Lovastatin

cyclin dependent kinase inhibitor 1A ; Homo sapiens







11 Article(s)
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1 31821701 Lovastatin-mediated MCF-7 cancer cell death involves LKB1-AMPK-p38MAPK-p53-survivin signalling cascade. 2020 Jan 2
2 27122225 Lovastatin causes FaDu hypopharyngeal carcinoma cell death via AMPK-p63-survivin signaling cascade. 2016 Apr 28 4
3 25605247 Statin-induced depletion of geranylgeranyl pyrophosphate inhibits cell proliferation by a novel pathway of Skp2 degradation. 2015 Feb 20 1
4 18188523 Effects of lovastatin alone or combined with irradiation on tumor cells in vitro and in vivo. 2008 Jan 1
5 18695886 BRCA1 overexpression sensitizes cancer cells to lovastatin via regulation of cyclin D1-CDK4-p21WAF1/CIP1 pathway: analyses using a breast cancer cell line and tumoral xenograft model. 2008 Sep 3
6 17158337 Critical role for FoxO3a-dependent regulation of p21CIP1/WAF1 in response to statin signaling in cardiac myocytes. 2007 Jan 5 4
7 16424040 Farnesyl and geranylgeranyl transferase inhibitors induce G1 arrest by targeting the proteasome. 2006 Jan 15 1
8 9864387 Lovastatin induces p21WAF1/Cip1 in human vascular smooth muscle cells: influence on protein phosphorylation, cell cycle, induction of apoptosis, and growth inhibition. 1999 Jan 1
9 10393901 Lovastatin-mediated G1 arrest is through inhibition of the proteasome, independent of hydroxymethyl glutaryl-CoA reductase. 1999 Jul 6 3
10 9553123 Inhibition of the 3-hydroxy-3-methylglutaryl-coenzyme A reductase pathway induces p53-independent transcriptional regulation of p21(WAF1/CIP1) in human prostate carcinoma cells. 1998 Apr 24 5
11 9044834 Lovastatin induction of cyclin-dependent kinase inhibitors in human breast cells occurs in a cell cycle-independent fashion. 1997 Feb 15 1