| 1 |
35061292 | The evolving biology of the proton-coupled folate transporter: New insights into regulation, structure, and mechanism. | 2022 Feb |
8 |
| 2 |
35303537 | Structural basis for recognition and transport of folic acid in mammalian cells. | 2022 Jun |
6 |
| 3 |
35561119 | Transporters in drug development: International transporter consortium update on emerging transporters of clinical importance. | 2022 May 13 |
1 |
| 4 |
32820034 | CIC de novo loss of function variants contribute to cerebral folate deficiency by downregulating FOLR1 expression. | 2021 Jul |
3 |
| 5 |
33737637 | Folate transporter dynamics and therapy with classic and tumor-targeted antifolates. | 2021 Mar 18 |
4 |
| 6 |
34040256 | Structural basis of antifolate recognition and transport by PCFT. | 2021 Jul |
4 |
| 7 |
31926453 | Decreased placental folate transporter expression and activity in first and second trimester in obese mothers. | 2020 Mar |
2 |
| 8 |
32154964 | Folate-appended cyclodextrin carrier targets ovarian cancer cells expressing the proton-coupled folate transporter. | 2020 May |
1 |
| 9 |
32295203 | RX-3117 (Fluorocyclopentenyl-Cytosine)-Mediated Down-Regulation of DNA Methyltransferase 1 Leads to Protein Expression of Tumor-Suppressor Genes and Increased Functionality of the Proton-Coupled Folate Carrier. | 2020 Apr 14 |
1 |
| 10 |
32621820 | SLC46A1 contributes to hepatic iron metabolism by importing heme in hepatocytes. | 2020 Sep |
3 |
| 11 |
32893190 | A proton-coupled folate transporter mutation causing hereditary folate malabsorption locks the protein in an inward-open conformation. | 2020 Nov 13 |
2 |
| 12 |
32999198 | [Transfer Mechanisms of Compounds between Mother and Fetus/Infant Aimed for Optimized Medication during Pregnancy and Breastfeeding]. | 2020 |
1 |
| 13 |
30853412 | Decreased expression of folate transport proteins in oral cancer. | 2019 May |
2 |
| 14 |
30858177 | Substitutions that lock and unlock the proton-coupled folate transporter (PCFT-SLC46A1) in an inward-open conformation. | 2019 May 3 |
1 |
| 15 |
30916789 | Cerebral folate deficiency: Analytical tests and differential diagnosis. | 2019 Jul |
1 |
| 16 |
31167838 | Clinical Extrapolation of the Effects of Dolutegravir and Other HIV Integrase Inhibitors on Folate Transport Pathways. | 2019 Aug |
1 |
| 17 |
31223065 | Folate pathway genes linked to mitochondrial biogenesis and respiration are associated with outcome of patients with stage III colorectal cancer. | 2019 Jun |
2 |
| 18 |
31792273 | Identification of the amino acid residue responsible for the myricetin sensitivity of human proton-coupled folate transporter. | 2019 Dec 2 |
3 |
| 19 |
28685492 | Role of Intramuscular Levofolinate Administration in the Treatment of Hereditary Folate Malabsorption: Report of Three Cases. | 2018 |
4 |
| 20 |
29127457 | The promise and challenges of exploiting the proton-coupled folate transporter for selective therapeutic targeting of cancer. | 2018 Jan |
1 |
| 21 |
29167151 | Substituted-cysteine accessibility and cross-linking identify an exofacial cleft in the 7th and 8th helices of the proton-coupled folate transporter (SLC46A1). | 2018 Mar 1 |
3 |
| 22 |
29208467 | Human proton coupled folic acid transporter is a monodisperse oligomer in the lauryl maltose neopentyl glycol solubilized state. | 2018 Jan 8 |
4 |
| 23 |
29223574 | Evaluation of the effects of antiepileptic drugs on folic acid uptake by human placental choriocarcinoma cells. | 2018 Apr |
1 |
| 24 |
29326243 | Concentrative Transport of Antifolates Mediated by the Proton-Coupled Folate Transporter (SLC46A1); Augmentation by a HEPES Buffer. | 2018 Mar |
2 |
| 25 |
29344585 | Hereditary folate malabsorption due to a mutation in the external gate of the proton-coupled folate transporter SLC46A1. | 2018 Jan 9 |
3 |
| 26 |
30063111 | Folate transporter expression in placenta from pregnancies complicated with birth defects. | 2018 Oct 2 |
1 |
| 27 |
27664775 | The proton-coupled folate transporter (PCFT-SLC46A1) and the syndrome of systemic and cerebral folate deficiency of infancy: Hereditary folate malabsorption. | 2017 Feb |
4 |
| 28 |
28138029 | Dual Targeting of Epithelial Ovarian Cancer Via Folate Receptor α and the Proton-Coupled Folate Transporter with 6-Substituted Pyrrolo[2,3-d]pyrimidine Antifolates. | 2017 May |
2 |
| 29 |
28374905 | mTOR folate sensing links folate availability to trophoblast cell function. | 2017 Jul 1 |
4 |
| 30 |
28493963 | Expression in Sf9 insect cells, purification and functional reconstitution of the human proton-coupled folate transporter (PCFT, SLC46A1). | 2017 |
2 |
| 31 |
28592519 | Mechanistic Target of Rapamycin Is a Novel Molecular Mechanism Linking Folate Availability and Cell Function. | 2017 Jul |
2 |
| 32 |
28885847 | Regulation of Reduced Folate Carrier (RFC) by Vitamin D Receptor at the Blood-Brain Barrier. | 2017 Nov 6 |
5 |
| 33 |
26789141 | Evaluation of proton-coupled folate transporter (SLC46A1) polymorphisms as risk factors for neural tube defects and oral clefts. | 2016 Apr |
1 |
| 34 |
26884338 | Identification of an Extracellular Gate for the Proton-coupled Folate Transporter (PCFT-SLC46A1) by Cysteine Cross-linking. | 2016 Apr 8 |
5 |
| 35 |
27023466 | No major effects of vitamin D3 (1,25 dihydroxyvitamin D3) on absorption and pharmacokinetics of folic acid and fexofenadine in healthy volunteers. | 2016 Jul |
2 |
| 36 |
27047750 | Experimentally optimized threading structures of the proton-coupled folate transporter. | 2016 Mar |
2 |
| 37 |
27251438 | Role of the tryptophan residues in proton-coupled folate transporter (PCFT-SLC46A1) function. | 2016 Jul 1 |
2 |
| 38 |
28284395 | Treatable Inborn Errors of Metabolism Due to Membrane Vitamin Transporters Deficiency. | 2016 Nov |
1 |
| 39 |
25564455 | Role of the folate receptor in ovarian cancer treatment: evidence, mechanism, and clinical implications. | 2015 Mar |
2 |
| 40 |
25608532 | Identification of Tyr residues that enhance folate substrate binding and constrain oscillation of the proton-coupled folate transporter (PCFT-SLC46A1). | 2015 Apr 15 |
3 |
| 41 |
25801697 | Sustained inhibition of proton-coupled folate transporter by myricetin. | 2015 Apr |
2 |
| 42 |
25877470 | Structural determinants of human proton-coupled folate transporter oligomerization: role of GXXXG motifs and identification of oligomeric interfaces at transmembrane domains 3 and 6. | 2015 Jul 1 |
1 |
| 43 |
26006721 | CSF 5-Methyltetrahydrofolate Serial Monitoring to Guide Treatment of Congenital Folate Malabsorption Due to Proton-Coupled Folate Transporter (PCFT) Deficiency. | 2015 |
1 |
| 44 |
26403086 | Kinetic and time-dependent features of sustained inhibitory effect of myricetin on folate transport by proton-coupled folate transporter. | 2015 Oct |
1 |
| 45 |
24294939 | Modulation of intestinal folate absorption by erythropoietin in vitro. | 2014 Jan 6 |
2 |
| 46 |
24396145 | The major facilitative folate transporters solute carrier 19A1 and solute carrier 46A1: biology and role in antifolate chemotherapy of cancer. | 2014 Apr |
2 |
| 47 |
24399840 | Macrophage uptake and accumulation of folates are polarization-dependent in vitro and in vivo and are regulated by activin A. | 2014 May |
2 |
| 48 |
24695276 | Effect of epigallocatechin gallate on drug transport mediated by the proton-coupled folate transporter. | 2014 |
1 |
| 49 |
24745983 | Biology of the major facilitative folate transporters SLC19A1 and SLC46A1. | 2014 |
3 |
| 50 |
23313509 | Transcriptional regulation of PCFT by KLF4, HNF4α, CDX2 and C/EBPα: implication in its site-specific expression in the small intestine. | 2013 Feb 8 |
2 |