| 1 |
30846494 | Histone deacetylase inhibition in combination with MEK or BCL-2 inhibition in multiple myeloma. | 2019 Oct |
1 |
| 2 |
31059787 | BCL-XL directly retrotranslocates the monomeric BAK. | 2019 Sep |
11 |
| 3 |
28511583 | Deciphering the crucial residues involved in heterodimerization of Bak peptide and anti-apoptotic proteins for apoptosis. | 2018 May |
1 |
| 4 |
28750564 | Selective Antagonism of Bcl-xL Potentiates M1 Oncolysis by Enhancing Mitochondrial Apoptosis. | 2018 Aug |
1 |
| 5 |
29233828 | E2F1 interacts with BCL-xL and regulates its subcellular localization dynamics to trigger cell death. | 2018 Feb |
1 |
| 6 |
30308410 | Structure-guided design of pyridoclax derivatives based on Noxa / Mcl-1 interaction mode. | 2018 Nov 5 |
1 |
| 7 |
30309889 | BH3-mimetic toolkit guides the respective use of BCL2 and MCL1 BH3-mimetics in myeloma treatment. | 2018 Dec 20 |
1 |
| 8 |
26996126 | Cisplatin-induced apoptosis in non-small-cell lung cancer cells is dependent on Bax- and Bak-induction pathway and synergistically activated by BH3-mimetic ABT-263 in p53 wild-type and mutant cells. | 2016 Apr 29 |
1 |
| 9 |
26606906 | Targeting cholesterol with β-cyclodextrin sensitizes cancer cells for apoptosis. | 2015 Dec 21 |
1 |
| 10 |
26610208 | In non-transformed cells Bak activates upon loss of anti-apoptotic Bcl-XL and Mcl-1 but in the absence of active BH3-only proteins. | 2015 Nov 26 |
1 |
| 11 |
24337869 | Synergistic induction of apoptosis in A549 cells by dihydroartemisinin and gemcitabine. | 2014 Apr |
2 |
| 12 |
23887890 | Gamma-secretase inhibition attenuates oxaliplatin-induced apoptosis through increased Mcl-1 and/or Bcl-xL in human colon cancer cells. | 2013 Oct |
1 |
| 13 |
22395339 | Relaxation of the rigid backbone of an oligoamide-foldamer-based α-helix mimetic: identification of potent Bcl-xL inhibitors. | 2012 Apr 21 |
1 |
| 14 |
21528891 | Rational design of new class of BH3-mimetics as inhibitors of the Bcl-xL protein. | 2011 Jun 27 |
1 |
| 15 |
21533126 | The anti-apoptotic Bcl-x(L) protein, a new piece in the puzzle of cytochrome c interactome. | 2011 Apr 18 |
1 |
| 16 |
21807395 | Synthesis and molecular modeling study of new trimeric quinoline derivatives. | 2011 Aug |
2 |
| 17 |
20229565 | Isolation of a small-molecule inhibitor of the antiapoptotic protein Bcl-xL from a DNA-encoded chemical library. | 2010 Apr 6 |
1 |
| 18 |
19349174 | Induction of apoptosis promoted by Bang52; a small molecule that downregulates Bcl-x(L). | 2009 May 1 |
1 |
| 19 |
17692431 | Structure-activity relationships of Bak derived peptides: affinity and specificity modulations by amino acid replacement. | 2008 May |
1 |
| 20 |
18603801 | A new assay based on fluorescence resonance energy transfer to determine the binding affinity of Bcl-xL inhibitors. | 2008 Jul |
2 |
| 21 |
17652400 | Evidence for involvement of BH3-only proapoptotic members in adenovirus-induced apoptosis. | 2007 Oct |
1 |
| 22 |
17692289 | Oligomerization of BH4-truncated Bcl-x(L) in solution. | 2007 Oct 5 |
1 |
| 23 |
16794010 | Bcl-xL is overexpressed in hormone-resistant prostate cancer and promotes survival of LNCaP cells via interaction with proapoptotic Bak. | 2006 Oct |
7 |
| 24 |
14683437 | Data reduction methods for application of fluorescence correlation spectroscopy to pharmaceutical drug discovery. | 2003 Dec |
1 |
| 25 |
11713097 | Histone deacetylase inhibitor downregulation of bcl-xl gene expression leads to apoptotic cell death in mesothelioma. | 2001 Nov |
1 |
| 26 |
10085290 | Cell damage-induced conformational changes of the pro-apoptotic protein Bak in vivo precede the onset of apoptosis. | 1999 Mar 8 |
3 |
| 27 |
10089877 | Solution structure of BID, an intracellular amplifier of apoptotic signaling. | 1999 Mar 5 |
4 |