Imatinib Mesylate

BCL2 like 1 ; Homo sapiens







22 Article(s)
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1 28319085 Synergistic drug combinations for cancer identified in a CRISPR screen for pairwise genetic interactions. 2017 May 1
2 26987906 High CIP2A levels correlate with an antiapoptotic phenotype that can be overcome by targeting BCL-XL in chronic myeloid leukemia. 2016 Jun 1
3 26473951 Knockout Serum Replacement Promotes Cell Survival by Preventing BIM from Inducing Mitochondrial Cytochrome C Release. 2015 1
4 24088895 Activin A induction of erythroid differentiation sensitizes K562 chronic myeloid leukemia cells to a subtoxic concentration of imatinib. 2014 Jan 1 1
5 24504921 Ageing is a risk factor in imatinib mesylate cardiotoxicity. 2014 Apr 1
6 23613979 Aclacinomycin A sensitizes K562 chronic myeloid leukemia cells to imatinib through p38MAPK-mediated erythroid differentiation. 2013 1
7 22211240 Alternative splicing of apoptosis-related genes in imatinib-treated K562 cells identified by exon array analysis. 2012 Apr 1
8 21115411 Synergistic induction of apoptosis by the Bcl-2 inhibitor ABT-737 and imatinib mesylate in gastrointestinal stromal tumor cells. 2011 Feb 2
9 20094798 Enhancement of imatinib-induced apoptosis of BCR/ABL-expressing cells by nutlin-3 through synergistic activation of the mitochondrial apoptotic pathway. 2010 May 1
10 20723293 [Effects of STI571 combined with As₂O₃ on proliferation, apoptosis and caspase 3, Bcl-xL expression of K562 cells]. 2010 Aug 3
11 19934315 Imatinib mesylate induces cisplatin hypersensitivity in Bcr-Abl+ cells by differential modulation of p53 transcriptional and proapoptotic activity. 2009 Dec 15 1
12 17420275 GATA-1 and Gfi-1B interplay to regulate Bcl-xL transcription. 2007 Jun 1
13 17545631 BCR-ABL activity is critical for the immunogenicity of chronic myelogenous leukemia cells. 2007 Jun 1 1
14 17926190 (-)Gossypol and its combination with imatinib induce apoptosis in human chronic myeloid leukemic cells. 2007 Nov 1
15 18088462 [STI571 induces apoptosis of K562 cells through down-regulation of anti-apoptotic protein Mcl-1 and Bcl-xl expression]. 2007 Dec 3
16 15039284 Bortezomib and flavopiridol interact synergistically to induce apoptosis in chronic myeloid leukemia cells resistant to imatinib mesylate through both Bcr/Abl-dependent and -independent mechanisms. 2004 Jul 15 1
17 11782377 Pharmacologic mitogen-activated protein/extracellular signal-regulated kinase kinase/mitogen-activated protein kinase inhibitors interact synergistically with STI571 to induce apoptosis in Bcr/Abl-expressing human leukemia cells. 2002 Jan 1 1
18 12231544 Flavopiridol potentiates STI571-induced mitochondrial damage and apoptosis in BCR-ABL-positive human leukemia cells. 2002 Sep 1
19 11179439 The catalytic DNA topoisomerase II inhibitor dexrazoxane (ICRF-187) induces differentiation and apoptosis in human leukemia K562 cells. 2001 Mar 1
20 11313280 Down-regulation of interleukin-3/granulocyte-macrophage colony-stimulating factor receptor beta-chain in BCR-ABL(+) human leukemic cells: association with loss of cytokine-mediated Stat-5 activation and protection from apoptosis after BCR-ABL inhibition. 2001 May 1 1
21 11368438 Co-treatment with As2O3 enhances selective cytotoxic effects of STI-571 against Brc-Abl-positive acute leukemia cells. 2001 May 1
22 10815921 The tyrosine kinase inhibitor CGP 57148 (ST1 571) induces apoptosis in BCR-ABL-positive cells by down-regulating BCL-X. 2000 May 1