| 51 |
25831499 | Phosphorylation of ORF1p is required for L1 retrotransposition. | 2015 Apr 7 |
1 |
| 52 |
25849135 | Active Pin1 is a key target of all-trans retinoic acid in acute promyelocytic leukemia and breast cancer. | 2015 May |
2 |
| 53 |
26133706 | Peptidyl-Prolyl cis/trans Isomerase NIMA-Interacting 1 as a Therapeutic Target in Hepatocellular Carcinoma. | 2015 |
2 |
| 54 |
26236013 | Pin1-Induced Proline Isomerization in Cytosolic p53 Mediates BAX Activation and Apoptosis. | 2015 Aug 20 |
1 |
| 55 |
26332362 | Chemical Tools To Decipher Regulation of Phosphatases by Proline Isomerization on Eukaryotic RNA Polymerase II. | 2015 Oct 16 |
1 |
| 56 |
26406962 | Modulating the Affinities of Phosphopeptides for the Human Pin1 WW Domain Using 4-Substituted Proline Derivatives. | 2015 Oct 13 |
1 |
| 57 |
26508545 | Peptidyl prolyl isomerase Pin1-inhibitory activity of D-glutamic and D-aspartic acid derivatives bearing a cyclic aliphatic amine moiety. | 2015 Dec 1 |
2 |
| 58 |
26655473 | Pre-Anchoring of Pin1 to Unphosphorylated c-Myc in a Fuzzy Complex Regulates c-Myc Activity. | 2015 Dec 1 |
1 |
| 59 |
23839950 | Modulating the folding stability and ligand binding affinity of Pin1 WW domain by proline ring puckering. | 2014 Jan |
1 |
| 60 |
24267382 | Structure of human Sp140 PHD finger: an atypical fold interacting with Pin1. | 2014 Jan |
1 |
| 61 |
24534472 | Regulation of protein conformation by Pin1 offers novel disease mechanisms and therapeutic approaches in Alzheimer's disease. | 2014 Feb |
2 |
| 62 |
24840168 | Cysteine-mediated dynamic hydrogen-bonding network in the active site of Pin1. | 2014 Jun 17 |
1 |
| 63 |
24982848 | ShaPINg Cell Fate Upon DNA Damage: Role of Pin1 Isomerase in DNA Damage-Induced Cell Death and Repair. | 2014 |
1 |
| 64 |
25059768 | The influence of Ser-154, Cys-113, and the phosphorylated threonine residue on the catalytic reaction mechanism of Pin1. | 2014 Aug 21 |
2 |
| 65 |
25091930 | Structure-based design of novel human Pin1 inhibitors (III): optimizing affinity beyond the phosphate recognition pocket. | 2014 Sep 1 |
1 |
| 66 |
25100325 | The C113D mutation in human Pin1 causes allosteric structural changes in the phosphate binding pocket of the PPIase domain through the tug of war in the dual-histidine motif. | 2014 Sep 2 |
1 |
| 67 |
25120724 | PIN1 promoter polymorphism (-842 G>C) contributes to a decreased risk of cancer: Evidence from meta-analysis. | 2014 Sep |
1 |
| 68 |
25124924 | Prolyl isomerase Pin1 in cancer. | 2014 Sep |
1 |
| 69 |
25197063 | C-terminal domain small phosphatase 1 and MAP kinase reciprocally control REST stability and neuronal differentiation. | 2014 Sep 16 |
1 |
| 70 |
25485500 | p63 threonine phosphorylation signals the interaction with the WW domain of the E3 ligase Itch. | 2014 |
1 |
| 71 |
22549912 | The prolyl isomerase Pin1 interacts with and downregulates the activity of AMPK leading to induction of tumorigenicity of hepatocarcinoma cells. | 2013 Oct |
1 |
| 72 |
22580604 | Prolyl isomerase Pin1 downregulates tumor suppressor RUNX3 in breast cancer. | 2013 Mar 21 |
1 |
| 73 |
23157676 | Distinct functions of cis and trans phosphorylated tau in Alzheimer's disease and their therapeutic implications. | 2013 Aug |
1 |
| 74 |
23221557 | Pin1 interacts with the Epstein-Barr virus DNA polymerase catalytic subunit and regulates viral DNA replication. | 2013 Feb |
2 |
| 75 |
23280577 | Pin1 and nuclear receptors: a new language? | 2013 Sep |
1 |
| 76 |
23333752 | PIN1 inhibits apoptosis in hepatocellular carcinoma through modulation of the antiapoptotic function of survivin. | 2013 Mar |
1 |
| 77 |
23362255 | Isomerase Pin1 stimulates dephosphorylation of tau protein at cyclin-dependent kinase (Cdk5)-dependent Alzheimer phosphorylation sites. | 2013 Mar 15 |
1 |
| 78 |
23407864 | Non-catalytic participation of the Pin1 peptidyl-prolyl isomerase domain in target binding. | 2013 |
1 |
| 79 |
23708493 | Pin1-Nanog expression in human glioma is correlated with advanced tumor progression. | 2013 Aug |
1 |
| 80 |
23887939 | Pin1 promotes GR transactivation by enhancing recruitment to target genes. | 2013 Oct |
2 |
| 81 |
23994618 | Destabilization of KLF10, a tumor suppressor, relies on thr93 phosphorylation and isomerase association. | 2013 Dec |
2 |
| 82 |
21660049 | A critical step for JNK activation: isomerization by the prolyl isomerase Pin1. | 2012 Jan |
1 |
| 83 |
22002310 | Prolyl isomerase Pin1 stabilizes and activates orphan nuclear receptor TR3 to promote mitogenesis. | 2012 Jun 7 |
2 |
| 84 |
22235112 | γ-Aminobutyric acid type A (GABAA) receptor activation modulates tau phosphorylation. | 2012 Feb 24 |
3 |
| 85 |
22318721 | Peptidyl-prolyl isomerase Pin1 controls down-regulation of conventional protein kinase C isozymes. | 2012 Apr 13 |
1 |
| 86 |
22670809 | Structural and kinetic analysis of prolyl-isomerization/phosphorylation cross-talk in the CTD code. | 2012 Aug 17 |
2 |
| 87 |
22789442 | Dual function of Pin1 in NR4A nuclear receptor activation: enhanced activity of NR4As and increased Nur77 protein stability. | 2012 Oct |
2 |
| 88 |
22900083 | Solution structural analysis of the single-domain parvulin TbPin1. | 2012 |
1 |
| 89 |
22976962 | Electrochemical investigations of Tau protein phosphorylations and interactions with Pin1. | 2012 Sep |
1 |
| 90 |
23025283 | Complete thermodynamic and kinetic characterization of the isomer-specific interaction between Pin1-WW domain and the amyloid precursor protein cytoplasmic tail phosphorylated at Thr668. | 2012 Oct 30 |
2 |
| 91 |
23030417 | How does Pin1 catalyze the cis-trans prolyl peptide bond isomerization? A QM/MM and mean reaction force study. | 2012 Nov 1 |
1 |
| 92 |
21219594 | Increased expression of PIN1 gene in papillary thyroid carcinoma. | 2011 Jan 10 |
4 |
| 93 |
21682951 | Peptidyl-prolyl cis-trans isomerase Pin1 in ageing, cancer and Alzheimer disease. | 2011 Jun 20 |
1 |
| 94 |
21714498 | Molecular basis for an ancient partnership between prolyl isomerase Pin1 and phosphatase inhibitor-2. | 2011 Aug 2 |
1 |
| 95 |
21746900 | Stereospecific gating of functional motions in Pin1. | 2011 Jul 26 |
1 |
| 96 |
21764651 | Tumor suppressive activity of prolyl isomerase Pin1 in renal cell carcinoma. | 2011 Oct |
2 |
| 97 |
21852138 | Prolyl isomerase Pin1 as a molecular switch to determine the fate of phosphoproteins. | 2011 Oct |
1 |
| 98 |
21947912 | Complete determination of the Pin1 catalytic domain thermodynamic cycle by NMR lineshape analysis. | 2011 Sep |
2 |
| 99 |
21967280 | Conformational selection in the recognition of phosphorylated substrates by the catalytic domain of human Pin1. | 2011 Nov 8 |
1 |
| 100 |
21980916 | A reduced-amide inhibitor of Pin1 binds in a conformation resembling a twisted-amide transition state. | 2011 Nov 8 |
1 |