Doxorubicin

ATP binding cassette subfamily C member 3 ; Homo sapiens







48 Article(s)
Download
PMID
Title
Pub. Year
#Total Relationships
1 31926937 Curcumol enhances the sensitivity of doxorubicin in triple-negative breast cancer via regulating the miR-181b-2-3p-ABCC3 axis. 2020 Apr 3
2 28214549 ATP-dependent activity and mitochondrial localization of drug efflux pumps in doxorubicin-resistant breast cancer cells. 2017 May 1
3 28483700 Chemosensitizing indomethacin-conjugated chitosan oligosaccharide nanoparticles for tumor-targeted drug delivery. 2017 Jul 15 4
4 23320839 MEK inhibition induced downregulation of MRP1 and MRP3 expression in experimental hepatocellular carcinoma. 2013 Jan 15 2
5 19732815 Enhancement of doxorubicin concentration in the M5076 ovarian sarcoma cells by cucurbitacin E co-treatment. 2010 Jan 4 3
6 20014242 Stereoselective and multiple carrier-mediated transport of cetirizine across Caco-2 cell monolayers with potential drug interaction. 2010 Jul 1
7 20847343 High levels of Hsp90 cochaperone p23 promote tumor progression and poor prognosis in breast cancer by increasing lymph node metastases and drug resistance. 2010 Nov 1 1
8 19657571 SKP2 siRNA inhibits the degradation of P27kip1 and down-regulates the expression of MRP in HL-60/A cells. 2009 Aug 2
9 18250047 [Detection of multidrug resistance-associated proteins MRP2, MRP3, and MRP5 mRNA expressions in hepatocarcinoma cells using SYBR real-time PCR]. 2008 Feb 1
10 18922976 RhoA silencing reverts the resistance to doxorubicin in human colon cancer cells. 2008 Oct 3
11 15695394 Nitric oxide reverts the resistance to doxorubicin in human colon cancer cells by inhibiting the drug efflux. 2005 Jan 15 4
12 15884115 Drug sensitivity and drug resistance profiles of human intrahepatic cholangiocarcinoma cell lines. 2005 May 14 2
13 15901850 Expression profiling of ABC transporters in a drug-resistant breast cancer cell line using AmpArray. 2005 Aug 1
14 12370750 Reversal of drug resistance using hammerhead ribozymes against multidrug resistance-associated protein and multidrug resistance 1 gene. 2002 Nov 3
15 11290872 Sequential gene expression of P-glycoprotein (P-gp), multidrug resistance-associated protein (MRP) and lung resistance protein: functional activity of P-gp and MRP present in the doxorubicin-resistant human K562 cell lines. 2001 Mar 3
16 11396179 Modulation of multidrug resistance in a cancer cell line by anti-multidrug resistance-associated protein (MRP) ribozyme. 2001 Mar-Apr 2
17 11410522 Multidrug resistance proteins MRP3, MRP1, and MRP2 in lung cancer: correlation of protein levels with drug response and messenger RNA levels. 2001 Jun 2
18 11791127 Resistant mechanisms of anthracyclines--pirarubicin might partly break through the P-glycoprotein-mediated drug-resistance of human breast cancer tissues. 2001 2
19 10736425 Reversal of MRP-mediated doxorubicin resistance with quinoline-based drugs. 2000 May 15 1
20 11078791 Doxorubicin-resistant variants of human prostate cancer cell lines DU 145, PC-3, PPC-1, and TSU-PR1: characterization of biochemical determinants of antineoplastic drug sensitivity. 2000 Dec 1
21 11778274 [Development of drug resistance and alteration of cell cycle in lung cancer: a flow cytometric study]. 2000 Sep 1
22 10100721 Expression of multidrug resistance protein-related genes in lung cancer: correlation with drug response. 1999 Mar 1
23 10348353 Altered expression of the MYCN oncogene modulates MRP gene expression and response to cytotoxic drugs in neuroblastoma cells. 1999 Apr 29 1
24 10364464 Selective potentiation of drug cytotoxicity by NSAID in human glioma cells: the role of COX-1 and MRP. 1999 Jun 16 2
25 10420992 Drug concentration-dependent expression of multidrug resistance-associated protein and P-glycoprotein in the doxorubicin-resistant acute myelogenous leukemia sublines. 1999 Jun 30 3
26 10422816 Expression of the gene for the multidrug resistance-associated protein in human prostate tissue. 1999 Jun 1
27 10533488 Dipyridamole-mediated reversal of multidrug resistance in MRP over-expressing human lung carcinoma cells in vitro. 1999 Jun 1
28 9472628 99mTc-sestamibi is a substrate for P-glycoprotein and the multidrug resistance-associated protein. 1998 1
29 9495245 Co-ordinated over-expression of the MRP and gamma-glutamylcysteine synthetase genes, but not MDR1, correlates with doxorubicin resistance in human malignant mesothelioma cell lines. 1998 Mar 2 3
30 9506530 Development of an intrinsic P-glycoprotein-mediated doxorubicin resistance in quiescent cell layers of large, multicellular prostate tumor spheroids. 1998 Mar 16 2
31 9788569 Lack of correlation of MRP and gamma-glutamylcysteine synthetase overexpression with doxorubicin resistance due to increased apoptosis in SV40 large T-antigen-transformed human mesothelial cells. 1998 3
32 9218735 Characterization of a clonal human colon adenocarcinoma line intrinsically resistant to doxorubicin. 1997 1
33 9334814 Expression of the multidrug resistance-associated protein (MRP) and chemoresistance of human non-small-cell lung cancer cells. 1997 Sep 26 2
34 9359483 Mechanisms for high methoxymorpholino doxorubicin cytotoxicity in doxorubicin-resistant tumor cell lines. 1997 Nov 4 2
35 9406235 Importance of glutathione and associated enzymes in drug response. 1997 1
36 9413193 Multidrug resistance-associated protein gene expression and drug sensitivity in human lung cancer cells. 1997 Sep-Oct 3
37 9477189 Multifactorial involvement of multidrug resistance-associated [correction of resistance] protein, DNA topoisomerase II and glutathione/glutathione-S-transferase in nonP-glycoprotein-mediated multidrug resistance in human bladder cancer cells. 1997 Nov 3
38 8605092 Low-level doxorubicin resistance in P-glycoprotein-negative human pancreatic tumour PSN1/ADR cells implicates a brefeldin A-sensitive mechanism of drug extrusion. 1996 Mar 3
39 8605104 Alterations in expression of the multidrug resistance-associated protein (MRP) gene in high-grade transitional cell carcinoma of the bladder. 1996 Mar 1
40 8626756 Functional expression of the multidrug resistance-associated protein in the yeast Saccharomyces cerevisiae. 1996 Feb 23 3
41 8647646 MRP is frequently expressed in human lung-cancer cell lines, in non-small-cell lung cancer and in normal lungs. 1996 Jun 11 1
42 9045962 The multidrug resistance-associated protein gene confers drug resistance in human gastric and colon cancers. 1996 Dec 1
43 7640209 Altered MRP is associated with multidrug resistance and reduced drug accumulation in human SW-1573 cells. 1995 Aug 1
44 8721085 [Biological features determining the chemosensitivity of gastric cancer]. 1995 Dec 2
45 7825064 Non-P-glycoprotein-mediated multidrug-resistant human KB cells selected in medium containing adriamycin, cepharanthine, and mezerein. 1994 Sep 4
46 7927879 Possible involvement of multidrug-resistance-associated protein (MRP) gene expression in spontaneous drug resistance to vincristine, etoposide and adriamycin in human glioma cells. 1994 Sep 15 4
47 7949184 Expression of the multidrug resistance associated protein and P-glycoprotein in doxorubicin-selected human myeloid leukemia cells. 1994 Nov 1 2
48 8275468 Overexpression of multidrug resistance-associated protein (MRP) increases resistance to natural product drugs. 1994 Jan 15 1