Fatty Acids, Unsaturated

arachidonate 15-lipoxygenase ; Homo sapiens







26 Article(s)
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Pub. Year
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1 35577309 Functional and pathological role of 15-Lipoxygenase and its metabolites in pregnancy and pregnancy-associated complications. 2022 Aug 1
2 34486255 Arachidonic Acid 15-Lipoxygenase: Effects of Its Expression, Metabolites, and Genetic and Epigenetic Variations on Airway Inflammation. 2021 Sep 1
3 34655995 Novel role of xanthine oxidase-dependent H2O2 production in 12/15-lipoxygenase-mediated de novo lipogenesis, triglyceride biosynthesis and weight gain. 2021 Nov 2
4 34838055 15-Lipoxygenase and its metabolites in the pathogenesis of breast cancer: A double-edged sword. 2021 Nov 27 1
5 33038835 Double lipoxygenation of polyunsaturated fatty acids of nutritional interest. 2020 Nov 2
6 33396527 Mechanistic Insight into the Regulation of Lipoxygenase-Driven Lipid Peroxidation Events in Human Spermatozoa and Their Impact on Male Fertility. 2020 Dec 31 1
7 30347209 Role of the 12-lipoxygenase pathway in diabetes pathogenesis and complications. 2019 Mar 2
8 30472260 Emerging role of 12/15-Lipoxygenase (ALOX15) in human pathologies. 2019 Jan 2
9 31231138 Replacement of an Indole Scaffold Targeting Human 15-Lipoxygenase-1 Using Combinatorial Chemistry. 2019 May 2
10 31717983 Deficiency of 15-LOX-1 Induces Radioresistance through Downregulation of MacroH2A2 in Colorectal Cancer. 2019 Nov 11 2
11 31903039 12/15 Lipoxygenase as a Therapeutic Target in Brain Disorders. 2019 Dec 2
12 29235036 Expression of DHA-Metabolizing Enzyme Alox15 is Regulated by Selective Histone Acetylation in Neuroblastoma Cells. 2018 Mar 1
13 29546268 Pharmacological inhibition of arachidonate 15-lipoxygenase protects human spermatozoa against oxidative stress. 2018 Jun 1 2
14 29627380 12/15 lipoxygenase: A crucial enzyme in diverse types of cell death. 2018 Sep 2
15 29882120 The importance of 15-lipoxygenase inhibitors in cancer treatment. 2018 Sep 2
16 30197642 A Novel Function for 15-Lipoxygenases in Cholesterol Homeostasis and CCL17 Production in Human Macrophages. 2018 2
17 27480217 The double-edged role of 12/15-lipoxygenase during inflammation and immunity. 2017 Apr 2
18 28400162 Mammalian ALOX15 orthologs exhibit pronounced dual positional specificity with docosahexaenoic acid. 2017 Jul 2
19 27647374 Human 15-LOX-1 active site mutations alter inhibitor binding and decrease potency. 2016 Nov 1 1
20 24465480 Interleukin-4-mediated 15-lipoxygenase-1 trans-activation requires UTX recruitment and H3K27me3 demethylation at the promoter in A549 cells. 2014 1
21 23055198 Induction of apoptosis by Trichostatin A in human breast cancer cell lines: involvement of 15-Lox-1. 2013 Feb 2
22 23285160 Transcriptional regulation of 15-lipoxygenase expression by histone h3 lysine 4 methylation/demethylation. 2012 2
23 20581078 Development of a fluorescent intensity assay amenable for high-throughput screening for determining 15-lipoxygenase activity. 2010 Jul 1
24 15572846 [Leukotriene-lipoxygenase pathway and drug discovery]. 2004 Dec 2
25 11966935 Local application of n-3 or n-6 polyunsaturated fatty acids in the treatment of human experimental gingivitis. 2002 Apr 1
26 7615823 Lipoxygenase contributes to the oxidation of lipids in human atherosclerotic plaques. 1995 Jul 2