| 1 |
31908154 | Tacrolimus-induced hypomagnesemia and hypercalciuria requires FKBP12 suggesting a role for calcineurin. | 2020 Jan |
3 |
| 2 |
30294901 | Rapamycin and FK506 derivative TH2849 could ameliorate neurodegenerative diseases through autophagy with low immunosuppressive effect. | 2019 Apr |
2 |
| 3 |
26432904 | Renal Deletion of 12 kDa FK506-Binding Protein Attenuates Tacrolimus-Induced Hypertension. | 2016 May |
3 |
| 4 |
27190501 | Timcodar (VX-853) Is a Non-FKBP12 Binding Macrolide Derivative That Inhibits PPARγ and Suppresses Adipogenesis. | 2016 |
1 |
| 5 |
22495293 | Endothelial cell transforming growth factor-β receptor activation causes tacrolimus-induced renal arteriolar hyalinosis. | 2012 Oct |
3 |
| 6 |
21163525 | Immunophilin deficiency augments Ca2+-dependent glutamate release from mouse cortical astrocytes. | 2011 Jan |
1 |
| 7 |
21288594 | Transduced PEP-1-FK506BP inhibits the inflammatory response in the Raw 264.7 cell and mouse models. | 2011 Jul |
1 |
| 8 |
21430698 | Transduced PEP-1-FK506BP ameliorates atopic dermatitis in NC/Nga mice. | 2011 Jul |
4 |
| 9 |
21518963 | FK506 binding protein 12 deficiency in endothelial and hematopoietic cells decreases regulatory T cells and causes hypertension. | 2011 Jun |
4 |
| 10 |
20164329 | Inhibition of FK506 binding proteins reduces alpha-synuclein aggregation and Parkinson's disease-like pathology. | 2010 Feb 17 |
1 |
| 11 |
20674565 | Comparison of the efficacy of tacrolimus and cyclosporine A in a murine model of dinitrofluorobenzene-induced atopic dermatitis. | 2010 Oct 25 |
2 |
| 12 |
19177155 | Tacrolimus reduces nitric oxide synthase function by binding to FKBP rather than by its calcineurin effect. | 2009 Apr |
2 |
| 13 |
17478757 | Removal of FKBP12/12.6 from endothelial ryanodine receptors leads to an intracellular calcium leak and endothelial dysfunction. | 2007 Jul |
4 |
| 14 |
11890899 | FK506 induces chondrogenic differentiation of clonal mouse embryonic carcinoma cells, ATDC5. | 2002 Feb 22 |
6 |
| 15 |
11907581 | Oestrogen protects FKBP12.6 null mice from cardiac hypertrophy. | 2002 Mar 21 |
2 |
| 16 |
12085010 | FKBP12 is the only FK506 binding protein mediating T-cell inhibition by the immunosuppressant FK506. | 2002 Jun 15 |
3 |
| 17 |
12414688 | Ca(2+)-dependent interaction between FKBP12 and calcineurin regulates activity of the Ca(2+) release channel in skeletal muscle. | 2002 Nov |
1 |
| 18 |
11171588 | Muscarinic stimulation increases basal Ca(2+) and inhibits spontaneous Ca(2+) transients in murine colonic myocytes. | 2001 Mar |
1 |
| 19 |
11226255 | FKBP12, the 12-kDa FK506-binding protein, is a physiologic regulator of the cell cycle. | 2001 Feb 27 |
1 |
| 20 |
10710358 | K(+) currents responsible for repolarization in mouse ventricle and their modulation by FK-506 and rapamycin. | 2000 Mar |
1 |
| 21 |
10336507 | Immunophilin FK506-binding protein 52 (not FK506-binding protein 12) mediates the neurotrophic action of FK506. | 1999 Jun |
1 |
| 22 |
10531391 | Calcineurin enhances acetylcholinesterase mRNA stability during C2-C12 muscle cell differentiation. | 1999 Nov |
1 |
| 23 |
9446649 | Stimulating cell proliferation through the pharmacologic activation of c-kit. | 1998 Feb 1 |
2 |
| 24 |
9448138 | A tacrolimus-related immunosuppressant with reduced toxicity. | 1998 Jan 15 |
2 |
| 25 |
9461216 | Cardiac defects and altered ryanodine receptor function in mice lacking FKBP12. | 1998 Jan 29 |
1 |
| 26 |
9016789 | Rapamycin potentiates dexamethasone-induced apoptosis and inhibits JNK activity in lymphoblastoid cells. | 1997 Jan 13 |
1 |
| 27 |
7530743 | The complex of FK506-binding protein 12 and FK506 inhibits calcineurin phosphatase activity and IgE activation-induced cytokine transcripts, but not exocytosis, in mouse mast cells. | 1995 Feb 15 |
8 |
| 28 |
7545671 | Rapamycin, wortmannin, and the methylxanthine SQ20006 inactivate p70s6k by inducing dephosphorylation of the same subset of sites. | 1995 Sep 8 |
1 |
| 29 |
7681074 | A role for calcineurin in degranulation of murine cytotoxic T lymphocytes. | 1993 Apr 1 |
1 |
| 30 |
1377606 | Rapamycin-FKBP specifically blocks growth-dependent activation of and signaling by the 70 kd S6 protein kinases. | 1992 Jun 26 |
1 |
| 31 |
1382293 | Effects of cyclosporin A and FK506 on Fc epsilon receptor type I-initiated increases in cytokine mRNA in mouse bone marrow-derived progenitor mast cells: resistance to FK506 is associated with a deficiency in FK506-binding protein FKBP12. | 1992 Sep 15 |
1 |