Tacrolimus

FKBP prolyl isomerase 4 ; Homo sapiens







50 Article(s)
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1 34830130 Hypothalamic Regulation of Corticotropin-Releasing Factor under Stress and Stress Resilience. 2021 Nov 12 1
2 32580389 Natural Mating Differentially Triggers Expression of Glucocorticoid Receptor (NR3C1)-Related Genes in the Preovulatory Porcine Female Reproductive Tract. 2020 Jun 22 1
3 32664235 Tacrolimus Prevents TWEAK-Induced PLA2R Expression in Cultured Human Podocytes. 2020 Jul 10 2
4 31661769 Functional Comparison of Human and Zebra Fish FKBP52 Confirms the Importance of the Proline-Rich Loop for Regulation of Steroid Hormone Receptor Activity. 2019 Oct 28 1
5 29023988 Molecular dynamics simulation, binding free energy calculation and unbinding pathway analysis on selectivity difference between FKBP51 and FKBP52: Insight into the molecular mechanism of isoform selectivity. 2018 Jan 1
6 26903089 Isomerization and Oligomerization of Truncated and Mutated Tau Forms by FKBP52 are Independent Processes. 2016 Mar 27 3
7 25888602 The FK506-binding protein FKBP52 in vitro induces aggregation of truncated Tau forms with prion-like behavior. 2015 Aug 2
8 25953903 Coupling of Conformational Transitions in the N-terminal Domain of the 51-kDa FK506-binding Protein (FKBP51) Near Its Site of Interaction with the Steroid Receptor Proteins. 2015 Jun 19 2
9 26858893 Synergistic Effects of Calcineurin Inhibitors and Steroids on Steroid Sensitivity of Peripheral Blood Mononuclear Cells. 2015 Feb 8 1
10 24623856 Immunophilin FKBP52 induces Tau-P301L filamentous assembly in vitro and modulates its activity in a model of tauopathy. 2014 Mar 25 1
11 24749623 Differential conformational dynamics in the closely homologous FK506-binding domains of FKBP51 and FKBP52. 2014 Jul 1 1
12 24899909 In Silico Insight into Potent of Anthocyanin Regulation of FKBP52 to Prevent Alzheimer's Disease. 2014 1
13 23228564 FKBP52 is involved in the regulation of SOCE channels in the human platelets and MEG 01 cells. 2013 Mar 3
14 23933011 Crystal structures of the free and ligand-bound FK1-FK2 domain segment of FKBP52 reveal a flexible inter-domain hinge. 2013 Nov 15 3
15 22455398 Exploration of pipecolate sulfonamides as binders of the FK506-binding proteins 51 and 52. 2012 May 10 1
16 21799260 FKBP immunophilins and Alzheimer's disease: a chaperoned affair. 2011 Aug 1
17 20084280 Control of Alzheimer's amyloid beta toxicity by the high molecular weight immunophilin FKBP52 and copper homeostasis in Drosophila. 2010 Jan 13 1
18 20133804 A role for FKBP52 in Tau protein function. 2010 Feb 9 1
19 19201607 Improvement of monolithic solid material by utilization of spacer for identification of the target using affinity resins. 2009 Mar 1 1
20 16352746 The immunophilin FKBP52 inhibits the activity of the epithelial Ca2+ channel TRPV5. 2006 May 1
21 16996313 Involvement of some large immunophilins and their ligands in the protection and regeneration of neurons: a hypothetical mode of action. 2006 Oct 2
22 15381148 FKBP52. 2005 Jan 4
23 15713424 FK1706, a novel non-immunosuppressive immunophilin: neurotrophic activity and mechanism of action. 2005 Feb 10 1
24 15133031 A novel role for the immunophilin FKBP52 in copper transport. 2004 Jul 2 1
25 15159550 3D structure of human FK506-binding protein 52: implications for the assembly of the glucocorticoid receptor/Hsp90/immunophilin heterocomplex. 2004 Jun 1 1
26 15199065 Association of immunophilins with mammalian TRPC channels. 2004 Aug 13 1
27 12499534 Structure of the N-terminal domain of human FKBP52. 2003 Jan 3
28 12552015 Adeno-associated virus type 2-mediated gene transfer: role of cellular T-cell protein tyrosine phosphatase in transgene expression in established cell lines in vitro and transgenic mice in vivo. 2003 Feb 1
29 12746298 The FK506-binding immunophilin FKBP51 is transcriptionally regulated by progestin and attenuates progestin responsiveness. 2003 Jun 1
30 12782134 Organization of the human FK506-binding immunophilin FKBP52 protein gene (FKBP4). 2003 Jun 1
31 10051602 Immunophilins, Refsum disease, and lupus nephritis: the peroxisomal enzyme phytanoyl-COA alpha-hydroxylase is a new FKBP-associated protein. 1999 Mar 2 4
32 10336507 Immunophilin FK506-binding protein 52 (not FK506-binding protein 12) mediates the neurotrophic action of FK506. 1999 Jun 2
33 10461545 FK506 and the role of the immunophilin FKBP-52 in nerve regeneration. 1999 Aug 2
34 10601253 Different regions of the immunophilin FKBP52 determine its association with the glucocorticoid receptor, hsp90, and cytoplasmic dynein. 1999 Dec 24 3
35 9658403 Calcium/calmodulin kinase inhibitors and immunosuppressant macrolides rapamycin and FK506 inhibit progestin- and glucocorticosteroid receptor-mediated transcription in human breast cancer T47D cells. 1998 Jul 1
36 9195923 Protein phosphatase 5 is a major component of glucocorticoid receptor.hsp90 complexes with properties of an FK506-binding immunophilin. 1997 Jun 27 1
37 8760046 FK-506 and rapamycin but not cyclosporin inhibit aldosterone-stimulated sodium transport in A6 cells. 1996 Jul 1
38 8955134 FAP48, a new protein that forms specific complexes with both immunophilins FKBP59 and FKBP12. Prevention by the immunosuppressant drugs FK506 and rapamycin. 1996 Dec 20 2
39 7476967 Interaction of the progesterone receptor with binding proteins for FK506 and cyclosporin A. 1995 Jul 2
40 7532989 Stabilization in vitro of the untransformed glucocorticoid receptor complex of S49 lymphocytes by the immunophilin ligand FK506. 1995 Feb 3
41 7544285 1H and 15N assignment of NMR spectrum, secondary structure and global folding of the immunophilin-like domain of the 59-kDa FK506-binding protein. 1995 Aug 1 1
42 8584032 Evidence that the FK506-binding immunophilin heat shock protein 56 is required for trafficking of the glucocorticoid receptor from the cytoplasm to the nucleus. 1995 Nov 3
43 7510997 Effects of immunosuppressants FK506 and rapamycin on the heterooligomeric form of the progesterone receptor. 1994 Jan 2
44 7530727 A soluble binding assay for measuring 3H-FK506 binding to the hsp56 immunophilin. 1994 Nov 5
45 7504525 An active FK506-binding domain of 17,000 daltons is isolated following limited proteolysis of chicken thymus hsp56. 1993 Nov 30 4
46 7681058 Potentiation of glucocorticoid receptor-mediated gene expression by the immunophilin ligands FK506 and rapamycin. 1993 Mar 25 1
47 7689858 P59 (FK506 binding protein 59) interaction with heat shock proteins is highly conserved and may involve proteins other than steroid receptors. 1993 Aug 31 1
48 1279700 Expression and characterization of human FKBP52, an immunophilin that associates with the 90-kDa heat shock protein and is a component of steroid receptor complexes. 1992 Nov 15 2
49 1371107 The Hsp56 component of steroid receptor complexes binds to immobilized FK506 and shows homology to FKBP-12 and FKBP-13. 1992 Feb 15 2
50 1383222 Tissue distribution and cellular localization of hsp56, an FK506-binding protein. Characterization using a highly specific polyclonal antibody. 1992 Oct 25 2