pyrazole

cytochrome P450, family 2, subfamily e, polypeptide 1 ; Rattus norvegicus







29 Article(s)
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1 17436021 Hepatic morphological alterations, glycogen content and cytochrome P450 activities in rats treated chronically with N(omega)-nitro-L-arginine methyl ester (L-NAME). 2007 Jul 1
2 17640612 Depletion of S-adenosyl-l-methionine with cycloleucine potentiates cytochrome P450 2E1 toxicity in primary rat hepatocytes. 2007 Oct 15 1
3 16306132 Opposite action of S-adenosyl methionine and its metabolites on CYP2E1-mediated toxicity in pyrazole-induced rat hepatocytes and HepG2 E47 cells. 2006 Apr 1
4 16652227 Expression of constitutive and inducible cytochrome P450 2E1 in rat brain. 2006 Jun 1
5 16962935 Increased toxicity by transforming growth factor-beta 1 in liver cells overexpressing CYP2E1. 2006 Oct 1 1
6 15845871 Lipopolysaccharide-induced liver injury in rats treated with the CYP2E1 inducer pyrazole. 2005 Aug 5
7 12500194 Cytochrome P450 2E1 responsiveness in the promoter of glutamate-cysteine ligase catalytic subunit. 2003 Jan 1
8 12529372 Increased Sp1-dependent transactivation of the LAMgamma 1 promoter in hepatic stellate cells co-cultured with HepG2 cells overexpressing cytochrome P450 2E1. 2003 Apr 25 1
9 12774019 Proteasome inhibition potentiates CYP2E1-mediated toxicity in HepG2 cells. 2003 Jun 1
10 12777398 Increased expression of cytochrome P450 2E1 induces heme oxygenase-1 through ERK MAPK pathway. 2003 Aug 8 1
11 11782477 Cytochrome P450 2E1-derived reactive oxygen species mediate paracrine stimulation of collagen I protein synthesis by hepatic stellate cells. 2002 Mar 22 2
12 11259624 Sodium salicylate increases CYP2E1 levels and enhances arachidonic acid toxicity in HepG2 cells and cultured rat hepatocytes. 2001 Apr 1
13 11325963 Mitochondrial targeted cytochrome P450 2E1 (P450 MT5) contains an intact N terminus and requires mitochondrial specific electron transfer proteins for activity. 2001 Jul 6 1
14 11562436 Synergistic toxicity of iron and arachidonic acid in HepG2 cells overexpressing CYP2E1. 2001 Oct 1
15 10718635 Ethanol and arachidonic acid produce toxicity in hepatocytes from pyrazole-treated rats with high levels of CYP2E1. 2000 Jan 2
16 9952314 The high-affinity binding of [3H]norharman ([3H]beta-carboline) to the ethanol-inducible cytochrome P450 2E1 in rat liver. 1999 Mar 1 1
17 9016819 Inhibition of rat and human cytochrome P4502E1 catalytic activity and reactive oxygen radical formation by nitric oxide. 1997 Jan 15 1
18 9354595 Noninvolvement of CYP2E1 in the (omega-1)-hydroxylation of fatty acids in rat kidney microsomes. 1997 Oct 15 2
19 9363841 Undernutrition during hyperoxic exposure induces CYP2E1 in rat liver. 1997 1
20 8961948 Thiol oxidation and cytochrome P450-dependent metabolism of CCl4 triggers Ca2+ release from liver microsomes. 1996 Dec 10 1
21 7488011 Increased production of hydroxyl radical by pericentral microsomes compared to periportal microsomes after pyrazole induction of cytochrome P4502E1. 1995 Oct 13 2
22 8093035 Evidence that cytochrome P450 2E1 is involved in the (omega-1)-hydroxylation of lauric acid in rat liver microsomes. 1994 Sep 15 1
23 8208127 Evaluation of pyrazole and ethanol induced S9 fraction in bacterial mutagenicity testing. 1994 Jan 1
24 1329733 Differential oxidase activity of hepatic and pulmonary microsomal cytochrome P-450 isozymes after treatment with cytochrome P-450 inducers. 1992 Sep 30 1
25 2306278 Oxidation of glycerol to formaldehyde by rat liver microsomes. Effects of cytochrome P-450 inducing agents. 1990 Feb 15 1
26 2766463 Immunochemical characterization of cytochrome P-450 isozymes responsible for benzene oxidation in the rat liver. 1989 Sep 2
27 3223429 Structure and regulation of the ethanol-inducible cytochrome P450j. 1988 1
28 3113478 Regulation of cytochrome P-450j, a high-affinity N-nitrosodimethylamine demethylase, in rat hepatic microsomes. 1987 Apr 21 1
29 3782137 Complementary DNA and protein sequences of ethanol-inducible rat and human cytochrome P-450s. Transcriptional and post-transcriptional regulation of the rat enzyme. 1986 Dec 15 1