246 Article(s)Download |
PMID | Title | Pub. Year | #Total Relationships |
1 | 34952194 | Phenylalanine hydroxylase (PAH) plays a positive role during WSSV and Vibrio parahaemolyticus infection in Litopenaeus vannamei. | 2022 Jan | 1 |
2 | 35325557 | Evaluation of the Consumption of Fruits and Vegetables by Phenylketonurics in the Metabolic Control of Phenylalanine: An Integrative Review. | 2022 May | 6 |
3 | 35356682 | Development of an mRNA replacement therapy for phenylketonuria. | 2022 Jun 14 | 1 |
4 | 35449354 | Deubiquitinase USP19 enhances phenylalanine hydroxylase protein stability and its enzymatic activity. | 2022 Apr 21 | 2 |
5 | 35600090 | Lipid nanoparticle delivers phenylalanine ammonia lyase mRNA to the liver leading to catabolism and clearance of phenylalanine in a phenylketonuria mouse model. | 2022 Sep | 1 |
6 | 33221376 | Manipulation of a cation-π sandwich reveals conformational flexibility in phenylalanine hydroxylase. | 2021 Apr | 1 |
7 | 33465300 | Phenylketonuria in Portugal: Genotype-phenotype correlations using molecular, biochemical, and haplotypic analyses. | 2021 Mar | 1 |
8 | 33485250 | Adsorption of organic molecules on carbon surfaces: Experimental data and molecular dynamics simulation considering multiple protonation states. | 2021 May | 1 |
9 | 33819046 | Plasma Phospholipidomic Profile Differs between Children with Phenylketonuria and Healthy Children. | 2021 May 7 | 2 |
10 | 34057292 | Pharmacokinetic, pharmacodynamic, and immunogenic rationale for optimal dosing of pegvaliase, a PEGylated bacterial enzyme, in adult patients with phenylketonuria. | 2021 Sep | 1 |
11 | 34145024 | A phosphoproteomic approach reveals that PKD3 controls PKA-mediated glucose and tyrosine metabolism. | 2021 Aug | 1 |
12 | 34162223 | Dysregulated Phenylalanine Catabolism Plays a Key Role in the Trajectory of Cardiac Aging. | 2021 Aug 17 | 2 |
13 | 34207146 | Unravelling the Complex Denaturant and Thermal-Induced Unfolding Equilibria of Human Phenylalanine Hydroxylase. | 2021 Jun 18 | 2 |
14 | 34412683 | A retrospective study on disease management in children and adolescents with phenylketonuria during the Covid-19 pandemic lockdown in Austria. | 2021 Aug 19 | 4 |
15 | 34784942 | Italian national consensus statement on management and pharmacological treatment of phenylketonuria. | 2021 Nov 16 | 3 |
16 | 34819582 | Blood phenylalanine reduction reverses gene expression changes observed in a mouse model of phenylketonuria. | 2021 Nov 24 | 2 |
17 | 34900593 | Untreated PKU patients without intellectual disability: SHANK gene family as a candidate modifier. | 2021 Dec | 1 |
18 | 35082602 | Engineering Organoids for in vitro Modeling of Phenylketonuria. | 2021 | 1 |
19 | 31883647 | 5-year retrospective analysis of patients with phenylketonuria (PKU) and hyperphenylalaninemia treated at two specialized clinics. | 2020 Mar | 4 |
20 | 32106880 | Lower plasma cholesterol, LDL-cholesterol and LDL-lipoprotein subclasses in adult phenylketonuria (PKU) patients compared to healthy controls: results of NMR metabolomics investigation. | 2020 Feb 27 | 3 |
21 | 32217972 | Management of Women With Phenylalanine Hydroxylase Deficiency (Phenylketonuria): ACOG Committee Opinion Summary, Number 802. | 2020 Apr | 1 |
22 | 32450880 | Saccadic reaction time and ocular findings in phenylketonuria. | 2020 May 25 | 1 |
23 | 32668217 | The Genetic Landscape and Epidemiology of Phenylketonuria. | 2020 Aug 6 | 1 |
24 | 32742934 | Unmet needs in PKU and the disease impact on the day-to-day lives in Brazil: Results from a survey with 228 patients and their caregivers. | 2020 Sep | 3 |
25 | 32883979 | Dietary intake and nutritional status of patients with phenylketonuria in Taiwan. | 2020 Sep 3 | 1 |
26 | 33101986 | Phenylketonuria in the Latvian population: Molecular basis, phenylalanine levels, and patient compliance. | 2020 Dec | 3 |
27 | 33260674 | E3 Ubiquitin Ligase APC/CCdh1 Regulation of Phenylalanine Hydroxylase Stability and Function. | 2020 Nov 28 | 1 |
28 | 33335942 | Long-Term Metabolic Correction of Phenylketonuria by AAV-Delivered Phenylalanine Amino Lyase. | 2020 Dec 11 | 1 |
29 | 30504004 | Transient phenylketonuria in premature infants. | 2019 Mar | 2 |
30 | 30648773 | Toward mechanistic models for genotype-phenotype correlations in phenylketonuria using protein stability calculations. | 2019 Apr | 1 |
31 | 30674554 | The phenylketonuria-associated substitution R68S converts phenylalanine hydroxylase to a constitutively active enzyme but reduces its stability. | 2019 Mar 22 | 1 |
32 | 30864096 | Phenylketonuria: Current Treatments and Future Developments. | 2019 Apr | 1 |
33 | 30992364 | Tau repeat regions contain conserved histidine residues that modulate microtubule-binding in response to changes in pH. | 2019 May 31 | 1 |
34 | 31038957 | Uncovered Dynamic Coupling Resolves the Ambiguous Mechanism of Phenylalanine Hydroxylase Oxygen Binding. | 2019 May 30 | 4 |
35 | 31076506 | Biophysical characterization of full-length human phenylalanine hydroxylase provides a deeper understanding of its quaternary structure equilibrium. | 2019 Jun 28 | 2 |
36 | 31105574 | Propagation of Plasma L-Phenylalanine Concentration Fluctuations to the Neurovascular Unit in Phenylketonuria: An in silico Study. | 2019 | 1 |
37 | 31118288 | Structure of full-length human phenylalanine hydroxylase in complex with tetrahydrobiopterin. | 2019 Jun 4 | 2 |
38 | 31434173 | Catalytic Ability Improvement of Phenylalanine Hydroxylase from Chromobacterium violaceum by N-Terminal Truncation and Proline Introduction. | 2019 Sep 28 | 1 |
39 | 29454221 | 13C-phenylalanine breath test and serum biopterin in schizophrenia, bipolar disorder and major depressive disorder. | 2018 Apr | 2 |
40 | 29653686 | Pegvaliase for the treatment of phenylketonuria: Results of a long-term phase 3 clinical trial program (PRISM). | 2018 May | 1 |
41 | 29777816 | Aptamer-based assay for monitoring genetic disorder phenylketonuria (PKU). | 2018 Sep | 1 |
42 | 29909188 | Late-diagnosed phenylketonuria mimicking x-linked adrenoleukodystrophy with heterozygous mutations of the PAH Gene: A case report and literature review. | 2018 Aug | 3 |
43 | 30201326 | A bone mineralization defect in the Pahenu2 model of classical phenylketonuria involves compromised mesenchymal stem cell differentiation. | 2018 Nov | 1 |
44 | 30287685 | Simulations of the regulatory ACT domain of human phenylalanine hydroxylase (PAH) unveil its mechanism of phenylalanine binding. | 2018 Dec 21 | 10 |
45 | 30346142 | Phosphorylation of Phenylalanine Hydroxylase Increases the Rate Constant for Formation of the Activated Conformation of the Enzyme. | 2018 Nov 6 | 2 |
46 | 30578407 | Conformational selection turns on phenylalanine hydroxylase. | 2018 Dec 21 | 1 |
47 | 28174686 | PKU mutation p.G46S prevents the stereospecific binding of l-phenylalanine to the dimer of human phenylalanine hydroxylase regulatory domain. | 2017 Feb | 5 |
48 | 28182360 | Mutation Analysis in Classical Phenylketonuria Patients Followed by Detecting Haplotypes Linked to Some PAH Mutations. | 2017 Feb 1 | 1 |
49 | 28389235 | DNA methylated alleles of the phenylalanine hydroxylase promoter remodeled at elevated phenylalanine levels in newborns with hyperphenylalaninemia. | 2017 Aug | 2 |
50 | 28593914 | Improved metabolic control in tetrahydrobiopterin (BH4), responsive phenylketonuria with sapropterin administered in two divided doses vs. a single daily dose. | 2017 Jul 26 | 1 |