| 1 |
35014203 | A case study of a patient-centered reverse translational systems-based approach to understand adverse event profiles in drug development. | 2022 Apr |
1 |
| 2 |
35216449 | Employing CRISPR-Cas9 to Generate CD133 Synthetic Lethal Melanoma Stem Cells. | 2022 Feb 20 |
1 |
| 3 |
35526324 | Bcl-xL is required for the protective effects of low-dose berberine against doxorubicin-induced cardiotoxicity through blocking apoptosis and activating mitophagy-mediated ROS elimination. | 2022 Jul |
1 |
| 4 |
32944866 | Anticancer activity and evaluation of apoptotic genes expression of 2-azetidinones containing anthraquinone moiety. | 2021 Nov |
1 |
| 5 |
34190523 | Co-administration of apigenin with doxorubicin enhances anti-migration and antiproliferative effects via PI3K/PTEN/AKT pathway in prostate cancer cells. | 2021 Jun |
1 |
| 6 |
34608124 | Severe cellular stress activates apoptosis independently of p53 in osteosarcoma. | 2021 Oct 4 |
1 |
| 7 |
32340377 | Arctigenin Enhances the Cytotoxic Effect of Doxorubicin in MDA-MB-231 Breast Cancer Cells. | 2020 Apr 23 |
1 |
| 8 |
32396934 | IKAROS and CK2 regulate expression of BCL-XL and chemosensitivity in high-risk B-cell acute lymphoblastic leukemia. | 2020 Sep 24 |
1 |
| 9 |
32801295 | Sequential combinations of chemotherapeutic agents with BH3 mimetics to treat rhabdomyosarcoma and avoid resistance. | 2020 Aug 15 |
1 |
| 10 |
28947136 | BCL-xL-selective BH3 mimetic sensitizes rhabdomyosarcoma cells to chemotherapeutics by activation of the mitochondrial pathway of apoptosis. | 2018 Jan 1 |
1 |
| 11 |
29329420 | Pyrrolidine dithiocarbamate reverses Bcl-xL-mediated apoptotic resistance to doxorubicin by inducing paraptosis. | 2018 Mar 8 |
9 |
| 12 |
30417787 | Molecular Effects of Treatment of Human Colorectal Cancer Cells with Natural and Classical Chemotherapeutic Drugs: Alterations in the Expression of Apoptosis-related BCL2 Family Members, Including BCL2L12. | 2018 |
1 |
| 13 |
28230534 | Knockdown of antiapoptotic genes in breast cancer cells by siRNA loaded into hybrid nanoparticles. | 2017 Apr 28 |
1 |
| 14 |
28236188 | Co-delivery of Doxorubicin Encapsulated PLGA Nanoparticles and Bcl-xL shRNA Using Alkyl-Modified PEI into Breast Cancer Cells. | 2017 Sep |
2 |
| 15 |
28711493 | Anti-cancer effect of oncolytic adenovirus-armed shRNA targeting MYCN gene on doxorubicin-resistant neuroblastoma cells. | 2017 Sep 9 |
1 |
| 16 |
28714472 | Targeting the differential addiction to anti-apoptotic BCL-2 family for cancer therapy. | 2017 Jul 17 |
1 |
| 17 |
28732245 | Interleukin-4 receptor-targeted delivery of Bcl-xL siRNA sensitizes tumors to chemotherapy and inhibits tumor growth. | 2017 Oct |
1 |
| 18 |
26694174 | Bim directly antagonizes Bcl-xl in doxorubicin-induced prostate cancer cell apoptosis independently of p53. | 2016 |
5 |
| 19 |
26892009 | Sec6/8 regulates Bcl-2 and Mcl-1, but not Bcl-xl, in malignant peripheral nerve sheath tumor cells. | 2016 May |
2 |
| 20 |
27222034 | MicroRNA-184 Modulates Doxorubicin Resistance in Osteosarcoma Cells by Targeting BCL2L1. | 2016 May 25 |
3 |
| 21 |
27841296 | Didox and resveratrol sensitize colorectal cancer cells to doxorubicin via activating apoptosis and ameliorating P-glycoprotein activity. | 2016 Nov 14 |
1 |
| 22 |
25243873 | Effect of citral on the cytotoxicity of doxorubicin in human B-lymphoma cells. | 2015 Feb |
1 |
| 23 |
25789066 | A let-7b binding site SNP in the 3'-UTR of the Bcl-xL gene enhances resistance to 5-fluorouracil and doxorubicin in breast cancer cells. | 2015 Apr |
5 |
| 24 |
25818183 | Sensitizing osteosarcoma stem cells to doxorubicin-induced apoptosis through retention of doxorubicin and modulation of apoptotic-related proteins. | 2015 Jun 1 |
1 |
| 25 |
26320837 | Bisphenol A at the reference level counteracts doxorubicin transcriptional effects on cancer related genes in HT29 cells. | 2015 Dec |
1 |
| 26 |
26416351 | Pharmacological inhibition of Bcl-xL sensitizes osteosarcoma to doxorubicin. | 2015 Nov 3 |
4 |
| 27 |
26473375 | JNJ-26481585 primes rhabdomyosarcoma cells for chemotherapeutics by engaging the mitochondrial pathway of apoptosis. | 2015 Nov 10 |
1 |
| 28 |
26504757 | Doxorubicin Changes Bax /Bcl-xL Ratio, Caspase-8 and 9 in Breast Cancer Cells. | 2015 Sep |
7 |
| 29 |
24626197 | Opioid receptor activation triggering downregulation of cAMP improves effectiveness of anti-cancer drugs in treatment of glioblastoma. | 2014 |
1 |
| 30 |
24814395 | Chemosensitization of rhabdomyosarcoma cells by the histone deacetylase inhibitor SAHA. | 2014 Aug 28 |
1 |
| 31 |
23232767 | Overexpression of Yes-associated protein confers doxorubicin resistance in hepatocellullar carcinoma. | 2013 Feb |
1 |
| 32 |
23292448 | NF1 deficiency causes Bcl-xL upregulation in Schwann cells derived from neurofibromatosis type 1-associated malignant peripheral nerve sheath tumors. | 2013 Feb |
2 |
| 33 |
23613425 | A biodegradable polymersome containing Bcl-xL siRNA and doxorubicin as a dual delivery vehicle for a synergistic anticancer effect. | 2013 Jun |
1 |
| 34 |
23965755 | Loss of PDCD4 contributes to enhanced chemoresistance in Glioblastoma multiforme through de-repression of Bcl-xL translation. | 2013 Sep |
1 |
| 35 |
22664653 | Inhibition of Bcl-xL by ABT-737 enhances chemotherapy sensitivity in neurofibromatosis type 1-associated malignant peripheral nerve sheath tumor cells. | 2012 Aug |
2 |
| 36 |
21357440 | Mechanisms of drug sensitization to TRA-8, an agonistic death receptor 5 antibody, involve modulation of the intrinsic apoptotic pathway in human breast cancer cells. | 2011 Apr |
1 |
| 37 |
21763329 | Activity of selenium on cell proliferation, cytotoxicity, and apoptosis and on the expression of CASP9, BCL-XL and APC in intestinal adenocarcinoma cells. | 2011 Oct 1 |
1 |
| 38 |
20206622 | Non-receptor tyrosine kinase Etk is involved in the apoptosis of small cell lung cancer cells. | 2010 Jun |
2 |
| 39 |
20400521 | The proapoptotic molecule BLID interacts with Bcl-XL and its downregulation in breast cancer correlates with poor disease-free and overall survival. | 2010 Jun 1 |
1 |
| 40 |
20811701 | Functional cell surface expression of toll-like receptor 9 promotes cell proliferation and survival in human hepatocellular carcinomas. | 2010 Oct |
1 |
| 41 |
20820630 | Multiplexed, high-throughput analysis of 3D microtissue suspensions. | 2010 Oct |
1 |
| 42 |
20884855 | Sildenafil increases chemotherapeutic efficacy of doxorubicin in prostate cancer and ameliorates cardiac dysfunction. | 2010 Oct 19 |
2 |
| 43 |
19082486 | Grade-dependent effects on cell cycle progression and apoptosis in response to doxorubicin in human bladder cancer cell lines. | 2009 Jan |
1 |
| 44 |
19502069 | Interaction of doxorubicin with the subcellular structures of the sensitive and Bcl-xL-overexpressing MCF-7 cell line: confocal and low-energy-loss transmission electron microscopy. | 2009 Oct |
8 |
| 45 |
19726787 | Live-cell imaging of caspase activation for high-content screening. | 2009 Sep |
1 |
| 46 |
17912235 | RNA aptamer-targeted inhibition of NF-kappa B suppresses non-small cell lung cancer resistance to doxorubicin. | 2008 Jan |
1 |
| 47 |
18560228 | Effect of doxorubicin on telomerase activity and apoptotic gene expression in doxorubicin-resistant and -sensitive MCF-7 cells: an experimental study. | 2008 |
1 |
| 48 |
17922852 | Low concentrations of doxorubicin sensitizes human solid cancer cells to tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-receptor (R) 2-mediated apoptosis by inducing TRAIL-R2 expression. | 2007 Dec |
1 |
| 49 |
17923112 | Bcl-xL blocks high dose doxorubicin-induced apoptosis but not low dose doxorubicin-induced cell death through mitotic catastrophe. | 2007 Nov 30 |
4 |
| 50 |
16483679 | A combined treatment TNF-alpha/doxorubicin alleviates the resistance of MCF-7/Adr cells to cytotoxic treatment. | 2006 Feb |
1 |