A-1331852

BCL2 like 1 ; Homo sapiens







12 Article(s)
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PMID
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Pub. Year
#Total Relationships
1 35013156 Pediatric multicellular tumor spheroid models illustrate a therapeutic potential by combining BH3 mimetics with Natural Killer (NK) cell-based immunotherapy. 2022 Jan 10 1
2 35074525 Targeting entry into mitochondria for increased anticancer efficacy of BCL-XL-selective inhibitors in lung cancer. 2022 Mar 1
3 35201512 Dual inhibition of anti-apoptotic proteins BCL-XL and MCL-1 enhances cytotoxicity of Nasopharyngeal carcinoma cells. 2022 Feb 3 2
4 35421634 BAK plays a key role in A-1331852-induced apoptosis in senescent chondrocytes. 2022 Jun 18 2
5 34100903 BCL-XL antagonism selectively reduces neutrophil life span within inflamed tissues without causing neutropenia. 2021 Jun 8 1
6 31772331 Potent efficacy of MCL-1 inhibitor-based therapies in preclinical models of mantle cell lymphoma. 2020 Feb 1
7 32346617 Co-inhibition of BCL-XL and MCL-1 with selective BCL-2 family inhibitors enhances cytotoxicity of cervical cancer cell lines. 2020 Jul 2
8 33017468 BCL-XL inhibition by BH3-mimetic drugs induces apoptosis in models of Epstein-Barr virus-associated T/NK-cell lymphoma. 2020 Oct 13 1
9 33062160 Discovery of A-1331852, a First-in-Class, Potent, and Orally-Bioavailable BCL-XL Inhibitor. 2020 Oct 8 2
10 31113936 XPO1 inhibitor KPT-330 synergizes with Bcl-xL inhibitor to induce cancer cell apoptosis by perturbing rRNA processing and Mcl-1 protein synthesis. 2019 May 21 1
11 29928488 Mechanisms for mTORC1 activation and synergistic induction of apoptosis by ruxolitinib and BH3 mimetics or autophagy inhibitors in JAK2-V617F-expressing leukemic cells including newly established PVTL-2. 2018 Jun 1 2
12 26939706 Expression Profile of BCL-2, BCL-XL, and MCL-1 Predicts Pharmacological Response to the BCL-2 Selective Antagonist Venetoclax in Multiple Myeloma Models. 2016 May 2