| 151 |
17452531 | Mitochondrial permeabilization relies on BH3 ligands engaging multiple prosurvival Bcl-2 relatives, not Bak. | 2007 Apr 23 |
1 |
| 152 |
17460700 | ABT-737, an inhibitor of Bcl-2 family proteins, is a potent inducer of apoptosis in multiple myeloma cells. | 2007 Jul |
1 |
| 153 |
17503422 | Exploration of backbone space in foldamers containing alpha- and beta-amino acid residues: developing protease-resistant oligomers that bind tightly to the BH3-recognition cleft of Bcl-xL. | 2007 May 25 |
2 |
| 154 |
17597151 | Modeling backbone flexibility to achieve sequence diversity: the design of novel alpha-helical ligands for Bcl-xL. | 2007 Aug 24 |
2 |
| 155 |
16288206 | A novel Bcl-x splice product, Bcl-xAK, triggers apoptosis in human melanoma cells without BH3 domain. | 2006 Apr 6 |
1 |
| 156 |
16728570 | Beyond peroxisome proliferator-activated receptor gamma signaling: the multi-facets of the antitumor effect of thiazolidinediones. | 2006 Jun |
1 |
| 157 |
16826547 | NMR determination that an extended BH3 motif of pro-apoptotic BID is specifically bound to BCL-XL. | 2006 Jul |
1 |
| 158 |
17011577 | Chelerythrine and sanguinarine dock at distinct sites on BclXL that are not the classic BH3 binding cleft. | 2006 Dec 1 |
3 |
| 159 |
17052454 | A stapled BID BH3 helix directly binds and activates BAX. | 2006 Oct 20 |
1 |
| 160 |
18221044 | Mitocans: mitochondrial targeted anti-cancer drugs as improved therapies and related patent documents. | 2006 Nov |
1 |
| 161 |
15826183 | Terephthalamide derivatives as mimetics of helical peptides: disruption of the Bcl-x(L)/Bak interaction. | 2005 Apr 20 |
1 |
| 162 |
16020667 | Reversal of cisplatin resistance with a BH3 mimetic, (-)-gossypol, in head and neck cancer cells: role of wild-type p53 and Bcl-xL. | 2005 Jul |
1 |
| 163 |
16054143 | A new assay for the discovery of Bcl-XL inhibitors. | 2005 Nov-Dec |
1 |
| 164 |
14960327 | Defining the p53 DNA-binding domain/Bcl-x(L)-binding interface using NMR. | 2004 Feb 13 |
1 |
| 165 |
15008953 | Proteins of the bcl-2 family in apoptosis signalling: from mechanistic insights to therapeutic opportunities. | 2004 Mar |
1 |
| 166 |
15131699 | Bcl-x(L) sequesters its C-terminal membrane anchor in soluble, cytosolic homodimers. | 2004 May 19 |
1 |
| 167 |
15570010 | In vitro effects of the BH3 mimetic, (-)-gossypol, on head and neck squamous cell carcinoma cells. | 2004 Nov 15 |
1 |
| 168 |
12694257 | BH3-domain mimetic compound BH3I-2' induces rapid damage to the inner mitochondrial membrane prior to the cytochrome c release from mitochondria. | 2003 Apr |
1 |
| 169 |
11964315 | Erythrocyte survival is promoted by plasma and suppressed by a Bak-derived BH3 peptide that interacts with membrane-associated Bcl-X(L). | 2002 May 1 |
1 |
| 170 |
12135371 | Peptides derived from BH3 domains of Bcl-2 family members: a comparative analysis of inhibition of Bcl-2, Bcl-x(L) and Bax oligomerization, induction of cytochrome c release, and activation of cell death. | 2002 Jul 30 |
4 |
| 171 |
11175750 | Identification of small-molecule inhibitors of interaction between the BH3 domain and Bcl-xL. | 2001 Feb |
2 |
| 172 |
11175751 | Antimycin A mimics a cell-death-inducing Bcl-2 homology domain 3. | 2001 Feb |
1 |
| 173 |
11583631 | BCL-2, BCL-X(L) sequester BH3 domain-only molecules preventing BAX- and BAK-mediated mitochondrial apoptosis. | 2001 Sep |
1 |
| 174 |
11687955 | Killing of sarcoma cells by proapoptotic Bcl-X(S): role of the BH3 domain and regulation by Bcl-X(L). | 2001 Sep-Oct |
2 |
| 175 |
11728179 | Discovery of small-molecule inhibitors of Bcl-2 through structure-based computer screening. | 2001 Dec 6 |
1 |
| 176 |
10089877 | Solution structure of BID, an intracellular amplifier of apoptotic signaling. | 1999 Mar 5 |
6 |
| 177 |
10224090 | Bak BH3 peptides antagonize Bcl-xL function and induce apoptosis through cytochrome c-independent activation of caspases. | 1999 May 7 |
1 |
| 178 |
10490606 | The BH3 domain of Bcl-x(S) is required for inhibition of the antiapoptotic function of Bcl-x(L). | 1999 Oct |
2 |
| 179 |
9575197 | Adenovirus E1B-19K/BCL-2 interacting protein BNIP3 contains a BH3 domain and a mitochondrial targeting sequence. | 1998 May 15 |
1 |
| 180 |
9130713 | harakiri, a novel regulator of cell death, encodes a protein that activates apoptosis and interacts selectively with survival-promoting proteins Bcl-2 and Bcl-X(L). | 1997 Apr 1 |
1 |
| 181 |
8798452 | Bax can antagonize Bcl-XL during etoposide and cisplatin-induced cell death independently of its heterodimerization with Bcl-XL. | 1996 Sep 13 |
1 |