7 Article(s)Download |
PMID | Title | Pub. Year | #Total Relationships |
1 | 29618584 | Leflunomide Increases Hepatic Exposure to Methotrexate and Its Metabolite by Differentially Regulating Multidrug Resistance-Associated Protein Mrp2/3/4 Transporters via Peroxisome Proliferator-Activated Receptor α Activation. | 2018 Jun | 1 |
2 | 21566011 | Impact of abcc2 [multidrug resistance-associated protein (MRP) 2], abcc3 (MRP3), and abcg2 (breast cancer resistance protein) on the oral pharmacokinetics of methotrexate and its main metabolite 7-hydroxymethotrexate. | 2011 Aug | 3 |
3 | 21841039 | Dose-dependent disposition of methotrexate in Abcc2 and Abcc3 gene knockout murine models. | 2011 Nov | 1 |
4 | 19383815 | Functionally overlapping roles of Abcg2 (Bcrp1) and Abcc2 (Mrp2) in the elimination of methotrexate and its main toxic metabolite 7-hydroxymethotrexate in vivo. | 2009 May 1 | 4 |
5 | 19996279 | Abcc2 (Mrp2), Abcc3 (Mrp3), and Abcg2 (Bcrp1) are the main determinants for rapid elimination of methotrexate and its toxic metabolite 7-hydroxymethotrexate in vivo. | 2009 Dec | 4 |
6 | 19088030 | Impact of Abcc2 (Mrp2) and Abcc3 (Mrp3) on the in vivo elimination of methotrexate and its main toxic metabolite 7-hydroxymethotrexate. | 2008 Dec 15 | 8 |
7 | 15313923 | Mechanism of the pharmacokinetic interaction between methotrexate and benzimidazoles: potential role for breast cancer resistance protein in clinical drug-drug interactions. | 2004 Aug 15 | 1 |