Tryptophan

phenylalanine hydroxylase ; Homo sapiens







10 Article(s)
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Title
Pub. Year
#Total Relationships
1 22112818 START, a double blind, placebo-controlled pharmacogenetic test of responsiveness to sapropterin dihydrochloride in phenylketonuria patients. 2012 Feb 1
2 15060071 Probing the role of crystallographically defined/predicted hinge-bending regions in the substrate-induced global conformational transition and catalytic activation of human phenylalanine hydroxylase by single-site mutagenesis. 2004 Jun 18 1
3 12379147 Substrate-induced conformational transition in human phenylalanine hydroxylase as studied by surface plasmon resonance analyses: the effect of terminal deletions, substrate analogues and phosphorylation. 2003 Feb 1 1
4 11747434 Conformation of the substrate and pterin cofactor bound to human tryptophan hydroxylase. Important role of Phe313 in substrate specificity. 2001 Dec 25 4
5 9022714 Structure/function relationships in human phenylalanine hydroxylase. Effect of terminal deletions on the oligomerization, activation and cooperativity of substrate binding to the enzyme. 1996 Dec 15 3
6 7547912 Tryptophan fluorescence of human phenylalanine hydroxylase produced in Escherichia coli. 1995 Sep 19 6
7 2889273 Assignment of human tryptophan hydroxylase locus to chromosome 11: gene duplication and translocation in evolution of aromatic amino acid hydroxylases. 1987 Sep 1
8 6487579 Spectroscopic investigation of ligand interaction with hepatic phenylalanine hydroxylase: evidence for a conformational change associated with activation. 1984 Aug 14 1
9 5686299 Phenylalanine hydroxylase activity towards two substrates simultaneously: enhancement of inhibition by phenylalanine, tryptophan and their derivatives. 1968 Aug 27 1
10 14491501 Hydroxylation of tryptophan by phenylalanine hydroxylase. 1962 Jul 1