveals dissociations between central, serum, and plasma compartments. 2022 Apr 14 2
21 35435494 Effects of dietary tryptophan supplementation on body temperature, hormone, and cytokine levels in broilers exposed to acute heat stress. 2022 Apr 18 1
22 35456119 Increased Indoleamine 2,3-Dioxygenase 1 (IDO-1) Activity and Inflammatory Responses during Chikungunya Virus Infection. 2022 Apr 7 3
23 35458704 Curcumin Facilitates Aryl Hydrocarbon Receptor Activation to Ameliorate Inflammatory Astrogliosis. 2022 Apr 13 2
24 35466092 Proposed Pathway Linking Respiratory Infections with Depression. 2022 May 31 3
25 35493480 Impact of IDO1 and IDO2 on the B Cell Immune Response. 2022 1
26 35502977 Mechanism Found for IDO1 Inhibitor Evasion. 2022 May 3 1
27 35510301 Extracellular adenosine triphosphate induces IDO and IFNγ expression of human periodontal ligament cells through P2 X7 receptor signaling. 2022 May 4 1
28 35545044 A pan-cancer metabolic atlas of the tumor microenvironment. 2022 May 10 1
29 35582948 Indoleamine 2,3-Dioxygenase 1 Deletion-Mediated Kynurenine Insufficiency in Vascular Smooth Muscle Cells Exacerbates Arterial Calcification. 2022 Jun 14 1
30 35604497 Elevated serum levels of kynurenine pathway metabolites in patients with Behçet disease. 2022 Jun 4
31 32707579 Resistance Exercise Modulates Kynurenine Pathway in Pancreatic Cancer Patients. 2021 Jan 1
32 32794357 Tryptophan-kynurenine ratio as a biomarker of bladder cancer. 2021 Apr 2
33 32974990 Characterization of Apo-Form Selective Inhibition of Indoleamine 2,3-Dioxygenase*. 2021 Feb 2 4
34 33025106 Increased immunosuppression impairs tissue homeostasis with aging and age-related diseases. 2021 Jan 2
35 33040382 Mycobacterium leprae induces a tolerogenic profile in monocyte-derived dendritic cells via TLR2 induction of IDO. 2021 Jul 1
36 33222028 The evaluation of serum tryptophan and kynurenine levels in patients with obstructive sleep apnea syndrome. 2021 Sep 5
37 33243840 Decreased IDO1-dependent tryptophan metabolism in aged lung during influenza. 2021 May 1
38 33298590 Preclinical Characterization of Linrodostat Mesylate, a Novel, Potent, and Selective Oral Indoleamine 2,3-Dioxygenase 1 Inhibitor. 2021 Mar 1
39 33328638 Anti-tumour immunity induces aberrant peptide presentation in melanoma. 2021 Feb 3
40 33333163 Discovery and optimization of substituted oxalamides as novel heme-displacing IDO1 inhibitors. 2021 Feb 1 1
41 33346015 Activation and deactivation steps in the tryptophan breakdown pathway in major depressive disorder: A link to the monocyte inflammatory state of patients. 2021 Apr 20 1
42 33373218 Conformational Plasticity in Human Heme-Based Dioxygenases. 2021 Feb 3 4
43 33390854 The IFN-γ-IDO1-kynureine pathway-induced autophagy in cervical cancer cell promotes phagocytosis of macrophage. 2021 1
44 33410234 Tryptophan 2,3-dioxygenase in tumor cells is associated with resistance to immunotherapy in renal cell carcinoma. 2021 Mar 2
45 33418116 Tryptophan and indole metabolism in immune regulation. 2021 Jun 2
46 33422134 Inflammatory cytokines-stimulated human muscle stem cells ameliorate ulcerative colitis via the IDO-TSG6 axis. 2021 Jan 9 1
47 33422142 Metabolic phenotyping reveals a reduction in the bioavailability of serotonin and kynurenine pathway metabolites in both the urine and serum of individuals living with Alzheimer's disease. 2021 Jan 9 1
48 33427761 Regulation of vascular tone and blood pressure by singlet molecular oxygen in inflammation. 2021 Mar 1 4
49 33460767 Role of tryptophan metabolism in cancers and therapeutic implications. 2021 Mar 3
50 33539022 Indoleamine 2,3-Dioxygenase Activity-Induced Acceleration of Tumor Growth, and Protein Kinases-Related Novel Therapeutics Regimens. 2021 4