Phorbol Esters

nuclear factor kappa B subunit 1 ; Homo sapiens







102 Article(s)
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1 31649511 Distinct Signaling Pathways Regulate TREM2 Phagocytic and NFκB Antagonistic Activities. 2019 1
2 30088539 Baicalein alleviates tubular-interstitial nephritis in vivo and in vitro by down-regulating NF-κB and MAPK pathways. 2018 Aug 6 1
3 24742714 Genistein inhibits phorbol ester-induced NF-κB transcriptional activity and COX-2 expression by blocking the phosphorylation of p65/RelA in human mammary epithelial cells. 2014 Oct 1
4 24747121 Sulforaphane inhibits phorbol ester-stimulated IKK-NF-κB signaling and COX-2 expression in human mammary epithelial cells by targeting NF-κB activating kinase and ERK. 2014 Aug 28 2
5 25104352 NF-κB transcriptional activity is modulated by FK506-binding proteins FKBP51 and FKBP52: a role for peptidyl-prolyl isomerase activity. 2014 Sep 19 2
6 21242888 NF-κB/Rel: agonist and antagonist roles in HIV-1 latency. 2011 Jan 1
7 21665893 A protein kinase C/protein kinase D pathway protects LNCaP prostate cancer cells from phorbol ester-induced apoptosis by promoting ERK1/2 and NF-{kappa}B activities. 2011 Aug 1
8 20064506 Nuclear translocation of the 1,25D3-MARRS (membrane associated rapid response to steroids) receptor protein and NFkappaB in differentiating NB4 leukemia cells. 2010 Apr 15 1
9 20504934 Phorbol ester-induced human cytomegalovirus major immediate-early (MIE) enhancer activation through PKC-delta, CREB, and NF-kappaB desilences MIE gene expression in quiescently infected human pluripotent NTera2 cells. 2010 Sep 1
10 20584749 Piceatannol, a catechol-type polyphenol, inhibits phorbol ester-induced NF-{kappa}B activation and cyclooxygenase-2 expression in human breast epithelial cells: cysteine 179 of IKK{beta} as a potential target. 2010 Aug 1
11 20858459 Depletion of the cellular levels of Bag-1 proteins attenuates phorbol ester-induced downregulation of IκBα and nuclear accumulation of NF-κB. 2010 Oct 22 3
12 20155627 Piceatannol inhibits phorbol ester-induced NF-kappa B activation and COX-2 expression in cultured human mammary epithelial cells. 2009 1
13 20168983 Rottlerin inhibits ROS formation and prevents NFkappaB activation in MCF-7 and HT-29 cells. 2009 2
14 17767925 Roles of ERK and p38 mitogen-activated protein kinases in phorbol ester-induced NF-kappaB activation and COX-2 expression in human breast epithelial cells. 2008 Jan 30 1
15 18436431 Phorbol ester-stimulated NF-kappaB-dependent transcription: roles for isoforms of novel protein kinase C. 2008 Jul 1
16 18606397 SH-5, an AKT inhibitor potentiates apoptosis and inhibits invasion through the suppression of anti-apoptotic, proliferative and metastatic gene products regulated by IkappaBalpha kinase activation. 2008 Dec 1 1
17 17479775 Defibrinated bovine plasma inhibits retroviral transcription by blocking p52 activation of the NFkappaB element in the long terminal repeat. 2007 Apr 1
18 17944529 Myricetin down-regulates phorbol ester-induced cyclooxygenase-2 expression in mouse epidermal cells by blocking activation of nuclear factor kappa B. 2007 Nov 14 5
19 16380122 Hirsutenone inhibits phorbol ester-induced upregulation of COX-2 and MMP-9 in cultured human mammary epithelial cells: NF-kappaB as a potential molecular target. 2006 Jan 23 1
20 16551868 A synthetic triterpenoid, CDDO-Me, inhibits IkappaBalpha kinase and enhances apoptosis induced by TNF and chemotherapeutic agents through down-regulation of expression of nuclear factor kappaB-regulated gene products in human leukemic cells. 2006 Mar 15 1
21 16356124 Curcumin inhibits phorbol ester-induced up-regulation of cyclooxygenase-2 and matrix metalloproteinase-9 by blocking ERK1/2 phosphorylation and NF-kappaB transcriptional activity in MCF10A human breast epithelial cells. 2005 Nov-Dec 1
22 14976190 Inhibitors of protein kinase C (PKC) prevent activated transcription: role of events downstream of NF-kappaB DNA binding. 2004 Apr 30 5
23 14981539 Regulation of phorbol ester-mediated TRAF1 induction in human colon cancer cells through a PKC/RAF/ERK/NF-kappaB-dependent pathway. 2004 Mar 11 1
24 15265936 Cyclooxygenase (COX)-2 inhibitor celecoxib abrogates TNF-induced NF-kappa B activation through inhibition of activation of I kappa B alpha kinase and Akt in human non-small cell lung carcinoma: correlation with suppression of COX-2 synthesis. 2004 Aug 1 1
25 12551910 Combined action of ERK and NF kappa B mediates the protective effect of phorbol ester on Fas-induced apoptosis in Jurkat cells. 2003 Mar 28 1
26 12676934 Protein kinase C-associated kinase can activate NFkappaB in both a kinase-dependent and a kinase-independent manner. 2003 Jun 13 1
27 12805425 NF-kappaB is required for apoptosis prevention during herpes simplex virus type 1 infection. 2003 Jul 1
28 12907607 Ursolic acid inhibits nuclear factor-kappaB activation induced by carcinogenic agents through suppression of IkappaBalpha kinase and p65 phosphorylation: correlation with down-regulation of cyclooxygenase 2, matrix metalloproteinase 9, and cyclin D1. 2003 Aug 1 1
29 14555224 Induction of apoptosis by curcumin: mediation by glutathione S-transferase P1-1 inhibition. 2003 Oct 15 1
30 15068390 Monitoring NF-kappa B transactivation potential via real-time PCR quantification of I kappa B-alpha gene expression. 2003 1
31 12091384 Protein kinase C-associated kinase (PKK) mediates Bcl10-independent NF-kappa B activation induced by phorbol ester. 2002 Aug 30 2
32 12214859 Suppression of phorbol ester-induced NF-kappaB activation by capsaicin in cultured human promyelocytic leukemia cells. 2002 Aug 1
33 12297018 Curcumin suppresses activation of NF-kappaB and AP-1 induced by phorbol ester in cultured human promyelocytic leukemia cells. 2002 May 31 1
34 10734024 The luminal short-chain fatty acid butyrate modulates NF-kappaB activity in a human colonic epithelial cell line. 2000 Apr 1
35 10807909 Phorbol esters and cytokines regulate the expression of the NEMO-related protein, a molecule involved in a NF-kappa B-independent pathway. 2000 Jul 28 1
36 11216470 Inhibitory effects of curcumin and capsaicin on phorbol ester-induced activation of eukaryotic transcription factors, NF-kappaB and AP-1. 2000 1
37 9973483 Immunosuppressive leflunomide metabolite (A77 1726) blocks TNF-dependent nuclear factor-kappa B activation and gene expression. 1999 Feb 15 1
38 10206970 4-Hydroxynonenal prevents NF-kappaB activation and tumor necrosis factor expression by inhibiting IkappaB phosphorylation and subsequent proteolysis. 1999 Apr 23 1
39 10439045 Overexpression of gamma-glutamylcysteine synthetase suppresses tumor necrosis factor-induced apoptosis and activation of nuclear transcription factor-kappa B and activator protein-1. 1999 Jul 29 1
40 10454636 Dopamine stimulates expression of the human immunodeficiency virus type 1 via NF-kappaB in cells of the immune system. 1999 Aug 15 1
41 10490923 Polaprezinc down-regulates proinflammatory cytokine-induced nuclear factor-kappaB activiation and interleukin-8 expression in gastric epithelial cells. 1999 Oct 1
42 10496024 [Transcription factor NF-kappa B/RelA are constitutively activated and localized in the cell nuclei of E1A + cHa-Ras transformants]. 1999 1
43 9486988 Sulfasalazine: a potent and specific inhibitor of nuclear factor kappa B. 1998 Mar 1 1
44 9582369 Overexpression of manganese superoxide dismutase suppresses tumor necrosis factor-induced apoptosis and activation of nuclear transcription factor-kappaB and activated protein-1. 1998 May 22 1
45 9593751 Constitutive activation of NF-kappaB causes resistance to apoptosis in human cutaneous T cell lymphoma HuT-78 cells. Autocrine role of tumor necrosis factor and reactive oxygen intermediates. 1998 May 29 1
46 9715269 Activation of NF-kappa B by oncogenic Raf in HEK 293 cells occurs through autocrine recruitment of the stress kinase cascade. 1998 Aug 13 1
47 9195956 Selective involvement of ceramide in cytokine-induced apoptosis. Ceramide inhibits phorbol ester activation of nuclear factor kappaB. 1997 Jun 27 2
48 9218566 Dexamethasone potently enhances phorbol ester-induced IL-1beta gene expression and nuclear factor NF-kappaB activation. 1997 Jul 15 1
49 9374492 Sanguinarine (pseudochelerythrine) is a potent inhibitor of NF-kappaB activation, IkappaBalpha phosphorylation, and degradation. 1997 Nov 28 1
50 9459494 Heavy metal ion induction of adhesion molecules and cytokines in human endothelial cells: the role of NF-kappaB, I kappaB-alpha and AP-1. 1997 1