Phosphatidylinositol 4,5-Diphosphate

phospholipase C delta 1 ; Homo sapiens







28 Article(s)
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1 34048227 The Pleckstrin Homology Domain of PLCδ1 Exhibits Complex Dissociation Properties at the Inner Leaflet of Plasma Membrane Sheets. 2021 Jun 16 3
2 27042944 Improved Side Chain Dynamics in MARTINI Simulations of Protein-Lipid Interfaces. 2016 May 10 2
3 26040325 A strategy for analyzing bond strength and interaction kinetics between Pleckstrin homology domains and PI(4,5)P2 phospholipids using force distance spectroscopy and surface plasmon resonance. 2015 Jul 7 1
4 26365802 Molecular Basis for Cooperative Binding of Anionic Phospholipids to the PH Domain of the Arf GAP ASAP1. 2015 Nov 3 1
5 22496355 Arsenic trioxide induces abnormal mitotic spindles through a PIP4KIIγ/Rho pathway. 2012 Jul 1
6 21514270 Phosphatidylinositol 5-phosphate 4-kinase type II beta is required for vitamin D receptor-dependent E-cadherin expression in SW480 cells. 2011 May 20 1
7 17908156 Visualization of phosphatidylinositol 4,5-bisphosphate in the plasma membrane of suspension-cultured tobacco BY-2 cells and whole Arabidopsis seedlings. 2007 Dec 1
8 15755258 Membrane activity of the phospholipase C-delta1 pleckstrin homology (PH) domain. 2005 Jul 15 5
9 15778699 Effects of synaptotagmin reveal two distinct mechanisms of agonist-stimulated internalization of the M4 muscarinic acetylcholine receptor. 2005 Mar 1
10 16000311 Role of phospholipase C-zeta domains in Ca2+-dependent phosphatidylinositol 4,5-bisphosphate hydrolysis and cytoplasmic Ca2+ oscillations. 2005 Sep 2 1
11 16246104 The regulation of membrane to cytosol partitioning of signalling proteins by phosphoinositides and their soluble headgroups. 2005 Dec 1
12 14670369 Real-time analysis of phospholipase C activity during different patterns of receptor-induced Ca2+ responses in HEK293 cells. 2004 Jan 1
13 15447683 Rho-mediated cytoskeletal rearrangement in response to LPA is functionally antagonized by Rac1 and PIP2. 2004 Oct 2
14 15456883 Phosphatidylinositol-4,5-bisphosphate-rich plasma membrane patches organize active zones of endocytosis and ruffling in cultured adipocytes. 2004 Oct 1
15 11964166 Subcellular localization of phosphatidylinositol 4,5-bisphosphate using the pleckstrin homology domain of phospholipase C delta1. 2002 May 1 1
16 11325731 Microelectrophoresis of a bilayer-coated silica bead in an optical trap: application to enzymology. 2001 May 2
17 10364218 Morphological changes and detachment of adherent cells induced by p122, a GTPase-activating protein for Rho. 1999 Jun 18 2
18 10419523 Activation of phospholipase C delta1 through C2 domain by a Ca(2+)-enzyme-phosphatidylserine ternary complex. 1999 Jul 30 1
19 10491207 Involvement of EF hand motifs in the Ca(2+)-dependent binding of the pleckstrin homology domain to phosphoinositides. 1999 Oct 1 5
20 9417098 Replacements of single basic amino acids in the pleckstrin homology domain of phospholipase C-delta1 alter the ligand binding, phospholipase activity, and interaction with the plasma membrane. 1998 Jan 2 4
21 9512420 Receptor-induced transient reduction in plasma membrane PtdIns(4,5)P2 concentration monitored in living cells. 1998 Mar 12 2
22 9588182 Mutation in the pleckstrin homology domain of the human phospholipase C-delta 1 gene is associated with loss of function. 1998 Apr 28 3
23 9168154 Regulation of phospholipase C delta1 by sphingosine. 1997 Apr 26 1
24 8798711 Positive charge at position 549 is essential for phosphatidylinositol 4,5-bisphosphate-hydrolyzing but not phosphatidylinositol-hydrolyzing activities of human phospholipase C delta1. 1996 Oct 4 2
25 8810295 Phosphatidylinositol 4,5-bisphosphate binding to the pleckstrin homology domain of phospholipase C-delta1 enhances enzyme activity. 1996 Oct 11 4
26 8942652 Inhibition of phospholipase C-delta 1 catalytic activity by sphingomyelin. 1996 Nov 26 1
27 7890667 Cloning and identification of amino acid residues of human phospholipase C delta 1 essential for catalysis. 1995 Mar 10 4
28 8387776 Binding of phospholipase C delta 1 to phospholipid vesicles. 1993 May 1 8