| 1 |
34963632 | Effects of 15-lipoxygenase overexpressing adipose tissue mesenchymal stem cells on the Th17 / Treg plasticity. | 2022 Apr |
2 |
| 2 |
35531094 | The Reaction Specificity of Mammalian ALOX15 Orthologs is Changed During Late Primate Evolution and These Alterations Might Offer Evolutionary Advantages for Hominidae. | 2022 |
3 |
| 3 |
32627384 | Eicosanoid biosynthesis in marine mammals. | 2021 Feb |
2 |
| 4 |
32867639 | The Emerging Role of COX-2, 15-LOX and PPARγ in Metabolic Diseases and Cancer: An Introduction to Novel Multi-target Directed Ligands (MTDLs). | 2021 |
2 |
| 5 |
33450390 | COX-1 dependent biosynthesis of 15-hydroxyeicosatetraenoic acid in human mast cells. | 2021 May |
2 |
| 6 |
33662546 | Oxygenation of endocannabinoids by mammalian lipoxygenase isoforms. | 2021 Jun |
2 |
| 7 |
34033145 | High levels of eicosanoids and docosanoids in the lungs of intubated COVID-19 patients. | 2021 Jun |
1 |
| 8 |
34474105 | Stress-activated leukocyte 12/15-lipoxygenase metabolite enhances struggle behaviour and tocotrienols relieve stress-induced behaviour alteration. | 2021 Nov 1 |
1 |
| 9 |
34486255 | Arachidonic Acid 15-Lipoxygenase: Effects of Its Expression, Metabolites, and Genetic and Epigenetic Variations on Airway Inflammation. | 2021 Sep |
1 |
| 10 |
32488442 | Bioconversion of arachidonic acid into human 14,15-hepoxilin B3 and 13,14,15-trioxilin B3 by recombinant cells expressing microbial 15-lipoxygenase without and with epoxide hydrolase. | 2020 Oct |
1 |
| 11 |
32564168 | Correction to: Bioconversion of arachidonic acid into human 14,15-hepoxilin B3 and 13,14,15-trioxilin B3 by recombinant cells expressing microbial 15-lipoxygenase without and with epoxide hydrolase. | 2020 Oct |
1 |
| 12 |
33182324 | Influence of Lipoxygenase Inhibition on Glioblastoma Cell Biology. | 2020 Nov 9 |
2 |
| 13 |
33396527 | Mechanistic Insight into the Regulation of Lipoxygenase-Driven Lipid Peroxidation Events in Human Spermatozoa and Their Impact on Male Fertility. | 2020 Dec 31 |
1 |
| 14 |
30347209 | Role of the 12-lipoxygenase pathway in diabetes pathogenesis and complications. | 2019 Mar |
2 |
| 15 |
30452122 | Inhibition of arachidonate 15-lipoxygenase reduces the epithelial-mesenchymal transition in eosinophilic chronic rhinosinusitis with nasal polyps. | 2019 Mar |
2 |
| 16 |
30599203 | Functional characterization of novel ALOX15 orthologs representing key steps in mammalian evolution supports the Evolutionary Hypothesis of reaction specificity. | 2019 Mar |
1 |
| 17 |
31333453 | Regulation and Functions of 15-Lipoxygenases in Human Macrophages. | 2019 |
1 |
| 18 |
29154477 | Mutagenesis of Sequence Determinants of Truncated Porcine ALOX15 Induces Changes in the Reaction Specificity by Altering the Catalytic Mechanism of Initial Hydrogen Abstraction. | 2018 Jan 19 |
1 |
| 19 |
29772700 | Inhibition of Arachidonate 12/15-Lipoxygenase Improves α-Galactosidase Efficacy in iPSC-Derived Cardiomyocytes from Fabry Patients. | 2018 May 16 |
2 |
| 20 |
30138423 | Hypoxic cardiac fibroblasts from failing human hearts decrease cardiomyocyte beating frequency in an ALOX15 dependent manner. | 2018 |
1 |
| 21 |
28011194 | Convergence of eicosanoid and integrin biology: Role of Src in 12-LOX activation. | 2017 Feb 1 |
2 |
| 22 |
28400162 | Mammalian ALOX15 orthologs exhibit pronounced dual positional specificity with docosahexaenoic acid. | 2017 Jul |
1 |
| 23 |
28809482 | Structural Dynamics of 15-Lipoxygenase-2 via Hydrogen-Deuterium Exchange. | 2017 Sep 26 |
2 |
| 24 |
26290290 | Discovery of Novel 15-Lipoxygenase Activators To Shift the Human Arachidonic Acid Metabolic Network toward Inflammation Resolution. | 2016 May 12 |
3 |
| 25 |
26560362 | 15-Lipoxygenase inhibitors: a patent review. | 2016 |
1 |
| 26 |
27552229 | The Arachidonate 15-Lipoxygenase Enzyme Product 15-HETE Is Present in Heart Tissue from Patients with Ischemic Heart Disease and Enhances Clot Formation. | 2016 |
1 |
| 27 |
27580047 | Motions of Allosteric and Orthosteric Ligand-Binding Sites in Proteins are Highly Correlated. | 2016 Sep 26 |
1 |
| 28 |
26194111 | The role of 15-LOX-1 in colitis and colitis-associated colorectal cancer. | 2015 Sep |
1 |
| 29 |
26276392 | AMP-activated protein kinase suppresses arachidonate 15-lipoxygenase expression in interleukin 4-polarized human macrophages. | 2015 Oct 2 |
2 |
| 30 |
24786190 | Liquid chromatography-tandem mass spectrometry for simultaneous measurement of thromboxane B2 and 12(S)-hydroxyeicosatetraenoic acid in serum. | 2014 Aug 5 |
2 |
| 31 |
25036362 | Maresin biosynthesis and identification of maresin 2, a new anti-inflammatory and pro-resolving mediator from human macrophages. | 2014 |
1 |
| 32 |
23394536 | Lipoxygenase: an emerging target for stroke therapy. | 2013 Mar |
2 |
| 33 |
23838566 | 12/15-lipoxygenase expression is increased in oligodendrocytes and microglia of periventricular leukomalacia. | 2013 |
1 |
| 34 |
24669684 | [The role and clinical significance of 12-LOX passway in arachidonic acid metabolism induced by phospholipase Cgamma-2 in laryngeal squamous cell carcinoma]. | 2013 Dec |
1 |
| 35 |
22155783 | Protein kinase C regulation of 12-lipoxygenase-mediated human platelet activation. | 2012 Mar |
3 |
| 36 |
22516296 | Conversion of human 5-lipoxygenase to a 15-lipoxygenase by a point mutation to mimic phosphorylation at Serine-663. | 2012 Aug |
1 |
| 37 |
22973824 | Eliminating or blocking 12/15-lipoxygenase reduces neutrophil recruitment in mouse models of acute lung injury. | 2012 Sep 13 |
2 |
| 38 |
22982617 | Reciprocal regulation of HIF-1α and 15-LO/15-HETE promotes anti-apoptosis process in pulmonary artery smooth muscle cells during hypoxia. | 2012 Dec |
1 |
| 39 |
20822476 | The role of ERK1/2 in 15-HETE-inhibited apoptosis in pulmonary arterial smooth muscle cells. | 2011 Feb |
1 |
| 40 |
21540548 | Lipoxygenase mediates invasion of intrametastatic lymphatic vessels and propagates lymph node metastasis of human mammary carcinoma xenografts in mouse. | 2011 May |
1 |
| 41 |
19911203 | Binding of arachidonic acid and two flavonoid inhibitors to human 12- and 15-lipoxygenases: a steered molecular dynamics study. | 2010 May |
2 |
| 42 |
20599608 | Role of 12/15-lipoxygenase in nitrosative stress and peripheral prediabetic and diabetic neuropathies. | 2010 Sep 15 |
1 |
| 43 |
20619278 | 15-Hydroxyeicosatetraenoic acid (15-HETE) protects pulmonary artery smooth muscle cells against apoptosis via HSP90. | 2010 Aug 14 |
1 |
| 44 |
20653566 | Thrombin-activated human platelets acutely generate oxidized docosahexaenoic-acid-containing phospholipids via 12-lipoxygenase. | 2010 Oct 1 |
2 |
| 45 |
20826080 | Selenoprotein P protects cells from lipid hydroperoxides generated by 15-LOX-1. | 2010 Oct-Dec |
1 |
| 46 |
18494609 | Effects of (15S)-hydroperoxyeicosatetraenoic acid and (15S)-hydroxyeicosatetraenoic acid on the acute- lymphoblastic-leukaemia cell line Jurkat: activation of the Fas-mediated death pathway. | 2009 Feb |
2 |
| 47 |
19235890 | Vitamin K prevents oxidative cell death by inhibiting activation of 12-lipoxygenase in developing oligodendrocytes. | 2009 Jul |
4 |
| 48 |
19535459 | 15-oxo-Eicosatetraenoic acid, a metabolite of macrophage 15-hydroxyprostaglandin dehydrogenase that inhibits endothelial cell proliferation. | 2009 Sep |
1 |
| 49 |
19576981 | A 4-oxo-2(E)-nonenal-derived glutathione adduct from 15-lipoxygenase-1-mediated oxidation of cytosolic and esterified arachidonic acid. | 2009 Oct 1 |
1 |
| 50 |
19736311 | Src-dependent STAT-3-mediated expression of monocyte chemoattractant protein-1 is required for 15(S)-hydroxyeicosatetraenoic acid-induced vascular smooth muscle cell migration. | 2009 Nov 6 |
1 |