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33576217 | Effect of Valproic Acid on the Class I Histone Deacetylase 1, 2 and 3, Tumor Suppressor Genes p21WAF1/CIP1 and p53, and Intrinsic Mitochondrial Apoptotic Pathway, Pro- (Bax, Bak, and Bim) and anti- (Bcl-2, Bcl-xL, and Mcl-1) Apoptotic Genes Expression, Cell Viability, and Apoptosis Induction in Hepatocellular Carcinoma HepG2 Cell Line. | 2021 Feb 1 |
7 |
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31516890 | Effect of 5-Aza-2'-Deoxycytidine in Comparison to Valproic Acid and Trichostatin A on Histone Deacetylase 1, DNA Methyltransferase 1, and CIP/KIP Family (p21, p27, and p57) Genes Expression, Cell Growth Inhibition, and Apoptosis Induction in Colon Cancer SW480 Cell Line. | 2019 |
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22968660 | Notch1 signaling is irresponsible to the anti-leukemic effect of HDACis in B-ALL Nalm-6 cells. | 2013 Jan |
1 |
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22303878 | Hyper-activation of WNT/β-catenin signaling pathway mediates anti-tumor effects of histone deacetylase inhibitors in acute T lymphoblastic leukemia. | 2012 Sep |
2 |
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23093837 | Mechanism of growth inhibition of prostate cancer xenografts by valproic acid. | 2012 |
1 |
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21519790 | Histone deacetylase inhibitors, valproic acid and trichostatin-A induce apoptosis and affect acetylation status of p53 in ERG-positive prostate cancer cells. | 2011 Jul |
3 |
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19176032 | [Inhibitory effect of valproic acid on cell cycle of Kasumi-1 cell line and its mechanism]. | 2008 Dec |
2 |
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17218782 | Valproic acid induces apoptosis, p16INK4A upregulation and sensitization to chemotherapy in human melanoma cells. | 2007 Feb |
1 |
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17534580 | Valproic acid induces p21 and topoisomerase-II (alpha/beta) expression and synergistically enhances etoposide cytotoxicity in human glioblastoma cell lines. | 2007 Nov |
3 |
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16990052 | Valproic acid, a histone deacetylase inhibitor, is an antagonist for oncolytic adenoviral gene therapy. | 2006 Dec |
3 |
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15870934 | p21Waf1/Cip1 is a common target induced by short-chain fatty acid HDAC inhibitors (valproic acid, tributyrin and sodium butyrate) in neuroblastoma cells. | 2005 Jun |
4 |
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15927669 | Antileukemia activity of the combination of 5-aza-2'-deoxycytidine with valproic acid. | 2005 Jul |
1 |
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16373706 | Valproic acid induces growth arrest, apoptosis, and senescence in medulloblastomas by increasing histone hyperacetylation and regulating expression of p21Cip1, CDK4, and CMYC. | 2005 Dec |
2 |