Curcumin

BCL2 like 1 ; Homo sapiens







55 Article(s)
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1 32021103 Curcumin Combined with Thalidomide Reduces Expression of STAT3 and Bcl-xL, Leading to Apoptosis in Acute Myeloid Leukemia Cell Lines. 2020 3
2 32141025 Curcumin augments therapeutic efficacy of TRAIL-based immunotoxins in leukemia. 2020 Aug 1
3 32515250 Curcumin potentiates laryngeal squamous carcinoma radiosensitivity via NF-ΚB inhibition by suppressing IKKγ expression. 2020 Dec 1
4 33178666 Enhancing Bioavailability and Stability of Curcumin Using Solid Lipid Nanoparticles (CLEN): A Covenant for Its Effectiveness. 2020 1
5 28861154 Curcumin inhibits human non-small cell lung cancer xenografts by targeting STAT3 pathway. 2017 2
6 29245915 Curcumin interacts with sildenafil to kill GI tumor cells via endoplasmic reticulum stress and reactive oxygen/ nitrogen species. 2017 Nov 21 1
7 27779649 Effect of curcumin and paclitaxel on breast carcinogenesis. 2016 Dec 1
8 26232616 Ceramide generation during curcumin-induced apoptosis is controlled by crosstalk among Bcl-2, Bcl-xL, caspases and glutathione. 2015 Nov 2
9 23451189 Curcumin enhances the effect of chemotherapy against colorectal cancer cells by inhibition of NF-κB and Src protein kinase signaling pathways. 2013 1
10 24079252 [Study on functions and mechanism of curcumin in inducing colorectal carcinoma cells LoVo apoptosis]. 2013 Jul 1
11 21711158 Curcumin induces small cell lung cancer NCI-H446 cell apoptosis via the reactive oxygen species-mediated mitochondrial pathway and not the cell death receptor pathway. 2012 Feb 1
12 21775121 The curry spice curcumin selectively inhibits cancer cells growth in vitro and in preclinical model of glioblastoma. 2012 Jun 1
13 22498762 Curcumin induces apoptosis in tumor necrosis factor-alpha-treated HaCaT cells. 2012 Jun 1
14 22508043 Trolox enhances curcumin's cytotoxicity through induction of oxidative stress. 2012 1
15 22562377 Involvement of NF-κB activation in the cisplatin resistance of human epidermoid carcinoma KCP-4 cells. 2012 Jul 1
16 22653966 Oxidative stress induced by curcumin promotes the death of cutaneous T-cell lymphoma (HuT-78) by disrupting the function of several molecular targets. 2012 Sep 1
17 22944278 [Curcumin inhibits iron overload-induced hepatocytic apoptosis and nuclear factor-κB activity]. 2012 Jul 24 1
18 21704149 Dietary phytochemicals induce p53- and caspase-independent cell death in human neuroblastoma cells. 2011 Nov 1
19 21857083 No protective effect of curcumin on hydrogen peroxide-induced cytotoxicity in HepG2 cells. 2011 1
20 20332461 Curcumin (diferuloylmethane) induces apoptosis and blocks migration of human medulloblastoma cells. 2010 Feb 1
21 20416164 [Apoptosis of retinoic acid resistant NB4-R1 cells induced with curcumin and its mechanism]. 2010 Apr 1
22 20429876 Curcumin induces chemo/radio-sensitization in ovarian cancer cells and curcumin nanoparticles inhibit ovarian cancer cell growth. 2010 Apr 29 1
23 20450049 [Anticancer activities of curcumin on human hepatocarcinoma cell line Sk-hep-1]. 2010 Feb 1
24 20521051 C6 ceramide potentiates curcumin-induced cell death and apoptosis in melanoma cell lines in vitro. 2010 Oct 1
25 20651361 Curcumin induces apoptosis in human non-small cell lung cancer NCI-H460 cells through ER stress and caspase cascade- and mitochondria-dependent pathways. 2010 Jun 1
26 20661831 Distinct combinatorial effects of the plant polyphenols curcumin, carnosic acid, and silibinin on proliferation and apoptosis in acute myeloid leukemia cells. 2010 1
27 20726007 Curcumin in cancer chemoprevention: molecular targets, pharmacokinetics, bioavailability, and clinical trials. 2010 Sep 1
28 21036715 Curcumin-altered p53-response genes regulate radiosensitivity in p53-mutant Ewing's sarcoma cells. 2010 Oct 1
29 19191010 Molecular mechanism of curcumin induced cytotoxicity in human cervical carcinoma cells. 2009 May 1
30 19235267 Curcumin induces apoptosis through the mitochondria-mediated apoptotic pathway in HT-29 cells. 2009 Feb 2
31 19250217 Curcumin as a possible lead compound against hormone-independent, multidrug-resistant breast cancer. 2009 Feb 1
32 19372569 Curcumin circumvents chemoresistance in vitro and potentiates the effect of thalidomide and bortezomib against human multiple myeloma in nude mice model. 2009 Apr 1
33 19735878 Curcumin modulates the radiosensitivity of colorectal cancer cells by suppressing constitutive and inducible NF-kappaB activity. 2009 Oct 1 1
34 19889203 Synergistic chondroprotective effects of curcumin and resveratrol in human articular chondrocytes: inhibition of IL-1beta-induced NF-kappaB-mediated inflammation and apoptosis. 2009 1
35 18386790 Curcumin induces cell-arrest and apoptosis in association with the inhibition of constitutively active NF-kappaB and STAT3 pathways in Hodgkin's lymphoma cells. 2008 Jul 1 1
36 17148446 Curcumin suppresses AP1 transcription factor-dependent differentiation and activates apoptosis in human epidermal keratinocytes. 2007 Mar 2 1
37 17289836 Curcumin [1,7-bis(4-hydroxy-3-methoxyphenyl)-1-6-heptadine-3,5-dione; C21H20O6] sensitizes human prostate cancer cells to tumor necrosis factor-related apoptosis-inducing ligand/Apo2L-induced apoptosis by suppressing nuclear factor-kappaB via inhibition of the prosurvival Akt signaling pathway. 2007 May 2
38 17640567 Role of pro-oxidants and antioxidants in the anti-inflammatory and apoptotic effects of curcumin (diferuloylmethane). 2007 Aug 15 1
39 17671737 The antitumor activities of curcumin and of its isoxazole analogue are not affected by multiple gene expression changes in an MDR model of the MCF-7 breast cancer cell line: analysis of the possible molecular basis. 2007 Sep 2
40 16376585 Antiproliferation and apoptosis induced by curcumin in human ovarian cancer cells. 2006 Mar 2
41 16628653 Notch-1 down-regulation by curcumin is associated with the inhibition of cell growth and the induction of apoptosis in pancreatic cancer cells. 2006 Jun 1 1
42 15661804 Human colon cancer cells lacking Bax resist curcumin-induced apoptosis and Bax requirement is dispensable with ectopic expression of Smac or downregulation of Bcl-XL. 2005 Apr 1
43 15911101 Antitumor effects of curcumin, alone or in combination with cisplatin or doxorubicin, on human hepatic cancer cells. Analysis of their possible relationship to changes in NF-kB activation levels and in IAP gene expression. 2005 Jun 16 2
44 16173963 Effects of nuclear factor-kappaB inhibitors and its implication on natural killer T-cell lymphoma cells. 2005 Oct 1
45 16243823 Curcumin suppresses the paclitaxel-induced nuclear factor-kappaB pathway in breast cancer cells and inhibits lung metastasis of human breast cancer in nude mice. 2005 Oct 15 1
46 16302093 Curcumin induces human HT-29 colon adenocarcinoma cell apoptosis by activating p53 and regulating apoptosis-related protein expression. 2005 Dec 1
47 15142674 Induction of apoptosis in human lung cancer cells by curcumin. 2004 May 28 1
48 15205359 Ectopic expression of Bcl-XL or Ku70 protects human colon cancer cells (SW480) against curcumin-induced apoptosis while their down-regulation potentiates it. 2004 Oct 3
49 12393461 Curcumin (diferuloylmethane) down-regulates the constitutive activation of nuclear factor-kappa B and IkappaBalpha kinase in human multiple myeloma cells, leading to suppression of proliferation and induction of apoptosis. 2003 Feb 1 1
50 12684045 Ruthenium red, inhibitor of mitochondrial Ca2+ uniporter, inhibits curcumin-induced apoptosis via the prevention of intracellular Ca2+ depletion and cytochrome c release. 2003 Apr 18 1