| 1 |
30949058 | The Central Role of Glucokinase in Glucose Homeostasis: A Perspective 50 Years After Demonstrating the Presence of the Enzyme in Islets of Langerhans. | 2019 |
1 |
| 2 |
30983961 | When a Little Bit More Makes the Difference: Expression Levels of GKRP Determines the Subcellular Localization of GK in Tanycytes. | 2019 |
2 |
| 3 |
31372018 | Diagnosis and management of glucokinase monogenic diabetes in pregnancy: current perspectives. | 2019 |
1 |
| 4 |
29885360 | Determinants of human glucokinase activation and implications for small molecule allosteric control. | 2018 Sep |
2 |
| 5 |
28655753 | The thermodynamic basis of glucose-stimulated insulin release: a model of the core mechanism. | 2017 Jun |
2 |
| 6 |
26299854 | [Glucokinase and glucokinase regulatory proteins as molecular targets for novel antidiabetic drugs]. | 2015 Jul-Aug |
2 |
| 7 |
24056026 | Treatment with glucokinase activator, YH-GKA, increases cell proliferation and decreases glucotoxic apoptosis in INS-1 cells. | 2014 Jan 23 |
2 |
| 8 |
24447076 | Identification and analysis of novel R308K mutation in glucokinase of type 2 diabetic patient and its kinetic correlation. | 2014 Sep-Oct |
1 |
| 9 |
24696842 | GCK gene-body hypomethylation is associated with the risk of coronary heart disease. | 2014 |
2 |
| 10 |
25052034 | Recent updates on glucokinase activators for the treatment of type 2 diabetes mellitus. | 2014 |
1 |
| 11 |
23476789 | Structural Variations of Human Glucokinase Glu256Lys in MODY2 Condition Using Molecular Dynamics Study. | 2013 |
2 |
| 12 |
23573289 | Evolution of hepatic glucose metabolism: liver-specific glucokinase deficiency explained by parallel loss of the gene for glucokinase regulatory protein (GCKR). | 2013 |
1 |
| 13 |
24226772 | Antidiabetic effects of glucokinase regulatory protein small-molecule disruptors. | 2013 Dec 19 |
2 |
| 14 |
22107947 | Homotropic allosteric regulation in monomeric mammalian glucokinase. | 2012 Mar 15 |
1 |
| 15 |
23149230 | The discovery of a novel series of glucokinase activators based on a pyrazolopyrimidine scaffold. | 2012 Dec 15 |
1 |
| 16 |
21490074 | Hepatic glucokinase expression is associated with lipogenesis and fatty liver in humans. | 2011 Jul |
2 |
| 17 |
22101819 | The active conformation of human glucokinase is not altered by allosteric activators. | 2011 Nov |
2 |
| 18 |
20977462 | Curcumin prevents leptin raising glucose levels in hepatic stellate cells by blocking translocation of glucose transporter-4 and increasing glucokinase. | 2010 Nov |
1 |
| 19 |
19520181 | Recent advances in glucokinase activators for the treatment of type 2 diabetes. | 2009 Aug |
1 |
| 20 |
19747136 | Medicinal chemistry approaches for glucokinase activation to treat type 2 diabetes. | 2009 |
2 |
| 21 |
18651836 | Glucokinase and molecular aspects of liver glycogen metabolism. | 2008 Aug 15 |
3 |
| 22 |
17956314 | Glucokinase activators: molecular tools for studying the physiology of insulin-secreting cells. | 2007 Nov |
1 |
| 23 |
16403021 | The role of glucose 6-phosphate in mediating the effects of glucokinase overexpression on hepatic glucose metabolism. | 2006 Jan |
4 |
| 24 |
16787225 | Small molecule glucokinase activators as glucose lowering agents: a new paradigm for diabetes therapy. | 2006 |
2 |
| 25 |
19669468 | Time-dependent mechanisms in beta-cell glucose sensing. | 2006 Oct |
1 |
| 26 |
15667334 | Glucokinase and glucose homeostasis: proven concepts and new ideas. | 2005 Feb |
2 |
| 27 |
14975750 | Cloning and biochemical characterization of a novel mouse ADP-dependent glucokinase. | 2004 Mar 12 |
1 |
| 28 |
12519761 | Glucose 6-phosphate produced by gluconeogenesis and by glucokinase is equally effective in activating hepatic glycogen synthase. | 2003 Mar 14 |
2 |
| 29 |
12765941 | Glucose 6-phosphate regulates hepatic glycogenolysis through inactivation of phosphorylase. | 2003 Jun |
1 |
| 30 |
12829248 | Control of glycogen deposition. | 2003 Jul 3 |
4 |
| 31 |
11594461 | Reduced enzymatic activity of glucokinase after affinity labeling: results from spectrophotometry and electrospray ionization mass spectrometry. | 2001 May |
1 |
| 32 |
9895293 | Long-term maintenance of low concentrations of fructose for the study of hepatic glucose phosphorylation. | 1999 Feb 1 |
2 |
| 33 |
10455119 | Glucose-6-phosphatase overexpression lowers glucose 6-phosphate and inhibits glycogen synthesis and glycolysis in hepatocytes without affecting glucokinase translocation. Evidence against feedback inhibition of glucokinase. | 1999 Aug 27 |
2 |
| 34 |
9684361 | Purification and characterization of a glucokinase from young tomato (Lycopersicon esculentum L. Mill.) fruit. | 1998 Aug |
1 |
| 35 |
9271087 | Involvement of glucokinase translocation in the mechanism by which resorcinol inhibits glycolysis in hepatocytes. | 1997 Aug 1 |
2 |
| 36 |
8679719 | Kinetics and specificity of human B-cell glucokinase: relevance to hexose-induced insulin release. | 1996 Jun 5 |
1 |
| 37 |
8798601 | Glucose 6-phosphate produced by glucokinase, but not hexokinase I, promotes the activation of hepatic glycogen synthase. | 1996 Sep 27 |
2 |
| 38 |
7614462 | High Km glucose-phosphorylating (glucokinase) activities in a range of tumor cell lines and inhibition of rates of tumor growth by the specific enzyme inhibitor mannoheptulose. | 1995 Aug 1 |
1 |
| 39 |
7869925 | Glucose transport, phosphorylation, and utilization in isolated porcine pancreatic islets. | 1995 Feb |
1 |
| 40 |
7955370 | Fully enzymatic method for determining 1,5-anhydro-D-glucitol in serum. | 1994 Nov |
1 |
| 41 |
7983782 | [Glucokinase gene abnormalities in maturity-onset diabetes of the young (MODY) and late-onset NIDDM]. | 1994 Oct |
2 |
| 42 |
8280078 | Intracellular binding of glucokinase in hepatocytes and translocation by glucose, fructose and insulin. | 1993 Dec 15 |
2 |
| 43 |
8344989 | Interaction of facilitative glucose transporter with glucokinase and its modulation by ADP and glucose-6-phosphate. | 1993 Aug |
1 |
| 44 |
1832811 | Hepatotoxicity caused by dietary secondary products originating from lipid peroxidation. | 1991 |
1 |
| 45 |
2159682 | A formula for quantifying the effects of substrate cycles (futile cycles) on metabolic regulation. Its application to glucose futile cycle in liver as studied by glucose-6-phosphatase/glucokinase determinations. | 1990 Jan-Mar |
2 |
| 46 |
3043440 | Regulation of calcium uptake/efflux from the islet-cell endoplasmic reticulum with regard to the secretion of insulin. | 1988 |
1 |
| 47 |
196677 | [Liberation and reassociation of the microsomal membrane glucokinase in cat liver]. | 1977 |
1 |