Proline

peptidylprolyl cis/trans isomerase, NIMA-interacting 1 ; Homo sapiens







172 Article(s)
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101 22848287 The prolyl isomerase Pin1 is overexpressed in human esophageal cancer. 2011 Nov 2
102 19920136 Pin1 promotes transforming growth factor-beta-induced migration and invasion. 2010 Jan 15 1
103 19996102 Proline cis/trans-isomerase Pin1 regulates peroxisome proliferator-activated receptor gamma activity through the direct binding to the activation function-1 domain. 2010 Jan 29 1
104 20009523 Pin1 expression contributes to lung cancer: Prognosis and carcinogenesis. 2010 Jan 1
105 20110589 Phosphorylation-specific peptidyl-prolyl isomerization of neuronal cytoskeletal proteins by Pin1: implications for therapeutics in neurodegeneration. 2010 1
106 20179103 Active Mek2 as a regulatory scaffold that promotes Pin1 binding to BPGAP1 to suppress BPGAP1-induced acute Erk activation and cell migration. 2010 Mar 15 2
107 20179161 The prolyl isomerase Pin1 enhances HER-2 expression and cellular transformation via its interaction with mitogen-activated protein kinase/extracellular signal-regulated kinase kinase 1. 2010 Mar 1
108 20207139 Structure-based design of novel human Pin1 inhibitors (II). 2010 Apr 1 1
109 20214639 Interaction and structural modification of topoisomerase IIalpha by peptidyl prolyl isomerase, pin1: an in silico study. 2010 Feb 1
110 20529865 Uncoating of human immunodeficiency virus type 1 requires prolyl isomerase Pin1. 2010 Aug 13 2
111 20682773 Prolyl isomerase Pin1 regulates transcription factor LSF (TFCP2) by facilitating dephosphorylation at two serine-proline motifs. 2010 Oct 8 1
112 20932746 Discovery of cell-active phenyl-imidazole Pin1 inhibitors by structure-guided fragment evolution. 2010 Nov 15 2
113 19168580 The prolyl isomerase Pin1 interacts with a ribosomal protein S6 kinase to enhance insulin-induced AP-1 activity and cellular transformation. 2009 Apr 1
114 19288014 Pin1 overexpression is associated with poor differentiation and survival in oral squamous cell carcinoma. 2009 Apr 1
115 19291099 Discovery and binding studies on a series of novel Pin1 ligands. 2009 Apr 1
116 19439498 Cytosolic Aryl sulfotransferase 4A1 interacts with the peptidyl prolyl cis-trans isomerase Pin1. 2009 Aug 1
117 19592546 Expression of Pin1 mRNA in non-small-cell lung cancer patients. 2009 Apr 1
118 19597489 Prolyl isomerase Pin1 acts as a switch to control the degree of substrate ubiquitylation. 2009 Aug 1
119 19890497 Pin1 as an anticancer drug target. 2009 Sep 1
120 19940183 Peptidyl-prolyl isomerase 1 regulates protein phosphatase 2A-mediated topographic phosphorylation of neurofilament proteins. 2009 Nov 25 1
121 18062707 Binding of phosphatase inhibitor-2 to prolyl isomerase Pin1 modifies specificity for mitotic phosphoproteins. 2008 Jan 8 1
122 18357725 [Recent advances in the study of pin1 and its inhibitors]. 2008 Jan 1
123 18359295 Pin1 interacts with c-Myb in a phosphorylation-dependent manner and regulates its transactivation activity. 2008 Jun 1
124 18473735 Phosphorylation-specific prolyl isomerase Pin1 as a new diagnostic and therapeutic target for cancer. 2008 May 1
125 17241154 Novel modulators of amyloid-beta precursor protein processing. 2007 Jan 1
126 17355867 Substrate recognition reduces side-chain flexibility for conserved hydrophobic residues in human Pin1. 2007 Mar 1
127 17383430 Pin1 interacts with a specific serine-proline motif of hepatitis B virus X-protein to enhance hepatocarcinogenesis. 2007 Mar 3
128 17626162 Inhibition of Pin1 reduces glutamate-induced perikaryal accumulation of phosphorylated neurofilament-H in neurons. 2007 Sep 4
129 17906639 The prolyl isomerase Pin1 orchestrates p53 acetylation and dissociation from the apoptosis inhibitor iASPP. 2007 Oct 1
130 16652378 Targeting carcinogenesis: a role for the prolyl isomerase Pin1? 2006 Jun 1
131 16706410 Theoretical and experimental investigation of the energetics of cis-trans proline isomerization in peptide models. 2006 May 25 2
132 16818231 Ubiquitylation of cyclin E requires the sequential function of SCF complexes containing distinct hCdc4 isoforms. 2006 Jul 7 2
133 16841372 PIN1 expression contributes to hepatic carcinogenesis. 2006 Sep 1
134 16847925 High Pin1 expression is associated with tumor progression in colorectal cancer. 2006 Aug 1 1
135 16865248 Pin1 contributes to cervical tumorigenesis by regulating cyclin D1 expression. 2006 Sep 1
136 16945100 Pin1 in Alzheimer's disease. 2006 Sep 1
137 17002312 Thermodynamics of phosphopeptide binding to the human peptidyl prolyl cis/trans isomerase Pin1. 2006 Oct 3 1
138 21176462 [Expression and its significance of Pin1 and β-catenin in squamous cell carcinoma and adenocarcinoma of the lung]. 2006 Oct 20 1
139 15615648 Pinning down phosphorylated tau and tauopathies. 2005 Jan 3 1
140 15701524 The multifunctional nuclear protein p54nrb is multiphosphorylated in mitosis and interacts with the mitotic regulator Pin1. 2005 Mar 4 1
141 15867923 Phosphorylation-specific prolyl isomerization: is there an underlying theme? 2005 May 2
142 15893113 p53 Protein is activated by Pin1: and also by Cu-SOD prion-like enzyme. 2005 1
143 15964795 Mutations in proline 82 of p53 impair its activation by Pin1 and Chk2 in response to DNA damage. 2005 Jul 2
144 16123044 Regulation of the transcriptional activity of c-Fos by ERK. A novel role for the prolyl isomerase PIN1. 2005 Oct 21 1
145 14681225 Extracellular signal-regulated kinases 1/2 are serum-stimulated "Bim(EL) kinases" that bind to the BH3-only protein Bim(EL) causing its phosphorylation and turnover. 2004 Mar 5 1
146 15082314 Pinning down cell signaling, cancer and Alzheimer's disease. 2004 Apr 1
147 15111319 Prevalent overexpression of prolyl isomerase Pin1 in human cancers. 2004 May 1
148 15171797 Multisite phosphorylation of Pin1-associated mitotic phosphoproteins revealed by monoclonal antibodies MPM-2 and CC-3. 2004 Jun 1 1
149 15474361 Shortfalls in the peptidyl-prolyl cis-trans isomerase protein Pin1 in neurons are associated with frontotemporal dementias. 2004 Nov 1
150 12571275 Prolyl isomerase Pin1: a catalyst for oncogenesis and a potential therapeutic target in cancer. 2003 Mar 1 1