Sirolimus

Target of rapamycin ; Drosophila melanogaster







29 Article(s)
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1 35175796 Lysosomal cystine mobilization shapes the response of TORC1 and tissue growth to fasting. 2022 Feb 18 1
2 33761878 Mitochondrial genotype alters the impact of rapamycin on the transcriptional response to nutrients in Drosophila. 2021 Mar 24 1
3 33763414 Light Stimuli and Circadian Clock Affect Neural Development in Drosophila melanogaster. 2021 1
4 33978540 V-ATPase controls tumor growth and autophagy in a Drosophila model of gliomagenesis. 2021 Dec 1
5 34065203 Genotype and Trait Specific Responses to Rapamycin Intake in Drosophila melanogaster. 2021 May 20 2
6 34571738 Thermal and Oxygen Flight Sensitivity in Ageing Drosophila melanogaster Flies: Links to Rapamycin-Induced Cell Size Changes. 2021 Sep 2 1
7 31959630 Von Hippel-Lindau tumor suppressor (VHL) stimulates TOR signaling by interacting with phosphoinositide 3-kinase (PI3K). 2020 Feb 21 1
8 31995752 EGFR Signaling Stimulates Autophagy to Regulate Stem Cell Maintenance and Lipid Homeostasis in the Drosophila Testis. 2020 Jan 28 1
9 32097403 Snail synchronizes endocycling in a TOR-dependent manner to coordinate entry and escape from endoreplication pausing during the Drosophila critical weight checkpoint. 2020 Feb 1
10 32339661 Mating status affects Drosophila lifespan, metabolism and antioxidant system. 2020 Aug 1
11 32666649 Aging shifts mitochondrial dynamics toward fission to promote germline stem cell loss. 2020 Aug 1
12 30368647 Ferulic Acid Produced by Lactobacillus fermentum Influences Developmental Growth Through a dTOR-Mediated Mechanism. 2019 Jan 2
13 27909242 Beneficial effects of rapamycin in a Drosophila model for hereditary spastic paraplegia. 2017 Jan 15 1
14 27741510 Rapamycin enhances survival in a Drosophila model of mitochondrial disease. 2016 Dec 6 2
15 26158631 TORC1 Inhibition by Rapamycin Promotes Antioxidant Defences in a Drosophila Model of Friedreich's Ataxia. 2015 2
16 24842780 Forkhead, a new cross regulator of metabolism and innate immunity downstream of TOR in Drosophila. 2014 Oct 1
17 25512509 TORC1 regulators Iml1/GATOR1 and GATOR2 control meiotic entry and oocyte development in Drosophila. 2014 Dec 30 1
18 22173033 Synergism between altered cortical polarity and the PI3K/TOR pathway in the suppression of tumour growth. 2012 Feb 1 1
19 22863314 Drosophila TRPML is required for TORC1 activation. 2012 Sep 11 1
20 23132575 Freeze-dried royal jelly maintains its developmental and physiological bioactivity in Drosophila melanogaster. 2012 1
21 20017609 Pharmacological inhibition of phosphoinositide 3 and TOR kinases improves survival of Drosophila melanogaster. 2010 Apr-Jun 1
22 20160148 Mammalian target of rapamycin signaling and autophagy: roles in lymphangioleiomyomatosis therapy. 2010 Feb 1
23 20573703 TSC1/2 tumour suppressor complex maintains Drosophila germline stem cells by preventing differentiation. 2010 Aug 1 1
24 19684592 Rapamycin activation of 4E-BP prevents parkinsonian dopaminergic neuron loss. 2009 Sep 1
25 19720874 TOR-mediated autophagy regulates cell death in Drosophila neurodegenerative disease. 2009 Sep 7 1
26 16713952 Functional genomics identifies TOR-regulated genes that control growth and division. 2006 May 23 1
27 16785324 TOR coordinates bulk and targeted endocytosis in the Drosophila melanogaster fat body to regulate cell growth. 2006 Jun 19 1
28 15245566 Insulin reduces apoptosis and increases DNA synthesis and cell size via distinct signalling pathways in Drosophila Kc cells. 2004 Aug 2
29 12893813 Drosophila Rheb GTPase is required for cell cycle progression and cell growth. 2003 Sep 1 1