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34978024 | Electrophysiological Studies Support Utility of Positive Modulators of SK Channels for the Treatment of Spinocerebellar Ataxia Type 2. | 2022 Jan 3 |
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33577922 | Atxn2-CAG100-KnockIn mouse spinal cord shows progressive TDP43 pathology associated with cholesterol biosynthesis suppression. | 2021 May |
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32307524 | ALS-associated genes in SCA2 mouse spinal cord transcriptomes. | 2020 Jun 27 |
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32932600 | Mouse Ataxin-2 Expansion Downregulates CamKII and Other Calcium Signaling Factors, Impairing Granule-Purkinje Neuron Synaptic Strength. | 2020 Sep 12 |
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31766565 | In Human and Mouse Spino-Cerebellar Tissue, Ataxin-2 Expansion Affects Ceramide-Sphingomyelin Metabolism. | 2019 Nov 21 |
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30194296 | Staufen1 links RNA stress granules and autophagy in a model of neurodegeneration. | 2018 Sep 7 |
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| 7 |
26868665 | Atxn2 Knockout and CAG42-Knock-in Cerebellum Shows Similarly Dysregulated Expression in Calcium Homeostasis Pathway. | 2017 Feb |
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28405022 | Therapeutic reduction of ataxin-2 extends lifespan and reduces pathology in TDP-43 mice. | 2017 Apr 20 |
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| 9 |
28525545 | Gene co-expression network analysis for identifying modules and functionally enriched pathways in SCA2. | 2017 Aug 15 |
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25721894 | Genetic ablation of ataxin-2 increases several global translation factors in their transcript abundance but decreases translation rate. | 2015 Jul |
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25790475 | Both ubiquitin ligases FBXW8 and PARK2 are sequestrated into insolubility by ATXN2 PolyQ expansions, but only FBXW8 expression is dysregulated. | 2015 |
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25902068 | Ataxin-2 regulates RGS8 translation in a new BAC-SCA2 transgenic mouse model. | 2015 Apr |
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| 13 |
23087021 | Changes in Purkinje cell firing and gene expression precede behavioral pathology in a mouse model of SCA2. | 2013 Jan 15 |
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22914732 | ETS1 regulates the expression of ATXN2. | 2012 Dec 1 |
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| 15 |
22973002 | Chronic suppression of inositol 1,4,5-triphosphate receptor-mediated calcium signaling in cerebellar purkinje cells alleviates pathological phenotype in spinocerebellar ataxia 2 mice. | 2012 Sep 12 |
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| 16 |
23102227 | Selective positive modulator of calcium-activated potassium channels exerts beneficial effects in a mouse model of spinocerebellar ataxia type 2. | 2012 Oct 26 |
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| 17 |
21824437 | Mesenchymal stem cell transplantation ameliorates motor function deterioration of spinocerebellar ataxia by rescuing cerebellar Purkinje cells. | 2011 Aug 8 |
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| 18 |
19625506 | Deranged calcium signaling and neurodegeneration in spinocerebellar ataxia type 2. | 2009 Jul 22 |
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| 19 |
18250099 | Insulin receptor and lipid metabolism pathology in ataxin-2 knock-out mice. | 2008 May 15 |
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| 20 |
18602463 | Ataxin-2 associates with the endocytosis complex and affects EGF receptor trafficking. | 2008 Oct |
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| 21 |
17949716 | Ataxin-2 mediated cell death is dependent on domains downstream of the polyQ repeat. | 2007 Dec |
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| 22 |
9020849 | Instability of highly expanded CAG repeats in mice transgenic for the Huntington's disease mutation. | 1997 Feb |
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