methyl n-(4"-(9-acridinylamino)-3-methoxy-phenyl) methane sulfonamide

DNA topoisomerase II beta ; Homo sapiens







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1 16239602 Mutation P732L in human DNA topoisomerase IIbeta abolishes DNA cleavage in the presence of calcium and confers drug resistance. 2006 Jan 1
2 15322234 Mutation E522K in human DNA topoisomerase IIbeta confers resistance to methyl N-(4'-(9-acridinylamino)-phenyl)carbamate hydrochloride and methyl N-(4'-(9-acridinylamino)-3-methoxy-phenyl) methane sulfonamide but hypersensitivity to etoposide. 2004 Sep 1