2-aminopyrimidine

ABL proto-oncogene 1, non-receptor tyrosine kinase ; Homo sapiens







7 Article(s)
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1 21861543 Nilotinib: in the first-line treatment of newly diagnosed Philadelphia chromosome-positive chronic myeloid leukaemia in chronic phase. 2011 Aug 20 1
2 19920925 Nilotinib: optimal therapy for patients with chronic myeloid leukemia and resistance or intolerance to imatinib. 2009 Sep 21 1
3 18956997 Nilotinib: a new tyrosine kinase inhibitor for the treatment of chronic myelogenous leukemia. 2008 Nov 1
4 17613767 The tyrosine kinase inhibitor AMN107 (Nilotinib) exhibits off-target effects in lymphoblastic cell lines. 2007 Jul 1
5 16000593 AMN107, a novel aminopyrimidine inhibitor of Bcr-Abl, has in vitro activity against imatinib-resistant chronic myeloid leukemia. 2005 Jul 1 1
6 16078266 AMN107, a novel aminopyrimidine inhibitor of p190 Bcr-Abl activation and of in vitro proliferation of Philadelphia-positive acute lymphoblastic leukemia cells. 2005 Sep 15 1
7 11512149 Mechanisms of resistance imatinib (STI571) in preclinical models and in leukemia patients. 2001 Feb 1