| 1 |
34350994 | The RNA-binding protein and stress granule component ATAXIN-2 is expressed in mouse and human tissues associated with glaucoma pathogenesis. | 2022 Feb |
2 |
| 2 |
35511239 | Parallel Appearance of Polyglutamine and Transactivation-Responsive DNA-Binding Protein 43 and Their Complementary Subcellular Localization in Brains of Patients With Spinocerebellar Ataxia Type 2. | 2022 Jun 20 |
5 |
| 3 |
35521889 | ATXN2 intermediate expansions in amyotrophic lateral sclerosis. | 2022 May 6 |
5 |
| 4 |
34390268 | RNA Toxicity and Perturbation of rRNA Processing in Spinocerebellar Ataxia Type 2. | 2021 Nov |
2 |
| 5 |
34565721 | Effect of CAG repeats on the age at onset of patients with spinocerebellar ataxia type 2 in China. | 2021 Aug 28 |
1 |
| 6 |
34845184 | Autophagy in Spinocerebellar ataxia type 2, a dysregulated pathway, and a target for therapy. | 2021 Nov 29 |
2 |
| 7 |
32581673 | The Mechanisms of Nuclear Proteotoxicity in Polyglutamine Spinocerebellar Ataxias. | 2020 |
1 |
| 8 |
32581696 | Gene Deregulation and Underlying Mechanisms in Spinocerebellar Ataxias With Polyglutamine Expansion. | 2020 |
1 |
| 9 |
32962458 | Polyglutamine spinocerebellar ataxias: emerging therapeutic targets. | 2020 Nov |
2 |
| 10 |
30707359 | EvoPPI 1.0: a Web Platform for Within- and Between-Species Multiple Interactome Comparisons and Application to Nine PolyQ Proteins Determining Neurodegenerative Diseases. | 2019 Mar |
2 |
| 11 |
30718627 | Modeling spinocerebellar ataxias 2 and 3 with iPSCs reveals a role for glutamate in disease pathology. | 2019 Feb 4 |
1 |
| 12 |
31435879 | Molecular Mechanisms and Therapeutics for Spinocerebellar Ataxia Type 2. | 2019 Oct |
3 |
| 13 |
33324888 | New alternative splicing variants of the ATXN2 transcript. | 2019 |
1 |
| 14 |
29080331 | OPTN p.Met468Arg and ATXN2 intermediate length polyQ extension in families with C9orf72 mediated amyotrophic lateral sclerosis and frontotemporal dementia. | 2018 Jan |
2 |
| 15 |
29427103 | Spinocerebellar Ataxia Type 2. | 2018 |
4 |
| 16 |
29653012 | [Advance in research on spinocerebellar ataxia 2]. | 2018 Apr 10 |
1 |
| 17 |
29869836 | Ataxin-2: A versatile posttranscriptional regulator and its implication in neural function. | 2018 Nov |
1 |
| 18 |
30194296 | Staufen1 links RNA stress granules and autophagy in a model of neurodegeneration. | 2018 Sep 7 |
3 |
| 19 |
30417124 | Conserved Pbp1/Ataxin-2 regulates retrotransposon activity and connects polyglutamine expansion-driven protein aggregation to lifespan-controlling rDNA repeats. | 2018 |
1 |
| 20 |
30473770 | Recent advances in understanding dominant spinocerebellar ataxias from clinical and genetic points of view. | 2018 |
2 |
| 21 |
26861241 | Effects of the enlargement of polyglutamine segments on the structure and folding of ataxin-2 and ataxin-3 proteins. | 2017 Feb |
2 |
| 22 |
27494456 | C9ORF72 is a GDP/GTP exchange factor for Rab8 and Rab39 and regulates autophagy. | 2017 Jul 3 |
2 |
| 23 |
28527524 | C9orf72 hexanucleotide repeat expansions and Ataxin 2 intermediate length repeat expansions in Indian patients with amyotrophic lateral sclerosis. | 2017 Aug |
1 |
| 24 |
26510381 | Fragment based G-QSAR and molecular dynamics based mechanistic simulations into hydroxamic-based HDAC inhibitors against spinocerebellar ataxia. | 2016 Oct |
3 |
| 25 |
26733254 | ATNX2 is not a regulatory gene in Italian amyotrophic lateral sclerosis patients with C9ORF72 GGGGCC expansion. | 2016 Mar |
1 |
| 26 |
27103069 | Loss of C9ORF72 impairs autophagy and synergizes with polyQ Ataxin-2 to induce motor neuron dysfunction and cell death. | 2016 Jun 15 |
2 |
| 27 |
27531668 | ATXN2-AS, a gene antisense to ATXN2, is associated with spinocerebellar ataxia type 2 and amyotrophic lateral sclerosis. | 2016 Oct |
4 |
| 28 |
27597528 | Search for SCA2 blood RNA biomarkers highlights Ataxin-2 as strong modifier of the mitochondrial factor PINK1 levels. | 2016 Dec |
4 |
| 29 |
25457026 | Intermediate-length polyglutamine in ATXN2 is a possible risk factor among Eastern Chinese patients with amyotrophic lateral sclerosis. | 2015 Mar |
4 |
| 30 |
25527265 | ATXN2 polyQ intermediate repeats are a modifier of ALS survival. | 2015 Jan 20 |
3 |
| 31 |
26086378 | Repeat Associated Non-AUG Translation (RAN Translation) Dependent on Sequence Downstream of the ATXN2 CAG Repeat. | 2015 |
1 |
| 32 |
26208502 | ATXN2 is a modifier of phenotype in ALS patients of Sardinian ancestry. | 2015 Oct |
2 |
| 33 |
23889603 | TDP-43 pathology in polyglutamine diseases: with reference to amyotrphic lateral sclerosis. | 2014 Feb |
1 |
| 34 |
24269018 | Evaluating noncoding nucleotide repeat expansions in amyotrophic lateral sclerosis. | 2014 Apr |
1 |
| 35 |
24534762 | Evaluation of polyglutamine repeats in autosomal dominant Parkinson's disease. | 2014 Jul |
2 |
| 36 |
24718895 | FTLD-ALS of TDP-43 type and SCA2 in a family with a full ataxin-2 polyglutamine expansion. | 2014 Oct |
6 |
| 37 |
24954906 | Direct binding of Ataxin-2 to distinct elements in 3' UTRs promotes mRNA stability and protein expression. | 2014 Jul 17 |
1 |
| 38 |
25027299 | Insights into the evolution and domain structure of Ataxin-2 proteins across eukaryotes. | 2014 Jul 15 |
3 |
| 39 |
25098532 | Contribution of ATXN2 intermediary polyQ expansions in a spectrum of neurodegenerative disorders. | 2014 Sep 9 |
6 |
| 40 |
22996397 | Spinocerebellar ataxia type 2: clinical presentation, molecular mechanisms, and therapeutic perspectives. | 2013 Feb |
2 |
| 41 |
23172909 | Ataxin-2 interacts with FUS and intermediate-length polyglutamine expansions enhance FUS-related pathology in amyotrophic lateral sclerosis. | 2013 Feb 15 |
1 |
| 42 |
23224816 | Generation of human-induced pluripotent stem cells to model spinocerebellar ataxia type 2 in vitro. | 2013 Oct |
2 |
| 43 |
23735416 | Quantitative profiling and identification of plasma proteins of spinocerebellar ataxia type 2 patients. | 2013 |
1 |
| 44 |
21889984 | The modulation of Amyotrophic Lateral Sclerosis risk by ataxin-2 intermediate polyglutamine expansions is a specific effect. | 2012 Jan |
5 |
| 45 |
22035589 | Ataxin-2 polyQ expansions in FTLD-ALS spectrum disorders in Flanders-Belgian cohorts. | 2012 May |
7 |
| 46 |
22526021 | Distinct TDP-43 pathology in ALS patients with ataxin 2 intermediate-length polyQ expansions. | 2012 Aug |
4 |
| 47 |
22684686 | Brain pathology of spinocerebellar ataxias. | 2012 Jul |
1 |
| 48 |
22764223 | ALS-associated ataxin 2 polyQ expansions enhance stress-induced caspase 3 activation and increase TDP-43 pathological modifications. | 2012 Jul 4 |
8 |
| 49 |
22868089 | ATXN2 with intermediate-length CAG/CAA repeats does not seem to be a risk factor in hereditary spastic paraplegia. | 2012 Oct 15 |
3 |
| 50 |
22916186 | ATXN2 and its neighbouring gene SH2B3 are associated with increased ALS risk in the Turkish population. | 2012 |
9 |