Cocaine

solute carrier family 6 member 3 ; Rattus norvegicus







130 Article(s)
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51 18597947 Short-acting cocaine and long-acting GBR-12909 both elicit rapid dopamine uptake inhibition following intravenous delivery. 2008 Jul 31 1
52 18606182 Different effects of selective dopamine uptake inhibitors, GBR 12909 and WIN 35428, on HIV-1 Tat toxicity in rat fetal midbrain neurons. 2008 Nov 1
53 18634806 Differential cocaine-induced modulation of glutamate and dopamine transporters after contingent and non-contingent administration. 2008 Oct 1
54 17161392 Changes in levels of D1, D2, or NMDA receptors during withdrawal from brief or extended daily access to IV cocaine. 2007 Feb 2 1
55 17169488 Effects of cocaine on monoamine uptake as measured ex vivo. 2007 Feb 21 2
56 17408612 Differential effects of Zn2+ on the kinetics and cocaine inhibition of dopamine transport by the human and rat dopamine transporters. 2007 Jun 22 5
57 17540345 Irreversible binding of a novel phenylisothiocyanate tropane analog to monoamine transporters in rat brain. 2007 Jul 15 2
58 17561841 Nigrostriatal cell firing action on the dopamine transporter. 2007 May 1
59 17980487 Dopamine uptake inhibition is positively correlated with cocaine-induced stereotyped behavior. 2007 Dec 11 1
60 15957006 A reduced rate of in vivo dopamine transporter binding is associated with lower relative reinforcing efficacy of stimulants. 2006 Feb 2
61 16480713 Sigma2 (sigma2) receptors as a target for cocaine action in the rat striatum. 2006 Mar 27 2
62 16586462 Investigation of the potential pharmacokinetic and pharmaco-dynamic drug interaction between AHN 1-055, a potent benztropine analog used for cocaine abuse, and cocaine after dosing in rats using intracerebral microdialysis. 2006 Jul 2
63 16956595 The role of peripheral and central sodium channels in mediating brain temperature fluctuations induced by intravenous cocaine. 2006 Oct 30 1
64 15681658 Effects of 4'-chloro-3 alpha-(diphenylmethoxy)-tropane on mesostriatal, mesocortical, and mesolimbic dopamine transmission: comparison with effects of cocaine. 2005 May 7
65 16095575 Cocaine self-administration and locomotor activity are altered in Lewis and F344 inbred rats by RTI 336, a 3-phenyltropane analog that binds to the dopamine transporter. 2005 Sep 7 2
66 16122767 Differences in interactions with the dopamine transporter as revealed by diminishment of Na(+) gradient and membrane potential: dopamine versus other substrates. 2005 Nov 3
67 16179556 Cocaine induces a differential dose-dependent alteration in the expression profile of immediate early genes, transcription factors, and caspases in PC12 cells: a possible mechanism of neurotoxic damage in cocaine addiction. 2005 Aug 1
68 16212991 Rapid delivery of the dopamine transporter to the plasmalemmal membrane upon amphetamine stimulation. 2005 Nov 1
69 14698755 Prenatal cocaine exposure alters potassium-evoked dopamine release dynamics in rat striatum. 2004 1
70 14711303 Synthesis, monoamine transporter binding properties, and behavioral pharmacology of a series of 3beta-(substituted phenyl)-2beta-(3'-substituted isoxazol-5-yl)tropanes. 2004 Jan 15 2
71 15103693 Covalent and noncovalent chemical modifications of arginine residues decrease dopamine transporter activity. 2004 Jun 15 3
72 15189035 Structure-activity relationships at monoamine transporters for a series of N-substituted 3alpha-(bis[4-fluorophenyl]methoxy)tropanes: comparative molecular field analysis, synthesis, and pharmacological evaluation. 2004 Jun 17 1
73 15464127 Rapid regulation of the dopamine transporter: role in stimulant addiction? 2004 2
74 12490570 Withdrawal from repeated cocaine alters dopamine transporter protein turnover in the rat striatum. 2003 Jan 4
75 12624535 Selective decreases in amphetamine self-administration and regulation of dopamine transporter function in diabetic rats. 2003 Feb 4
76 12649367 Individual differences in cocaine-induced locomotor sensitization in low and high cocaine locomotor-responding rats are associated with differential inhibition of dopamine clearance in nucleus accumbens. 2003 Apr 4
77 12682063 The dopamine transporter constitutively internalizes and recycles in a protein kinase C-regulated manner in stably transfected PC12 cell lines. 2003 Jun 13 2
78 12869648 Dissociation of high-affinity cocaine analog binding and dopamine uptake inhibition at the dopamine transporter. 2003 Aug 4
79 12902997 Individual differences in cocaine-induced locomotor activity in rats: behavioral characteristics, cocaine pharmacokinetics, and the dopamine transporter. 2003 Dec 4
80 12975490 Substrate-induced trafficking of the dopamine transporter in heterologously expressing cells and in rat striatal synaptosomal preparations. 2003 Nov 1
81 14592523 Synthesis and biological activity of 2-carbomethoxy-3-catechol-8-azabicyclo[3.2.1]octanes. 2003 Nov 17 6
82 12105102 Neurokinin receptors modulate the neurochemical actions of cocaine. 2002 Jun 2
83 12130707 A single methamphetamine administration rapidly decreases vesicular dopamine uptake. 2002 Aug 1
84 12183681 Acute cocaine differentially alters accumbens and striatal dopamine clearance in low and high cocaine locomotor responders: behavioral and electrochemical recordings in freely moving rats. 2002 Sep 2
85 12213053 Mazindol analogues as potential inhibitors of the cocaine binding site at the dopamine transporter. 2002 Sep 12 1
86 12235253 Reinforcing strength of a novel dopamine transporter ligand: pharmacodynamic and pharmacokinetic mechanisms. 2002 Oct 3
87 12394414 Effect of cocaine and sucrose withdrawal period on extinction behavior, cue-induced reinstatement, and protein levels of the dopamine transporter and tyrosine hydroxylase in limbic and cortical areas in rats. 2002 Sep 3
88 11150317 Characterization of extracellular dopamine clearance in the medial prefrontal cortex: role of monoamine uptake and monoamine oxidase inhibition. 2001 Jan 1 2
89 11180505 Synthesis and preliminary characterization of a high-affinity novel radioligand for the dopamine transporter. 2001 Feb 1
90 11181904 Regulation of the vesicular monoamine transporter-2: a novel mechanism for cocaine and other psychostimulants. 2001 Mar 2
91 11408534 Dopamine D1 and D2 receptors influence dopamine transporter synthesis and degradation in the rat. 2001 Jul 1
92 11504813 Cocaine-induced increases in vesicular dopamine uptake: role of dopamine receptors. 2001 Sep 1
93 11543766 Peptide derived from insulin with regulatory activity of dopamine transporter. 2001 Sep 2
94 11605081 Role of the dopamine transporter and the sodium channel in the cocaine-like discriminative stimulus effects of local anesthetics in rats. 2001 Sep 3
95 11797070 Cocaine-like discriminative stimulus effects of novel cocaine and 3-phenyltropane analogs in the rat. 2001 Dec 2
96 10614659 Dopamine transporters participate in the physiological regulation of prolactin. 2000 Jan 1
97 10865062 Cocaine inhibits NGF-induced PC12 cells differentiation through D(1)-type dopamine receptors. 2000 Jun 30 1
98 11020233 Novel in vivo electrophysiological assay for the effects of cocaine and putative "cocaine antagonists" on dopamine transporter activity of substantia nigra and ventral tegmental area dopamine neurons. 2000 Dec 1 6
99 11125013 Kappa-opioid receptor activation modifies dopamine uptake in the nucleus accumbens and opposes the effects of cocaine. 2000 Dec 15 1
100 10027875 Age-related reductions in [3H]WIN 35,428 binding to the dopamine transporter in nigrostriatal and mesolimbic brain regions of the fischer 344 rat. 1999 Mar 2