| 1 |
33405191 | The influence of P-glycoprotein expression in the standard treatment of Helicobacter pylori infection in Sprague Dawley rats. | 2021 Jun |
1 |
| 2 |
32393425 | Effects of cyclosporin A on the pharmacokinetics and toxicities of irinotecan mediated by UGT1A1 in vitro and in vivo. | 2020 May 1 |
1 |
| 3 |
32653591 | Type 2 diabetes mellitus decreases systemic exposure of clopidogrel active metabolite through upregulation of P-glycoprotein in rats. | 2020 Oct |
1 |
| 4 |
30663770 | Baicalin reduces ciclosporin bioavailability by inducing intestinal p-glycoprotein in rats. | 2019 May |
1 |
| 5 |
29530563 | Establishing an in vitro permeation model to predict the in vivo sex-related influence of PEG 400 on oral drug absorption. | 2018 May 5 |
1 |
| 6 |
29703381 | Activation of P-glycoprotein and CYP 3A by Coptidis Rhizoma in vivo: Using cyclosporine as a probe substrate in rats. | 2018 Apr |
7 |
| 7 |
28009901 | Aloe activated P-glycoprotein and CYP 3A: a study on the serum kinetics of aloe and its interaction with cyclosporine in rats. | 2017 Jan 25 |
5 |
| 8 |
28709912 | Excipient-mediated alteration in drug bioavailability in the rat depends on the sex of the animal. | 2017 Sep 30 |
2 |
| 9 |
28917111 | [11C]PF-3274167 as a PET radiotracer of oxytocin receptors: Radiosynthesis and evaluation in rat brain. | 2017 Dec |
1 |
| 10 |
26031900 | Hepatic, gastric and intestinal first-pass effects of vitexin-2''-O-rhamnoside in rats by ultra-high-performance liquid chromatography. | 2016 Feb |
1 |
| 11 |
26972494 | Absorptive interactions of concurrent oral administration of (+)-catechin and puerarin in rats and the underlying mechanisms. | 2016 Apr |
1 |
| 12 |
27000241 | Regulation of P-glycoprotein efflux activity by Z-guggulsterone of Commiphora mukul at the blood-brain barrier. | 2016 Apr 15 |
2 |
| 13 |
27287416 | Increasing nerve agent treatment efficacy by P-glycoprotein inhibition. | 2016 Nov 25 |
1 |
| 14 |
27627555 | The Effect of P-Glycoprotein Inhibition and Activation on the Absorption and Serum Levels of Cyclosporine and Tacrolimus in Rats. | 2016 Mar-Apr |
2 |
| 15 |
25747979 | Enhanced oral bioavailability of morin administered in mixed micelle formulation with PluronicF127 and Tween80 in rats. | 2015 |
3 |
| 16 |
25785492 | Comparative Biodistribution and Pharmacokinetic Analysis of Cyclosporine-A in the Brain upon Intranasal or Intravenous Administration in an Oil-in-Water Nanoemulsion Formulation. | 2015 May 4 |
1 |
| 17 |
25947324 | Effect of cyclosporin on distribution of methotrexate into the brain of rats. | 2015 Sep |
2 |
| 18 |
26329549 | [Molecular Biological Analysis of Factors Influencing Pharmacokinetics to Achieve Personalized Pharmacotherapy]. | 2015 |
4 |
| 19 |
24502637 | Effects of serum lipoproteins on cyclosporine A cellular uptake and renal toxicity in vitro. | 2014 Feb |
1 |
| 20 |
24555822 | P-glycoprotein (P-gp)-mediated efflux limits intestinal absorption of the Hsp90 inhibitor SNX-2112 in rats. | 2014 Aug |
1 |
| 21 |
25310383 | Potent nonimmunosuppressive cyclophilin inhibitors with improved pharmaceutical properties and decreased transporter inhibition. | 2014 Oct 23 |
1 |
| 22 |
23791640 | Functional characterization of hepatic transporters using intravital microscopy. | 2013 Aug 16 |
3 |
| 23 |
24013073 | Capsaicin pretreatment increased the bioavailability of cyclosporin in rats: involvement of P-glycoprotein and CYP 3A inhibition. | 2013 Dec |
1 |
| 24 |
24090809 | CJY, an isoflavone, interacts with ATPase of P-glycoprotein in the rat brain microvessel endothelial cells (RBMECs). | 2013 Dec |
2 |
| 25 |
21869731 | Kidney-specific deletion of multidrug resistance-related protein 2 does not aggravate acute cyclosporine A nephrotoxicity in rats. | 2012 Jun |
2 |
| 26 |
22079035 | Studies of the myocardial uptake and excretion mechanisms of a novel 99mTc heart perfusion agent. | 2012 Feb |
3 |
| 27 |
22169469 | In vivo microdialysis with LC-MS for analysis of spinosin and its interaction with cyclosporin A in rat brain, blood and bile. | 2012 Mar 5 |
1 |
| 28 |
22316009 | P-glycoprotein-based loperamide-cyclosporine drug interaction at the rat blood-brain barrier: prediction from in vitro studies and extrapolation to humans. | 2012 Mar 5 |
1 |
| 29 |
22361031 | Encapsulation of P-glycoprotein inhibitors by polymeric micelles can reduce their pharmacokinetic interactions with doxorubicin. | 2012 May |
2 |
| 30 |
22749977 | An antioxidant Trolox restores decreased oral absorption of cyclosporine A after liver ischemia-reperfusion through distinct mechanisms between CYP3A and P-glycoprotein in the small intestine. | 2012 Sep 5 |
6 |
| 31 |
22764568 | Characterization of intestinal absorption of quinidine, a P-glycoprotein substrate, given as a powder in rats. | 2012 May |
1 |
| 32 |
21421030 | Danshen extract does not alter pharmacokinetics of docetaxel and clopidogrel, reflecting its negligible potential in P-glycoprotein- and cytochrome P4503A-mediated herb-drug interactions. | 2011 May 30 |
1 |
| 33 |
21737631 | P-glycoprotein modulation by valspodar and cyclosporin does not increase tumor uptake of doxorubicin administered via isolated lung perfusion to rats bearing sarcoma lung metastases. | 2011 Jun |
2 |
| 34 |
22115032 | An in vitro transport model for rapid screening and predicting the permeability of candidate compounds at blood-brain barrier. | 2011 Dec |
1 |
| 35 |
18842703 | Decreased oral absorption of cyclosporine A after liver ischemia-reperfusion injury in rats: the contribution of CYP3A and P-glycoprotein to the first-pass metabolism in intestinal epithelial cells. | 2009 Jan |
1 |
| 36 |
18855917 | A comparison of the effects of p-glycoprotein inhibitors on the blood-brain barrier permeation of cyclic prodrugs of an opioid peptide (DADLE). | 2009 Jun |
2 |
| 37 |
18985346 | Effect of cyclosporin A administration on the biodistribution and multipinhole muSPECT imaging of [123I]R91150 in rodent brain. | 2009 Mar |
1 |
| 38 |
19013229 | Development and characterisation of a new model of rat trophoblasts. | 2009 Feb |
1 |
| 39 |
19111511 | Pharmacokinetics of kadsurenone and its interaction with cyclosporin A in rats using a combined HPLC and microdialysis system. | 2009 Jan 15 |
1 |
| 40 |
19746191 | Synthesis, radiosynthesis and in vivo evaluation of [I]-4-(2-(bis(4-fluorophenyl)methoxy)ethyl)-1-(4-iodobenzyl)piperidine as a selective tracer for imaging the dopamine transporter. | 2009 May 28 |
2 |
| 41 |
19819100 | Effect of cyclosporine on drug transport and pharmacokinetics of nifedipine. | 2009 Nov |
4 |
| 42 |
19951574 | P-glycoprotein regulating biphasic insulin secretion in rat pancreatic beta cells. | 2009 Nov 5 |
2 |
| 43 |
18424002 | Increased amyloid beta-peptide (1-40) level in brain of streptozotocin-induced diabetic rats. | 2008 May 15 |
1 |
| 44 |
18482683 | Can celecoxib affect P-glycoprotein-mediated drug efflux? A microPET study. | 2008 May |
3 |
| 45 |
18485890 | Regulation of brain endothelial cells migration and angiogenesis by P-glycoprotein/caveolin-1 interaction. | 2008 Aug 1 |
1 |
| 46 |
18540481 | Investigation of the intestinal permeability of ciclosporin using the in situ technique in rats and the relevance of P-glycoprotein. | 2008 |
2 |
| 47 |
18604533 | Cyclosporine, a P-glycoprotein modulator, increases [18F]MPPF uptake in rat brain and peripheral tissues: microPET and ex vivo studies. | 2008 Dec |
3 |
| 48 |
18725544 | Contribution of down-regulation of intestinal and hepatic cytochrome P450 3A to increased absorption of cyclosporine A in a rat nephrosis model. | 2008 Nov |
1 |
| 49 |
18817631 | Effects of cyclosporin A and itraconazole on the pharmacokinetics of atorvastatin in rats. | 2008 Oct |
1 |
| 50 |
19356088 | Effects of cyclosporine A and itraconazole on permeability, biliary excretion and pharmacokinetics of amlodipine. | 2008 Aug |
4 |