Guanine Nucleotides

RAB5A, member RAS oncogene family ; Homo sapiens







34 Article(s)
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Pub. Year
#Total Relationships
1 35017116 lncRNA HITT inhibits metastasis by attenuating Rab5-mediated endocytosis in lung adenocarcinoma. 2022 Mar 2 1
2 34243065 The N-terminal intrinsically disordered region mediates intracellular localization and self-oligomerization of ALS2. 2021 Sep 10 1
3 34453711 Profiling Structural Alterations During Rab5 Nucleotide Exchange by HDX-MS. 2021 1
4 34657963 His domain protein tyrosine phosphatase and Rabaptin-5 couple endo-lysosomal sorting of EGFR with endosomal maturation. 2021 Nov 1 1
5 33069695 Role of RIN1 on telomerase activity driven by EGF-Ras mediated signaling in breast cancer. 2020 Nov 15 1
6 33339852 The RabGEF ALS2 is a hypoxia inducible target associated with the acquisition of aggressive traits in tumor cells. 2020 Dec 18 1
7 29314494 Dysregulation of Rab5-mediated endocytic pathways in Alzheimer's disease. 2018 Apr 2
8 28968219 Site-specific monoubiquitination downregulates Rab5 by disrupting effector binding and guanine nucleotide conversion. 2017 Oct 2 1
9 25609093 Rab5-family guanine nucleotide exchange factors bind retromer and promote its recruitment to endosomes. 2015 Mar 15 2
10 25800851 Role of the rab5 guanine nucleotide exchange factor, Rme-6, in the regulation of clathrin-coated vesicle uncoating. 2015 1
11 24569883 Identification of an immune-regulated phagosomal Rab cascade in macrophages. 2014 May 1 1
12 24623720 Dynamic association of the PI3P-interacting Mon1-Ccz1 GEF with vacuoles is controlled through its phosphorylation by the type 1 casein kinase Yck3. 2014 May 1
13 22846990 Rabex-5 protein regulates the endocytic trafficking pathway of ubiquitinated neural cell adhesion molecule L1. 2012 Sep 21 1
14 21586568 Characterization of RIN3 as a guanine nucleotide exchange factor for the Rab5 subfamily GTPase Rab31. 2011 Jul 8 2
15 17239822 ALS2CL, a novel ALS2-interactor, modulates ALS2-mediated endosome dynamics. 2007 Mar 9 1
16 17987124 The redox sensor TXNL1 plays a regulatory role in fluid phase endocytosis. 2007 Nov 7 1
17 16410077 Rab5-activating protein 6, a novel endosomal protein with a role in endocytosis. 2006 Feb 17 1
18 16525121 Varp is a Rab21 guanine nucleotide exchange factor and regulates endosome dynamics. 2006 Mar 15 1
19 16085057 Alsin is partially associated with centrosome in human cells. 2005 Aug 15 1
20 16473597 Purification and functional analyses of ALS2 and its homologue. 2005 3
21 16473603 Capture of the small GTPase Rab5 by GDI: regulation by p38 MAP kinase. 2005 1
22 15023538 Expression of dominant negative rab5 in HeLa cells regulates endocytic trafficking distal from the plasma membrane. 2004 Apr 1 4
23 15033976 Alsin is a Rab5 and Rac1 guanine nucleotide exchange factor. 2004 Jun 4 1
24 15247254 Homo-oligomerization of ALS2 through its unique carboxyl-terminal regions is essential for the ALS2-associated Rab5 guanine nucleotide exchange activity and its regulatory function on endosome trafficking. 2004 Sep 10 1
25 12837691 ALS2, a novel guanine nucleotide exchange factor for the small GTPase Rab5, is implicated in endosomal dynamics. 2003 Jul 15 1
26 11703925 Ras-activated endocytosis is mediated by the Rab5 guanine nucleotide exchange activity of RIN1. 2001 Jul 2
27 10329739 Vps9p is a guanine nucleotide exchange factor involved in vesicle-mediated vacuolar protein transport. 1999 May 21 1
28 9427626 A novel role for Rab5-GDI in ligand sequestration into clathrin-coated pits. 1998 Jan 1 1
29 9852039 Interferon-gamma selectively induces Rab5a synthesis and processing in mononuclear cells. 1998 Dec 18 1
30 7592625 Effect of guanine nucleotide binding on the intrinsic tryptophan fluorescence properties of Rab5. 1995 Oct 13 3
31 7592935 GDP dissociation inhibitor serves as a cytosolic acceptor for newly synthesized and prenylated Rab5. 1995 Nov 10 1
32 7890612 Biochemical and functional characterization of a recombinant GTPase, Rab5, and two of its mutants. 1995 Mar 10 1
33 8226909 Prenylation of Rab5 is dependent on guanine nucleotide binding. 1993 Nov 15 2
34 8226999 Structure-function relationship of the small GTPase rab5. 1993 Nov 15 2