Phenobarbital

cytochrome P450, family 3, subfamily a, polypeptide 11 ; Mus musculus







19 Article(s)
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Pub. Year
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1 30503582 Strain differences between CD-1 and C57BL/6 mice in expression of metabolic enzymes and DNA methylation modifications of the primary hepatocytes. 2019 Jan 15 1
2 28218408 Toxaphene-induced mouse liver tumorigenesis is mediated by the constitutive androstane receptor. 2017 Aug 2
3 26400395 Dose of Phenobarbital and Age of Treatment at Early Life are Two Key Factors for the Persistent Induction of Cytochrome P450 Enzymes in Adult Mouse Liver. 2015 Dec 2
4 20403969 Human constitutive androstane receptor (CAR) and pregnane X receptor (PXR) support the hypertrophic but not the hyperplastic response to the murine nongenotoxic hepatocarcinogens phenobarbital and chlordane in vivo. 2010 Aug 1
5 19666990 Inoculation of human tumor cells alters the basal expression but not the inducibility of cytochrome P450 enzymes in tumor-bearing mouse liver. 2009 Nov 1
6 18677425 A novel panel of mouse models to evaluate the role of human pregnane X receptor and constitutive androstane receptor in drug response. 2008 Sep 1
7 15936348 Dimemorfan N-demethylation by mouse liver microsomal cytochrome P450 enzymes. 2005 Jul 1 2
8 16109766 Transcription coactivator peroxisome proliferator-activated receptor-binding protein/mediator 1 deficiency abrogates acetaminophen hepatotoxicity. 2005 Aug 30 1
9 14770174 CAR/PXR provide directives for Cyp3a41 gene regulation differently from Cyp3a11. 2004 1
10 15183191 Kupffer cells and reactive oxygen species partially mediate lipopolysaccharide-induced downregulation of nuclear receptor pregnane x receptor and its target gene CYP3a in mouse liver. 2004 Jul 1 2
11 15272053 Meclizine is an agonist ligand for mouse constitutive androstane receptor (CAR) and an inverse agonist for human CAR. 2004 Oct 1
12 14569871 [Activity and induction of CYP2B, CYP2C, and CYP3A in tissues of cyclophosphane-sensitive and resistant neoplasms and the liver of neoplasm-carrying mice]. 2003 Jan-Feb 2
13 11752199 Diverse roles of the nuclear orphan receptor CAR in regulating hepatic genes in response to phenobarbital. 2002 Jan 1
14 11861787 Enhanced induction of cytochrome P450 enzymes and CAR binding in TNF (p55(-/-)/p75(-/-)) double receptor knockout mice following phenobarbital treatment. 2002 Mar 1
15 12051692 Paraquat detoxicative system in the mouse liver postmitochondrial fraction. 2002 Jun 1 1
16 11589781 Gene induction by Phenobarbital: an update on an old question that receives key novel answers. 2001 Sep 1
17 10681370 The glucocorticoid receptor is essential for induction of cytochrome P-4502B by steroids but not for drug or steroid induction of CYP3A or P-450 reductase in mouse liver. 2000 Mar 1
18 10820145 Use of a novel real-time quantitative reverse transcription-polymerase chain reaction method to study the effects of cytokines on cytochrome P450 mRNA expression in mouse liver. 2000 Jun 1
19 10454503 Involvement of cyclic nucleotide- and calcium-regulated pathways in phenobarbital-induced cytochrome P-450 3A expression in mouse primary hepatocytes. 1999 Sep 9