| 1 |
35065163 | Therapeutic role of eicosapentaenoic and arachidonic acid in benzo(a) pyrene-induced toxicity in HUVEC endothelial cells. | 2022 Mar 15 |
1 |
| 2 |
33393179 | Pinocembrin attenuates benzo(a)pyrene-induced CYP1A1 expression through multiple pathways: An in vitro and in vivo study. | 2021 Apr |
1 |
| 3 |
33663268 | Chemopreventive effect of galangin against benzo(a)pyrene-induced stomach tumorigenesis through modulating aryl hydrocarbon receptor in Swiss albino mice. | 2021 Sep |
1 |
| 4 |
33800341 | Assessment of 9-OH- and 7,8-diol-benzo[a]pyrene in Blood as Potent Markers of Cognitive Impairment Related to benzo[a]pyrene Exposure: An Animal Model Study. | 2021 Mar 8 |
2 |
| 5 |
33977171 | Benzo[a]pyrene Cytotoxicity Tolerance in Testicular Sertoli Cells Involves Aryl-hydrocarbon Receptor and Cytochrome P450 1A1 Expression Deficiencies. | 2021 Mar |
1 |
| 6 |
34290363 | Roles for B[a]P and FICZ in subchondral bone metabolism and experimental temporomandibular joint osteoarthritis via the AhR/Cyp1a1 signaling axis. | 2021 Jul 21 |
2 |
| 7 |
34472326 | Exposure to an Environmental Mixture of Polycyclic Aromatic Hydrocarbons Induces Hepatic Cytochrome P450 Enzymes in Mice. | 2021 Sep 20 |
1 |
| 8 |
29931584 | Alteration of benzo(a)pyrene biotransformation by resveratrol in ApcMin/+ mouse model of colon carcinogenesis. | 2019 Apr |
1 |
| 9 |
30982974 | Benzo(a)pyrene facilitates dermatophagoides group 1 (Der f 1)-induced epithelial cytokine release through aryl hydrocarbon receptor in asthma. | 2019 Sep |
1 |
| 10 |
29366871 | Cytochrome P450 1A1 (CYP1A1) protects against nonalcoholic fatty liver disease caused by Western diet containing benzo[a]pyrene in mice. | 2018 Mar |
9 |
| 11 |
30165701 | Cigarette Smoke Toxins-Induced Mitochondrial Dysfunction and Pancreatitis Involves Aryl Hydrocarbon Receptor Mediated Cyp1 Gene Expression: Protective Effects of Resveratrol. | 2018 Dec 1 |
2 |
| 12 |
28007926 | Circadian Regulation of Benzo[a]Pyrene Metabolism and DNA Adduct Formation in Breast Cells and the Mouse Mammary Gland. | 2017 Mar |
4 |
| 13 |
28405246 | Modulation of benzo[a]pyrene-DNA adduct formation by CYP1 inducer and inhibitor. | 2017 |
1 |
| 14 |
25995008 | The impact of p53 on DNA damage and metabolic activation of the environmental carcinogen benzo[a]pyrene: effects in Trp53(+/+), Trp53(+/-) and Trp53(-/-) mice. | 2016 Apr |
2 |
| 15 |
26655880 | Naringenin ameliorates inflammation and cell proliferation in benzo(a)pyrene induced pulmonary carcinogenesis by modulating CYP1A1, NFκB and PCNA expression. | 2016 Jan |
1 |
| 16 |
25230394 | Comparison of the metabolic activation of environmental carcinogens in mouse embryonic stem cells and mouse embryonic fibroblasts. | 2015 Feb |
1 |
| 17 |
25911668 | Pulmonary Inflammation Impacts on CYP1A1-Mediated Respiratory Tract DNA Damage Induced by the Carcinogenic Air Pollutant Benzo[a]pyrene. | 2015 Aug |
13 |
| 18 |
26215100 | Screening a mouse liver gene expression compendium identifies modulators of the aryl hydrocarbon receptor (AhR). | 2015 Oct 2 |
1 |
| 19 |
24394547 | Protective role of cytochrome P450 1A1 (CYP1A1) against benzo[a]pyrene-induced toxicity in mouse aorta. | 2014 Feb 28 |
10 |
| 20 |
24497629 | Mitochondrial targeting of cytochrome P450 (CYP) 1B1 and its role in polycyclic aromatic hydrocarbon-induced mitochondrial dysfunction. | 2014 Apr 4 |
1 |
| 21 |
24530354 | Cytochrome b5 and epoxide hydrolase contribute to benzo[a]pyrene-DNA adduct formation catalyzed by cytochrome P450 1A1 under low NADPH:P450 oxidoreductase conditions. | 2014 Apr 6 |
6 |
| 22 |
25297811 | Benzo pyrene-induced DNA adducts and gene expression profiles in target and non-target organs for carcinogenesis in mice. | 2014 Oct 8 |
1 |
| 23 |
23047765 | Oral benzo[a]pyrene in Cyp1a1/1b1(-/-) double-knockout mice: Microarray analysis during squamous cell carcinoma formation in preputial gland duct. | 2013 May 1 |
1 |
| 24 |
23761301 | Oral benzo[a]pyrene: understanding pharmacokinetics, detoxication, and consequences--Cyp1 knockout mouse lines as a paradigm. | 2013 Sep |
1 |
| 25 |
22442665 | TLR2 controls intestinal carcinogen detoxication by CYP1A1. | 2012 |
2 |
| 26 |
22486318 | Regulation of the activity and expression of aryl hydrocarbon receptor by ethanol in mouse hepatic stellate cells. | 2012 Nov |
2 |
| 27 |
22619112 | Proliferating primary hepatocytes from the pUR288 lacZ plasmid mouse are valuable tools for genotoxicity assessment in vitro. | 2012 Jun |
1 |
| 28 |
21130824 | The antigenotoxic effects of grapefruit juice on the damage induced by benzo(a)pyrene and evaluation of its interaction with hepatic and intestinal Cytochrome P450 (Cyp) 1a1. | 2011 Apr |
1 |
| 29 |
21733121 | Benzo[a]pyrene exposure increases toxic biomarkers and morphological disorders in mouse cervix. | 2011 Nov |
1 |
| 30 |
21872649 | Mechanisms involved in lipid accumulation and apoptosis induced by 1-nitropyrene in Hepa1c1c7 cells. | 2011 Oct 30 |
2 |
| 31 |
20127859 | Oral benzo[a]pyrene-induced cancer: two distinct types in different target organs depend on the mouse Cyp1 genotype. | 2010 Nov 15 |
1 |
| 32 |
20371670 | Organ-specific roles of CYP1A1 during detoxication of dietary benzo[a]pyrene. | 2010 Jul |
5 |
| 33 |
20400470 | The role of small-intestinal P450 enzymes in protection against systemic exposure of orally administered benzo[a]pyrene. | 2010 Jul |
3 |
| 34 |
19666105 | Overexpression of Cu/Zn-superoxide dismutase and/or catalase accelerates benzo(a)pyrene detoxification by upregulation of the aryl hydrocarbon receptor in mouse endothelial cells. | 2009 Oct 15 |
3 |
| 35 |
17997381 | Basal and inducible CYP1 mRNA quantitation and protein localization throughout the mouse gastrointestinal tract. | 2008 Feb 15 |
1 |
| 36 |
18022386 | Inducibility of cytochrome P450 1A1 and chemical carcinogenesis by benzo[a]pyrene in AhR repressor-deficient mice. | 2008 Jan 18 |
1 |
| 37 |
18372398 | Phenotype of the Cyp1a1/1a2/1b1-/- triple-knockout mouse. | 2008 Jun |
8 |
| 38 |
18694800 | The effect of initiating doses of benzo[a]pyrene and 7,12-dimethylbenz[a]anthracene on the expression of PAH activating enzymes and its modulation by plant phenols. | 2008 Sep 29 |
1 |
| 39 |
17433523 | Abundance of aryl hydrocarbon receptor potentiates benzo[a]pyrene-induced apoptosis in Hepa1c1c7 cells via CYP1A1 activation. | 2007 Jun 3 |
1 |
| 40 |
16377763 | Oral benzo[a]pyrene in Cyp1 knockout mouse lines: CYP1A1 important in detoxication, CYP1B1 metabolism required for immune damage independent of total-body burden and clearance rate. | 2006 Apr |
8 |
| 41 |
15667830 | Induction of CYP1A1 and CYP1B1 in liver and lung by benzo(a)pyrene and 7,12-d imethylbenz(a)anthracene do not affect distribution of polycyclic hydrocarbons to target tissue: role of AhR and CYP1B1 in bone marrow cytotoxicity. | 2005 Feb 1 |
3 |
| 42 |
14976333 | Modulation of carcinogen metabolism and DNA interaction by calcium glucarate in mouse skin. | 2004 May |
2 |
| 43 |
15102951 | Oral exposure to benzo[a]pyrene in the mouse: detoxication by inducible cytochrome P450 is more important than metabolic activation. | 2004 May |
1 |
| 44 |
15279838 | Establishment of ten strains of genetically engineered Salmonella typhimurium TA1538 each co-expressing a form of human cytochrome P450 with NADPH-cytochrome P450 reductase sensitive to various promutagens. | 2004 Aug 8 |
1 |
| 45 |
12455047 | Polycyclic aromatic hydrocarbon-inducible DNA adducts: evidence by 32P-postlabeling and use of knockout mice for Ah receptor-independent mechanisms of metabolic activation in vivo. | 2003 Jan 1 |
2 |
| 46 |
12649394 | Role of cytochrome P4501B1 in benzo[a]pyrene bioactivation to DNA-binding metabolites in mouse vascular smooth muscle cells: evidence from 32P-postlabeling for formation of 3-hydroxybenzo[a]pyrene and benzo[a]pyrene-3,6-quinone as major proximate genotoxic intermediates. | 2003 Apr |
3 |
| 47 |
14613719 | Bone marrow cytotoxicity of benzo[a]pyrene is dependent on CYP1B1 but is diminished by Ah receptor-mediated induction of CYP1A1 in liver. | 2003 Nov 15 |
2 |
| 48 |
11171528 | Applications of gene arrays in environmental toxicology: fingerprints of gene regulation associated with cadmium chloride, benzo(a)pyrene, and trichloroethylene. | 2001 Jan |
1 |
| 49 |
11577022 | Constitutive and inducible expression of Cyp1a1 and Cyp1b1 in vascular smooth muscle cells: role of the Ahr bHLH/PAS transcription factor. | 2001 Sep 28 |
1 |
| 50 |
11741297 | Benzo[a]pyrene-induced toxicity: paradoxical protection in Cyp1a1(-/-) knockout mice having increased hepatic BaP-DNA adduct levels. | 2001 Dec 21 |
3 |