Cisplatin

BCL2 like 1 ; Homo sapiens







109 Article(s)
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51 20477830 KIAA0495/PDAM is frequently downregulated in oligodendroglial tumors and its knockdown by siRNA induces cisplatin resistance in glioma cells. 2010 Nov 1
52 20619636 Aven blocks DNA damage-induced apoptosis by stabilising Bcl-xL. 2010 Sep 1
53 22545969 Evaluation of cisplatin in combination with β-elemene as a regimen for prostate cancer chemotherapy. 2010 Nov 1
54 19240170 Bcl-2 blocks cisplatin-induced apoptosis and predicts poor outcome following chemoradiation treatment in advanced oropharyngeal squamous cell carcinoma. 2009 Mar 1 1
55 19317621 The role of Bcl-x(L) protein in nucleotide excision repair-facilitated cell protection against cisplatin-induced apoptosis. 2009 Jun 7
56 19328230 Cisplatin-induced nitrosylation of p53 prevents its mitochondrial translocation. 2009 Jun 15 1
57 19414365 Clock gene mouse period2 overexpression inhibits growth of human pancreatic cancer cells and has synergistic effect with cisplatin. 2009 Apr 1
58 19578044 Cisplatin overcomes Bcl-2-mediated resistance to apoptosis via preferential engagement of Bak: critical role of Noxa-mediated lipid peroxidation. 2009 Sep 1
59 19887550 Mcl-1 is an important determinant of the apoptotic response to the BH3-mimetic molecule HA14-1 in cisplatin-resistant ovarian carcinoma cells. 2009 Nov 1
60 19934315 Imatinib mesylate induces cisplatin hypersensitivity in Bcr-Abl+ cells by differential modulation of p53 transcriptional and proapoptotic activity. 2009 Dec 15 2
61 18376141 Anti-oxidant treatment enhances anti-tumor cytotoxicity of (-)-gossypol. 2008 May 3
62 18451495 Berberine, a natural product, combined with cisplatin enhanced apoptosis through a mitochondria/caspase-mediated pathway in HeLa cells. 2008 May 1
63 18566236 Bortezomib induces apoptosis via Bim and Bik up-regulation and synergizes with cisplatin in the killing of head and neck squamous cell carcinoma cells. 2008 Jun 1
64 18585380 Inhibition of mTOR restores cisplatin sensitivity through down-regulation of growth and anti-apoptotic proteins. 2008 Sep 4 1
65 17275076 Absence of Bcl-xL down-regulation in response to cisplatin is associated with chemoresistance in ovarian carcinoma cells. 2007 Apr 6
66 17311906 Mcl-1 is downregulated in cisplatin-induced apoptosis, and proteasome inhibitors restore Mcl-1 and promote survival in renal tubular epithelial cells. 2007 Jun 1
67 17383050 Taurolidine and povidone-iodine induce different types of cell death in malignant pleural mesothelioma. 2007 Jun 1
68 17399942 Characterization of cell death events induced by anti-neoplastic drugs cisplatin, paclitaxel and 5-fluorouracil on human hepatoma cell lines: Possible mechanisms of cell resistance. 2007 Jul 2
69 17492131 Bcl-XL small interfering RNA sensitizes cisplatin-resistant human lung adenocarcinoma cells. 2007 May 1
70 17619073 Solamargine induces apoptosis and sensitizes breast cancer cells to cisplatin. 2007 Nov 3
71 17848273 Targeting apoptosis to overcome cisplatin resistance: a translational study in head and neck cancer. 2007 5
72 18059167 Inhibition of Stat3 activity by YC-1 enhances chemo-sensitivity in hepatocellular carcinoma. 2007 Dec 1
73 16188300 Bcl-X(L) is functionally non-equivalent for the regulation of growth and survival in human ovarian cancer cells. 2006 Feb 1
74 16331250 Involvement of Bcl-X(L) deamidation in E1A-mediated cisplatin sensitization of ovarian cancer cells. 2006 Apr 27 3
75 16424027 Cisplatin mimics ARF tumor suppressor regulation of RelA (p65) nuclear factor-kappaB transactivation. 2006 Jan 15 3
76 16442262 Role of death receptor and mitochondrial pathways in conventional chemotherapy drug induction of apoptosis. 2006 Sep 1
77 16525642 Antitumor effects of the novel NF-kappaB inhibitor dehydroxymethyl-epoxyquinomicin on human hepatic cancer cells: analysis of synergy with cisplatin and of possible correlation with inhibition of pro-survival genes and IL-6 production. 2006 Apr 1
78 16533421 Increased sensitivity to cisplatin in non-small cell lung cancer cell lines after FHIT gene transfer. 2006 Jan 1
79 16549753 Cisplatin-induced growth arrest of head and neck cancer cells correlates with increased expression of p16 and p53. 2006 Mar 1
80 15661210 Expression of Bcl-xL in ovarian carcinoma is associated with chemoresistance and recurrent disease. 2005 Feb 2
81 15958577 Expression of Siva-1 protein or its putative amphipathic helical region enhances cisplatin-induced apoptosis in breast cancer cells: effect of elevated levels of BCL-2. 2005 Jun 15 1
82 16020667 Reversal of cisplatin resistance with a BH3 mimetic, (-)-gossypol, in head and neck cancer cells: role of wild-type p53 and Bcl-xL. 2005 Jul 3
83 16115953 Overexpression of cyclin D1 promotes tumor cell growth and confers resistance to cisplatin-mediated apoptosis in an elastase-myc transgene-expressing pancreatic tumor cell line. 2005 Aug 15 1
84 15010843 Modulation of Janus kinase 2 by cisplatin in cancer cells. 2004 Apr 1
85 15026553 Down-regulation of Bcl-2 is associated with cisplatin resistance in human small cell lung cancer H69 cells. 2004 Mar 1
86 15141012 Antisense oligonucleotides directed at the bcl-xl gene product augment chemotherapy response in mesothelioma. 2004 May 1
87 15156398 Resistance to chemotherapy-induced apoptosis via decreased caspase-3 activity and overexpression of antiapoptotic proteins in ovarian cancer. 2004 Jul 1
88 15315167 Difference in expression of Bcl-2 and Bcl-xl genes in cisplatin-sensitive and cisplatin-resistant human in ovarian cancer cell lines. 2004 4
89 15375532 Angiotensin II activates MAP kinase and NF-kappaB through angiotensin II type I receptor in human pancreatic cancer cells. 2004 Oct 2
90 15566959 Dual apoptotic effect of Xrel3 c-Rel/NF-kappaB homolog in human cervical cancer cells. 2004 1
91 12536078 Physiological and molecular effects of Apo2L/TRAIL and cisplatin in ovarian carcinoma cell lines. 2003 Feb 10 1
92 12950722 Genistein enhances the cisplatin-induced inhibition of cell growth and apoptosis in human malignant melanoma cells. 2003 Oct 1
93 11734333 Induction of apoptosis by cisplatin and its effect on cell cycle-related proteins and cell cycle changes in hepatoma cells. 2002 Jan 10 1
94 11857368 Overexpression of BclXL in a human ovarian carcinoma cell line: paradoxic effects on chemosensitivity in vitro versus in vivo. 2002 Feb 20 4
95 11948488 Bcl-X(L) is a chemoresistance factor in human melanoma cells that can be inhibited by antisense therapy. 2002 May 1 1
96 12667321 [Relationship between cytochrome c-mediated caspase-3 activity and chemoresistance in cisplatin-resistant human ovarian cancer cell lines]. 2002 Nov 6
97 11368186 Targeting superoxide dismutase to renal proximal tubule cells inhibits mitochondrial injury and renal dysfunction inuduced by cisplatin. 2001 Mar 1 1
98 11384107 Telomerase activity and p53-dependent apoptosis in ovarian cancer cells. 2001 Jun 1 1
99 10974635 Sensitivity to paclitaxel is not related to p53-dependent apoptosis in ovarian cancer cells. 2000 Sep 1
100 10397248 Cisplatin-induced apoptosis proceeds by caspase-3-dependent and -independent pathways in cisplatin-resistant and -sensitive human ovarian cancer cell lines. 1999 Jul 1 1