Fatty Acids, Volatile

free fatty acid receptor 2 ; Homo sapiens







62 Article(s)
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1 34168098 Novel GPR43 Agonists Exert an Anti-Inflammatory Effect in a Colitis Model. 2022 Jan 1 5
2 35203397 Free Fatty Acid Receptors (FFARs) in Adipose: Physiological Role and Therapeutic Outlook. 2022 Feb 21 1
3 33338029 New insights into the links between anti-diabetes drugs and gut microbiota. 2021 Jan 2
4 33769191 Propionate catabolism by CD-associated adherent-invasive E. coli counteracts its anti-inflammatory effect. 2021 Jan-Dec 2
5 33851870 Lung immune tone via gut-lung axis: gut-derived LPS and short-chain fatty acids' immunometabolic regulation of lung IL-1β, FFAR2, and FFAR3 expression. 2021 Jul 1 1
6 33999409 Induction of the apoptosis, degranulation and IL-13 production of human basophils by butyrate and propionate via suppression of histone deacetylation. 2021 Oct 2
7 34112743 The Short-Chain Fatty Acid Receptor GPR43 Modulates YAP/TAZ via RhoA. 2021 Jul 31 2
8 34288488 Structure-Activity Relationship Explorations and Discovery of a Potent Antagonist for the Free Fatty Acid Receptor 2. 2021 Nov 5 2
9 34333988 Essential Hypertension Is Associated With Changes in Gut Microbial Metabolic Pathways: A Multisite Analysis of Ambulatory Blood Pressure. 2021 Sep 2
10 34480991 The role of fatty acids in Crohn's disease pathophysiology - An overview. 2021 Dec 1 1
11 34926327 Short-Chain Fatty Acid and FFAR2 Activation - A New Option for Treating Infections? 2021 1
12 31487233 Free Fatty Acid Receptors in Health and Disease. 2020 Jan 1 2
13 32997697 Acetic acid stimulates G-protein-coupled receptor GPR43 and induces intracellular calcium influx in L6 myotube cells. 2020 2
14 33373277 Physiological concentrations of short-chain fatty acids induce the formation of neutrophil extracellular traps in vitro. 2020 Jan-Dec 1
15 30203438 Short chain fatty acids stimulate insulin secretion and reduce apoptosis in mouse and human islets in vitro: Role of free fatty acid receptor 2. 2019 Feb 1
16 28883043 FFAR2-FFAR3 receptor heteromerization modulates short-chain fatty acid sensing. 2018 Jan 4
17 29431874 Short-chain fatty acids induce tissue plasminogen activator in airway epithelial cells via GPR41&43. 2018 May 3
18 29861709 Expression of GPR43 in Brown Adipogenesis Is Enhanced by Rosiglitazone and Controlled by PPARγ/RXR Heterodimerization. 2018 1
19 30209581 Decreased expression of G-protein-coupled receptors GPR43 and GPR109a in psoriatic skin can be restored by topical application of sodium butyrate. 2018 Nov 1
20 30247908 Discovery of a Potent Thiazolidine Free Fatty Acid Receptor 2 Agonist with Favorable Pharmacokinetic Properties. 2018 Nov 8 1
21 27757764 Application of GPCR Structures for Modelling of Free Fatty Acid Receptors. 2017 1
22 28992793 The Short-Chain Fatty Acid Propionate Inhibits Adipogenic Differentiation of Human Chorion-Derived Mesenchymal Stem Cells Through the Free Fatty Acid Receptor 2. 2017 Dec 1 4
23 26683635 Selective novel inverse agonists for human GPR43 augment GLP-1 secretion. 2016 Jan 15 2
24 26706043 L-rhamnose as a source of colonic propionate inhibits insulin secretion but does not influence measures of appetite or food intake. 2016 Mar 1 1
25 26719580 The Pharmacology and Function of Receptors for Short-Chain Fatty Acids. 2016 Mar 1
26 26739335 G protein-coupled receptors: signalling and regulation by lipid agonists for improved glucose homoeostasis. 2016 Apr 1
27 26852904 Safety, pharmacokinetics and pharmacodynamics of GLPG0974, a potent and selective FFA2 antagonist, in healthy male subjects. 2016 Jul 1
28 27151945 The SCFA butyrate stimulates the epithelial production of retinoic acid via inhibition of epithelial HDAC. 2016 Jun 1 1
29 27348268 An essential role of Ffar2 (Gpr43) in dietary fibre-mediated promotion of healthy composition of gut microbiota and suppression of intestinal carcinogenesis. 2016 Jun 27 2
30 27503855 The Neutrophil Response Induced by an Agonist for Free Fatty Acid Receptor 2 (GPR43) Is Primed by Tumor Necrosis Factor Alpha and by Receptor Uncoupling from the Cytoskeleton but Attenuated by Tissue Recruitment. 2016 Oct 15 1
31 25633224 The short-chain fatty acid receptor GPR43 is transcriptionally regulated by XBP1 in human monocytes. 2015 Jan 30 2
32 25732031 A novel antidiabetic therapy: free fatty acid receptors as potential drug target. 2015 1
33 25828455 Metabolite-sensing receptors GPR43 and GPR109A facilitate dietary fibre-induced gut homeostasis through regulation of the inflammasome. 2015 Apr 1 1
34 25850624 Role of Free Fatty Acid Receptor 2 (FFAR2) in the Regulation of Metabolic Homeostasis. 2015 1
35 25875123 Dietary gut microbial metabolites, short-chain fatty acids, and host metabolic regulation. 2015 Apr 14 2
36 25914362 Editorial: Can GPR43 Sensing of Short-Chain Fatty Acids Unchain Inflammasome-Driven Arthritis? 2015 Jun 1
37 26001654 Intestinal nutrient sensing and blood glucose control. 2015 Jul 1
38 24315753 Identification and characterization of the free fatty acid receptor 2 (FFA2) and a novel functional FFA2-like receptor (FFA2L) for short-chain fatty acids in pigs: evidence for the existence of a duplicated FFA2 gene (FFA2L) in some mammalian species. 2014 Apr 5
39 24926285 The SCFA Receptor GPR43 and Energy Metabolism. 2014 1
40 25227295 Interplay of nutrients and microbial metabolites in intestinal immune homeostasis: distinct and common mechanisms of immune regulation in the small bowel and colon. 2014 1
41 25274213 [Host energy regulation via SCFAs receptors, as dietary nutrition sensors, by gut microbiota]. 2014 2
42 25380412 Discovery and optimization of an azetidine chemical series as a free fatty acid receptor 2 (FFA2) antagonist: from hit to clinic. 2014 Dec 11 1
43 25414667 Free fatty acid receptors as therapeutic targets for the treatment of diabetes. 2014 2
44 23489932 GPR43/FFA2: physiopathological relevance and therapeutic prospects. 2013 Apr 3
45 23852543 The therapeutic potential of GPR43: a novel role in modulating metabolic health. 2013 Dec 1
46 23978504 Transporters and receptors for short-chain fatty acids as the molecular link between colonic bacteria and the host. 2013 Dec 1
47 23985900 β-Arrestin 2 mediates G protein-coupled receptor 43 signals to nuclear factor-κB. 2013 2
48 21825084 Regulation of inflammatory responses by the commensal microbiota. 2012 Jan 1
49 20979106 G-protein-coupled receptor for short-chain fatty acids suppresses colon cancer. 2011 Feb 15 1
50 21113792 Density distribution of free fatty acid receptor 2 (FFA2)-expressing and GLP-1-producing enteroendocrine L cells in human and rat lower intestine, and increased cell numbers after ingestion of fructo-oligosaccharide. 2011 Feb 2