Niacinamide

nicotinamide N-methyltransferase ; Homo sapiens







54 Article(s)
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1 35134268 Exploring Unconventional SAM Analogues To Build Cell-Potent Bisubstrate Inhibitors for Nicotinamide N-Methyltransferase. 2022 Apr 11 2
2 35430611 The significance of NAD + metabolites and nicotinamide N-methyltransferase in chronic kidney disease. 2022 Apr 16 4
3 33453420 Nicotinamide N-methyltransferase: At the crossroads between cellular metabolism and epigenetic regulation. 2021 Mar 2
4 33668468 Novel Inhibitors of Nicotinamide-N-Methyltransferase for the Treatment of Metabolic Disorders. 2021 Feb 13 2
5 34029690 Nicotinamide N-methyl transferase (NNMT): An emerging therapeutic target. 2021 Nov 2
6 34377057 Linkage of nanosecond protein motion with enzymatic methyl transfer by nicotinamide N-methyltransferase. 2021 4
7 34424711 Potent Inhibition of Nicotinamide N-Methyltransferase by Alkene-Linked Bisubstrate Mimics Bearing Electron Deficient Aromatics. 2021 Sep 9 5
8 34439880 The Utility of Nicotinamide N-Methyltransferase as a Potential Biomarker to Predict the Oncological Outcomes for Urological Cancers: An Update. 2021 Aug 16 2
9 34458733 Mechanisms and inhibitors of nicotinamide N-methyltransferase. 2021 Aug 18 2
10 34638427 Beyond Nicotinamide Metabolism: Potential Role of Nicotinamide N-Methyltransferase as a Biomarker in Skin Cancers. 2021 Sep 30 2
11 34704059 Macrocyclic peptides as allosteric inhibitors of nicotinamide N-methyltransferase (NNMT). 2021 Oct 7 2
12 32367570 Nicotinamide N-methyltransferase decreases 5-fluorouracil sensitivity in human esophageal squamous cell carcinoma through metabolic reprogramming and promoting the Warburg effect. 2020 Aug 2
13 32622979 Development of fluorescence polarization-based competition assay for nicotinamide N-methyltransferase. 2020 Sep 1 2
14 32651404 Associations of nicotidamide-N-methyltransferase, FTO, and IRX3 genetic variants with body mass index and resting energy expenditure in Mexican subjects. 2020 Jul 10 1
15 30933557 Development of a Suicide Inhibition-Based Protein Labeling Strategy for Nicotinamide N-Methyltransferase. 2019 Apr 19 2
16 31265285 Bisubstrate Inhibitors of Nicotinamide N-Methyltransferase (NNMT) with Enhanced Activity. 2019 Jul 25 3
17 31494172 N1-methylnicotinamide as a possible modulator of cardiovascular risk markers in polycystic ovary syndrome. 2019 Oct 15 1
18 31724854 Novel Propargyl-Linked Bisubstrate Analogues as Tight-Binding Inhibitors for Nicotinamide N-Methyltransferase. 2019 Dec 12 3
19 29420365 Nicotinamide N-methyltransferase: potential involvement in cutaneous malignant melanoma. 2018 Apr 2
20 29549048 The kinetic analysis of the N-methylation of 4-phenylpyridine by nicotinamide N-methyltransferase: Evidence for a novel mechanism of substrate inhibition. 2018 May 1
21 29731364 Covalent inhibitors of nicotinamide N-methyltransferase (NNMT) provide evidence for target engagement challenges in situ. 2018 Sep 1 2
22 29741779 N1-methylnicotinamide (MNAM) as a guardian of cardiovascular system. 2018 Oct 1
23 29805651 Nicotinamide N-methyltransferase enhances the progression of prostate cancer by stabilizing sirtuin 1. 2018 Jun 2
24 29940773 Nicotinamide N-methyltransferase as a potential marker for cancer. 2018 Sep 19 4
25 30044909 Citrullination Inactivates Nicotinamide- N-methyltransferase. 2018 Sep 21 2
26 30093610 NNMT depletion contributes to liver cancer cell survival by enhancing autophagy under nutrient starvation. 2018 Aug 10 2
27 30148963 Kinetic Mechanism of Nicotinamide N-Methyltransferase. 2018 Sep 25 3
28 30226369 Nicotinamide N-Methyltransferase Interacts with Enzymes of the Methionine Cycle and Regulates Methyl Donor Metabolism. 2018 Oct 9 1
29 27810903 NNMT Silencing Activates Tumor Suppressor PP2A, Inactivates Oncogenic STKs, and Inhibits Tumor Forming Ability. 2017 May 1 1
30 28291578 Nicotinamide N-Methyltransferase: More Than a Vitamin B3 Clearance Enzyme. 2017 May 3
31 28548833 Structure-Activity Relationship for Small Molecule Inhibitors of Nicotinamide N-Methyltransferase. 2017 Jun 22 1
32 28726800 Role of Nicotinamide N-Methyltransferase in Dorsal Striatum in Cocaine Place Preference. 2017 Nov 2
33 28758655 Inhibitors of nicotinamide N-methyltransferase designed to mimic the methylation reaction transition state. 2017 Aug 9 2
34 27323852 Nicotinamide N-methyltransferase enhances resistance to 5-fluorouracil in colorectal cancer cells through inhibition of the ASK1-p38 MAPK pathway. 2016 Jul 19 2
35 27389312 Nicotinamide N-methyltransferase catalyses the N-methylation of the endogenous β-carboline norharman: evidence for a novel detoxification pathway. 2016 Oct 1 2
36 27570878 A Rapid and Efficient Assay for the Characterization of Substrates and Inhibitors of Nicotinamide N-Methyltransferase. 2016 Sep 20 5
37 27999813 Physiological Study on Association between Nicotinamide N-Methyltransferase Gene Polymorphisms and Hyperlipidemia. 2016 2
38 26066674 Serum N(1)-Methylnicotinamide Is Associated With Obesity and Diabetes in Chinese. 2015 Aug 1
39 24717514 Nicotinamide N-methyltransferase knockdown protects against diet-induced obesity. 2014 Apr 10 2
40 22536229 Nicotinamide, NAD(P)(H), and Methyl-Group Homeostasis Evolved and Became a Determinant of Ageing Diseases: Hypotheses and Lessons from Pellagra. 2012 2
41 23079201 Primary intrathyroidal paraganglioma: histopathology and novel molecular alterations. 2012 Dec 1
42 21496389 Inhibiting proliferation in KB cancer cells by RNA interference-mediated knockdown of nicotinamide N-methyltransferase expression. 2011 Jan-Mar 2
43 21719135 Cancer stem cell overexpression of nicotinamide N-methyltransferase enhances cellular radiation resistance. 2011 Jun 1
44 21823666 Structural basis of substrate recognition in human nicotinamide N-methyltransferase. 2011 Sep 13 4
45 20495288 Interferon-gamma elevates nicotinamide N-methyltransferase activity and nicotinamide level in human glioma cells. 2010 5
46 18441319 Eight-fold increased risk for congenital heart defects in children carrying the nicotinamide N-methyltransferase polymorphism and exposed to medicines and low nicotinamide. 2008 Jun 2
47 16676400 Histone deacetylase inhibitor depsipeptide represses nicotinamide N-methyltransferase and hepatocyte nuclear factor-1beta gene expression in human papillary thyroid cancer cells. 2006 Feb 2
48 15922112 Nicotinamide homeostasis: a xenobiotic pathway that is key to development and degenerative diseases. 2005 1
49 12727306 High expression of nicotinamide N-methyltransferase in patients with idiopathic Parkinson's disease. 2003 May 15 3
50 14557485 Enhanced expression of nicotinamide N-methyltransferase in human papillary thyroid carcinoma cells. 2003 Oct 1