Sirolimus

CREB regulated transcription coactivator 1 ; Homo sapiens







33 Article(s)
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#Total Relationships
1 33157024 TORC1 Determines Fab1 Lipid Kinase Function at Signaling Endosomes and Vacuoles. 2021 Jan 25 1
2 33445779 Conserved and Divergent Mechanisms That Control TORC1 in Yeasts and Mammals. 2021 Jan 12 1
3 33740659 Sorting nexin Mdm1/SNX14 regulates nucleolar dynamics at the NVJ after TORC1 inactivation. 2021 May 7 1
4 33744865 Enhancing lifespan of budding yeast by pharmacological lowering of amino acid pools. 2021 Mar 21 1
5 34638732 Relationships between Mitochondrial Function, AMPK, and TORC1 Signaling in Lymphoblasts with Premutation Alleles of the FMR1 Gene. 2021 Sep 27 1
6 34880790 Cellular Bioenergetics and AMPK and TORC1 Signalling in Blood Lymphoblasts Are Biomarkers of Clinical Status in FMR1 Premutation Carriers. 2021 1
7 31546204 The regulation of rapamycin in planarian Dugesia japonica Ichikawa & Kawakatsu, 1964 regeneration according to TOR signaling pathway. 2019 Dec 15 2
8 28648781 PP2A Controls Genome Integrity by Integrating Nutrient-Sensing and Metabolic Pathways with the DNA Damage Response. 2017 Jul 20 1
9 29062000 FTY720-induced endocytosis of yeast and human amino acid transporters is preceded by reduction of their inherent activity and TORC1 inhibition. 2017 Oct 23 1
10 27065332 Phosphatidylinositol-3 kinase-dependent translational regulation of Id1 involves the PPM1G phosphatase. 2016 Nov 3 1
11 27153139 Critical role of lysosomes in the dysfunction of human Cardiac Stem Cells obtained from failing hearts. 2016 Aug 1 1
12 27161823 TORC2 Structure and Function. 2016 Jun 1
13 26024867 GATA Factor Regulation in Excess Nitrogen Occurs Independently of Gtr-Ego Complex-Dependent TorC1 Activation. 2015 May 29 1
14 26147250 MTOR regulates the pro-tumorigenic senescence-associated secretory phenotype by promoting IL1A translation. 2015 Aug 1
15 26452980 Co-administration of the mTORC1/TORC2 inhibitor INK128 and the Bcl-2/Bcl-xL antagonist ABT-737 kills human myeloid leukemia cells through Mcl-1 down-regulation and AKT inactivation. 2015 Dec 1
16 24344203 Isp7 is a novel regulator of amino acid uptake in the TOR signaling pathway. 2014 Mar 1
17 24718867 Sustained inhibition of receptor tyrosine kinases and macrophage depletion by PLX3397 and rapamycin as a potential new approach for the treatment of MPNSTs. 2014 Jun 15 1
18 24970820 Insights from yeast into whether the inhibition of heat shock transcription factor (Hsf1) by rapamycin can prevent the Hsf1 activation that results from treatment with an Hsp90 inhibitor. 2014 Jul 15 1
19 25073740 Molecular architecture and function of the SEA complex, a modulator of the TORC1 pathway. 2014 Nov 1
20 23117620 Ferulic acid induces mammalian target of rapamycin inactivation in cultured mammalian cells. 2013 1
21 23184930 Alterations in the Ure2 αCap domain elicit different GATA factor responses to rapamycin treatment and nitrogen limitation. 2013 Jan 18 1
22 23601176 Reducing signs of aging and increasing lifespan by drug synergy. 2013 Aug 2
23 23689994 Subconjunctival Palomid 529 in the treatment of neovascular age-related macular degeneration. 2013 Dec 1
24 23826334 Deletion of the fission yeast homologue of human insulinase reveals a TORC1-dependent pathway mediating resistance to proteotoxic stress. 2013 1
25 23935103 Five conditions commonly used to down-regulate tor complex 1 generate different physiological situations exhibiting distinct requirements and outcomes. 2013 Sep 20 1
26 21317285 WIPI1 coordinates melanogenic gene transcription and melanosome formation via TORC1 inhibition. 2011 Apr 8 1
27 20072130 Effective and selective targeting of leukemia cells using a TORC1/2 kinase inhibitor. 2010 Feb 1
28 20404504 A functional link between polo-like kinase 1 and the mammalian target-of-rapamycin pathway? 2010 May 1
29 20549474 New inhibitors of the PI3K-Akt-mTOR pathway: insights into mTOR signaling from a new generation of Tor Kinase Domain Inhibitors (TORKinibs). 2010 1
30 19374918 Therapeutic role of sirolimus in non-transplant kidney disease. 2009 Aug 3
31 19586661 Enhanced interaction between Hsp90 and raptor regulates mTOR signaling upon T cell activation. 2009 Aug 1
32 19100909 mTOR-what does it do? 2008 Dec 1
33 16627617 TSC1/TSC2 and Rheb have different effects on TORC1 and TORC2 activity. 2006 May 2 1