Inositol

endoplasmic reticulum (ER) to nucleus signalling 1 ; Mus musculus







53 Article(s)
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1 34808241 The Endoplasmic Reticulum Stress Sensor IRE1α Regulates the UV DNA Repair Response through the Control of Intracellular Calcium Homeostasis. 2022 Jun 1
2 35304860 The unfolded protein response transducer IRE1α promotes reticulophagy in podocytes. 2022 Jun 1 1
3 35379745 Prostaglandin E2-Induced AKT Activation Regulates the Life Span of Short-Lived Plasma Cells by Attenuating IRE1α Hyperactivation. 2022 Apr 15 1
4 32915195 Targeting of BCR-ABL1 and IRE1α induces synthetic lethality in Philadelphia-positive acute lymphoblastic leukemia. 2021 Feb 25 1
5 33879967 Targeted deletion of Atg5 in intestinal epithelial cells promotes dextran sodium sulfate-induced colitis. 2021 Mar 2
6 34027646 Diet-induced differential effects on plasma lipids secretion by the inositol-requiring transmembrane kinase/endoribonuclease 1α. 2021 Apr 30 1
7 34375928 Imeglimin prevents heart failure with preserved ejection fraction by recovering the impaired unfolded protein response in mice subjected to cardiometabolic stress. 2021 Oct 1 1
8 34407601 Therapeutic targeting of endoplasmic reticulum stress in acute graft-versus-host disease. 2021 Aug 19 1
9 34502057 Cereulide Exposure Caused Cytopathogenic Damages of Liver and Kidney in Mice. 2021 Aug 24 1
10 34675883 Pharmacological Inhibition of Inositol-Requiring Enzyme 1α RNase Activity Protects Pancreatic Beta Cell and Improves Diabetic Condition in Insulin Mutation-Induced Diabetes. 2021 1
11 31827236 SPHK1 deficiency protects mice from acetaminophen-induced ER stress and mitochondrial permeability transition. 2020 Jun 1
12 31846435 Selenoprotein S regulates adipogenesis through IRE1α-XBP1 pathway. 2020 Mar 1
13 32520957 IRE1α regulates macrophage polarization, PD-L1 expression, and tumor survival. 2020 Jun 1
14 33298866 Role of IRE1α in podocyte proteostasis and mitochondrial health. 2020 Nov 19 1
15 30630412 Treatment of established TH2 cells with 4μ8c, an inhibitor of IRE1α, blocks IL-5 but not IL-4 secretion. 2019 Jan 10 1
16 30943188 A vascular smooth muscle cell X-box binding protein 1 and transglutaminase 2 regulatory circuit limits neointimal hyperplasia. 2019 1
17 31081266 Human placenta-derived mesenchymal stem cells inhibit apoptosis of granulosa cells induced by IRE1α pathway in autoimmune POF mice. 2019 Aug 1
18 31123148 Coupling of COPII vesicle trafficking to nutrient availability by the IRE1α-XBP1s axis. 2019 Jun 11 1
19 31163320 Exosomes from Microglia Attenuate Photoreceptor Injury and Neovascularization in an Animal Model of Retinopathy of Prematurity. 2019 Jun 7 1
20 31578081 Anti-Inflammatory Effects of HDL (High-Density Lipoprotein) in Macrophages Predominate Over Proinflammatory Effects in Atherosclerotic Plaques. 2019 Dec 1
21 31921161 Molecular Insight Into the IRE1α-Mediated Type I Interferon Response Induced by Proteasome Impairment in Myeloid Cells of the Brain. 2019 1
22 29377207 Farnesoid X receptor signaling activates the hepatic X-box binding protein 1 pathway in vitro and in mice. 2018 Jul 1
23 29457838 Bax inhibitor-1 protects from nonalcoholic steatohepatitis by limiting inositol-requiring enzyme 1 alpha signaling in mice. 2018 Aug 1
24 29504610 PI3Kδ contributes to ER stress-associated asthma through ER-redox disturbances: the involvement of the RIDD-RIG-I-NF-κB axis. 2018 Feb 16 2
25 29506314 Dual role for inositol-requiring enzyme 1α in promoting the development of hepatocellular carcinoma during diet-induced obesity in mice. 2018 Aug 1
26 29673059 The TLR4-IRE1α pathway activation contributes to palmitate-elicited lipotoxicity in hepatocytes. 2018 Jul 1
27 29732320 Activation of Host IRE1α-Dependent Signaling Axis Contributes the Intracellular Parasitism of Brucella melitensis. 2018 1
28 29764990 IRE1α prevents hepatic steatosis by processing and promoting the degradation of select microRNAs. 2018 May 15 1
29 30135303 Localized hypoxia links ER stress to lung fibrosis through induction of C/EBP homologous protein. 2018 Aug 23 1
30 30146262 Selenoprotein S protects against adipocyte death through mediation of the IRE1α-sXBP1 pathway. 2018 Sep 18 1
31 30319453 Incorporation of the Endoplasmic Reticulum Stress-Induced Spliced Form of XBP1 mRNA in the Exosomes. 2018 1
32 30538632 Inositol-Requiring Enzyme 1 Alpha Endoribonuclease Specific Inhibitor STF-083010 Alleviates Carbon Tetrachloride Induced Liver Injury and Liver Fibrosis in Mice. 2018 1
33 30559399 Stabilization of cytokine mRNAs in iNKT cells requires the serine-threonine kinase IRE1alpha. 2018 Dec 17 2
34 28039331 Hepatic deletion of X-box binding protein 1 impairs bile acid metabolism in mice. 2017 Mar 1
35 28098884 Renin-angiotensin system activation accelerates atherosclerosis in experimental renal failure by promoting endoplasmic reticulum stress-related inflammation. 2017 Mar 1
36 28346409 The metabolic ER stress sensor IRE1α suppresses alternative activation of macrophages and impairs energy expenditure in obesity. 2017 May 1
37 28428258 Deletion of inositol-requiring enzyme-1α in podocytes disrupts glomerular capillary integrity and autophagy. 2017 Jun 15 1
38 29098149 Regulation of IRE1α by the small molecule inhibitor 4μ8c in hepatoma cells. 2017 Apr 1
39 27186946 Ginkgolide K protects the heart against endoplasmic reticulum stress injury by activating the inositol-requiring enzyme 1α/X box-binding protein-1 pathway. 2016 Aug 1
40 27558934 Knockout of inositol-requiring enzyme 1α in pro-opiomelanocortin neurons decreases fat mass via increasing energy expenditure. 2016 Aug 1
41 25457211 Role for the endoplasmic reticulum stress sensor IRE1α in liver regenerative responses. 2015 Mar 1
42 26469762 The IRE1α/XBP1s Pathway Is Essential for the Glucose Response and Protection of β Cells. 2015 Oct 1
43 26484121 Genome-wide analysis of thapsigargin-induced microRNAs and their targets in NIH3T3 cells. 2014 Dec 1
44 23184933 XBP1 mRNA splicing triggers an autophagic response in endothelial cells through BECLIN-1 transcriptional activation. 2013 Jan 11 1
45 23711292 Inhibition of x-box binding protein 1 reduces tunicamycin-induced apoptosis in aged murine macrophages. 2013 Oct 1
46 24089213 Paneth cells as a site of origin for intestinal inflammation. 2013 Nov 14 1
47 21703174 Cdc42 and Rac1 are major contributors to the saturated fatty acid-stimulated JNK pathway in hepatocytes. 2012 Jan 1
48 22128176 Dissociation of inositol-requiring enzyme (IRE1α)-mediated c-Jun N-terminal kinase activation from hepatic insulin resistance in conditional X-box-binding protein-1 (XBP1) knock-out mice. 2012 Jan 20 1
49 20587749 Deletion of Nck1 attenuates hepatic ER stress signaling and improves glucose tolerance and insulin signaling in liver of obese mice. 2011 Mar 1
50 21407177 The unfolded protein response transducer IRE1α prevents ER stress-induced hepatic steatosis. 2011 Apr 6 1