7-hydroxymethotrexate

ATP-binding cassette, sub-family C (CFTR/MRP), member 2 ; Mus musculus







7 Article(s)
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1 29618584 Leflunomide Increases Hepatic Exposure to Methotrexate and Its Metabolite by Differentially Regulating Multidrug Resistance-Associated Protein Mrp2/3/4 Transporters via Peroxisome Proliferator-Activated Receptor α Activation. 2018 Jun 1
2 21566011 Impact of abcc2 [multidrug resistance-associated protein (MRP) 2], abcc3 (MRP3), and abcg2 (breast cancer resistance protein) on the oral pharmacokinetics of methotrexate and its main metabolite 7-hydroxymethotrexate. 2011 Aug 3
3 21841039 Dose-dependent disposition of methotrexate in Abcc2 and Abcc3 gene knockout murine models. 2011 Nov 1
4 19383815 Functionally overlapping roles of Abcg2 (Bcrp1) and Abcc2 (Mrp2) in the elimination of methotrexate and its main toxic metabolite 7-hydroxymethotrexate in vivo. 2009 May 1 4
5 19996279 Abcc2 (Mrp2), Abcc3 (Mrp3), and Abcg2 (Bcrp1) are the main determinants for rapid elimination of methotrexate and its toxic metabolite 7-hydroxymethotrexate in vivo. 2009 Dec 4
6 19088030 Impact of Abcc2 (Mrp2) and Abcc3 (Mrp3) on the in vivo elimination of methotrexate and its main toxic metabolite 7-hydroxymethotrexate. 2008 Dec 15 8
7 15313923 Mechanism of the pharmacokinetic interaction between methotrexate and benzimidazoles: potential role for breast cancer resistance protein in clinical drug-drug interactions. 2004 Aug 15 1