| 51 |
23412628 | Therapeutic targeting malignant mesothelioma with a novel 6-substituted pyrrolo[2,3-d]pyrimidine thienoyl antifolate via its selective uptake by the proton-coupled folate transporter. | 2013 Apr |
1 |
| 52 |
23417011 | Epigenetic alterations in folate transport genes in placental tissue from fetuses with neural tube defects and in leukocytes from subjects with hyperhomocysteinemia. | 2013 Mar |
1 |
| 53 |
23506878 | Folate and thiamine transporters mediated by facilitative carriers (SLC19A1-3 and SLC46A1) and folate receptors. | 2013 Apr-Jun |
3 |
| 54 |
23552283 | Role of the fourth transmembrane domain in proton-coupled folate transporter function as assessed by the substituted cysteine accessibility method. | 2013 Jun 15 |
2 |
| 55 |
23601781 | The monomeric state of the proton-coupled folate transporter represents the functional unit in the plasma membrane. | 2013 Jun |
4 |
| 56 |
23609145 | Inhibition of the proton-coupled folate transporter (PCFT-SLC46A1) by bicarbonate and other anions. | 2013 Jul |
1 |
| 57 |
23816405 | A novel deletion mutation in the proton-coupled folate transporter (PCFT; SLC46A1) in a Nicaraguan child with hereditary folate malabsorption. | 2013 Sep 25 |
3 |
| 58 |
23881211 | The membrane transport and polyglutamation of pralatrexate: a new-generation dihydrofolate reductase inhibitor. | 2013 Sep |
1 |
| 59 |
24205192 | Delineating the extracellular water-accessible surface of the proton-coupled folate transporter. | 2013 |
1 |
| 60 |
24383099 | The proton-coupled folate transporter: physiological and pharmacological roles. | 2013 Dec |
2 |
| 61 |
22179615 | Identification and functional impact of homo-oligomers of the human proton-coupled folate transporter. | 2012 Feb 10 |
3 |
| 62 |
22345511 | A P425R mutation of the proton-coupled folate transporter causing hereditary folate malabsorption produces a highly selective alteration in folate binding. | 2012 May 1 |
4 |
| 63 |
22496243 | Heme carrier protein 1 transports heme and is involved in heme-Fe metabolism. | 2012 Jun 15 |
2 |
| 64 |
22785121 | Identification of a functionally critical GXXG motif and its relationship to the folate binding site of the proton-coupled folate transporter (PCFT-SLC46A1). | 2012 Sep 15 |
5 |
| 65 |
22954694 | The human proton-coupled folate transporter: Biology and therapeutic applications to cancer. | 2012 Dec |
2 |
| 66 |
26105097 | Folate transporter expression decreases in the human placenta throughout pregnancy and in pre-eclampsia. | 2012 Apr |
3 |
| 67 |
21256110 | Vulnerability of the cysteine-less proton-coupled folate transporter (PCFT-SLC46A1) to mutational stress associated with the substituted cysteine accessibility method. | 2011 Apr |
2 |
| 68 |
21346251 | A mouse model of hereditary folate malabsorption: deletion of the PCFT gene leads to systemic folate deficiency. | 2011 May 5 |
1 |
| 69 |
19762432 | The human proton-coupled folate transporter (hPCFT): modulation of intestinal expression and function by drugs. | 2010 Feb |
2 |
| 70 |
20225891 | Membrane topological analysis of the proton-coupled folate transporter (PCFT-SLC46A1) by the substituted cysteine accessibility method. | 2010 Apr 6 |
1 |
| 71 |
20360131 | Mechanism and regulation of folate uptake by pancreatic acinar cells: effect of chronic alcohol consumption. | 2010 Jun |
1 |
| 72 |
20601456 | Targeting the proton-coupled folate transporter for selective delivery of 6-substituted pyrrolo[2,3-d]pyrimidine antifolate inhibitors of de novo purine biosynthesis in the chemotherapy of solid tumors. | 2010 Oct |
1 |
| 73 |
20724482 | The obligatory intestinal folate transporter PCFT (SLC46A1) is regulated by nuclear respiratory factor 1. | 2010 Oct 29 |
3 |
| 74 |
20805364 | Functional roles of aspartate residues of the proton-coupled folate transporter (PCFT-SLC46A1); a D156Y mutation causing hereditary folate malabsorption. | 2010 Dec 9 |
3 |
| 75 |
18823045 | Molecular and functional characteristics of proton-coupled folate transporter. | 2009 May |
5 |
| 76 |
19074442 | A role for the proton-coupled folate transporter (PCFT-SLC46A1) in folate receptor-mediated endocytosis. | 2009 Feb 13 |
3 |
| 77 |
19389703 | The functional roles of the His247 and His281 residues in folate and proton translocation mediated by the human proton-coupled folate transporter SLC46A1. | 2009 Jun 26 |
11 |
| 78 |
19403800 | Role of the glutamate 185 residue in proton translocation mediated by the proton-coupled folate transporter SLC46A1. | 2009 Jul |
5 |
| 79 |
19508863 | Hereditary folate malabsorption: a positively charged amino acid at position 113 of the proton-coupled folate transporter (PCFT/SLC46A1) is required for folic acid binding. | 2009 Aug 28 |
5 |
| 80 |
19666701 | Vitamin D3 and its nuclear receptor increase the expression and activity of the human proton-coupled folate transporter. | 2009 Nov |
3 |
| 81 |
19671745 | Hypermethylation of the human proton-coupled folate transporter (SLC46A1) minimal transcriptional regulatory region in an antifolate-resistant HeLa cell line. | 2009 Aug |
2 |
| 82 |
19740703 | Reversible severe combined immunodeficiency phenotype secondary to a mutation of the proton-coupled folate transporter. | 2009 Dec |
1 |
| 83 |
18003745 | Apical membrane targeting and trafficking of the human proton-coupled transporter in polarized epithelia. | 2008 Jan |
1 |
| 84 |
18256483 | The mechanism of carrier-mediated transport of folates in BeWo cells: the involvement of heme carrier protein 1 in placental folate transport. | 2008 Feb |
3 |
| 85 |
18405659 | N-linked glycosylation and its impact on the electrophoretic mobility and function of the human proton-coupled folate transporter (HsPCFT). | 2008 Jun |
2 |
| 86 |
18559978 | A novel loss-of-function mutation in the proton-coupled folate transporter from a patient with hereditary folate malabsorption reveals that Arg 113 is crucial for function. | 2008 Sep 1 |
2 |
| 87 |
18650265 | Differentiation-dependent regulation of the intestinal folate uptake process: studies with Caco-2 cells and native mouse intestine. | 2008 Sep |
1 |
| 88 |
18776693 | Placental folate transport during pregnancy. | 2008 Sep |
6 |
| 89 |
18817749 | PCFT/SLC46A1 promoter methylation and restoration of gene expression in human leukemia cells. | 2008 Nov 28 |
2 |
| 90 |
18842806 | Associations between single nucleotide polymorphisms in folate uptake and metabolizing genes with blood folate, homocysteine, and DNA uracil concentrations. | 2008 Oct |
2 |
| 91 |
17308042 | Pemetrexed: biochemical and cellular pharmacology, mechanisms, and clinical applications. | 2007 Feb |
2 |
| 92 |
17340171 | The molecular identity and characterization of a Proton-coupled Folate Transporter--PCFT; biological ramifications and impact on the activity of pemetrexed. | 2007 Mar |
1 |
| 93 |
17446347 | The spectrum of mutations in the PCFT gene, coding for an intestinal folate transporter, that are the basis for hereditary folate malabsorption. | 2007 Aug 15 |
1 |
| 94 |
17475902 | Functional characterization of human proton-coupled folate transporter/heme carrier protein 1 heterologously expressed in mammalian cells as a folate transporter. | 2007 Aug |
10 |
| 95 |
17616776 | Effect of folate oversupplementation on folate uptake by human intestinal and renal epithelial cells. | 2007 Jul |
1 |
| 96 |
17898134 | Rodent intestinal folate transporters (SLC46A1): secondary structure, functional properties, and response to dietary folate restriction. | 2007 Nov |
2 |
| 97 |
17129779 | Identification of an intestinal folate transporter and the molecular basis for hereditary folate malabsorption. | 2006 Dec 1 |
2 |