Testosterone

cytochrome P450, subfamily 2, polypeptide 11 ; Rattus norvegicus







44 Article(s)
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1 24942648 Irreversible perinatal imprinting of adult expression of the principal sex-dependent drug-metabolizing enzyme CYP2C11. 2014 Sep 1
2 22271348 Mass spectrometric detection of CYP450 adducts following oxidative desulfuration of methyl parathion. 2013 Jul 1
3 23924605 The role of brain noradrenergic system in the regulation of liver cytochrome P450 expression. 2013 Sep 15 2
4 22358097 Effect of neuroleptics on cytochrome P450 2C11 (CYP2C11) in rat liver. 2011 2
5 19219745 Development of an optimized procedure for the preparation of rat intestinal microsomes: comparison of hepatic and intestinal microsomal cytochrome P450 enzyme activities in two rat strains. 2009 Jan 1
6 17523050 Cytochrome P450 probe substrate metabolism kinetics in Sprague Dawley rats. 2007 May 1
7 16382210 Direct effects of neuroleptics on the activity of CYP2A in the liver of rats. 2005 Nov-Dec 1
8 15114436 Effect of bisphenol A on drug metabolising enzymes in rat hepatic microsomes and precision-cut rat liver slices. 2004 Jul 1
9 12933671 Effects of chronic ethanol on hepatic and renal CYP2C11 in the male rat: interactions with the Janus-kinase 2-signal transducer and activators of transcription proteins 5b pathway. 2003 Sep 1
10 14555335 Mechanism-based inhibition of CYP activities in rat liver by fluoxetine and structurally similar alkylamines. 2003 Oct 1
11 14595850 Perinatal exposure to low doses of 2,3,7,8-tetrachlorodibenzo-p-dioxin alters sex-dependent expression of hepatic CYP2C11. 2003 1
12 12029382 Sensitive detection of the endocrine effects of the estrogen analogue ethinylestradiol using a modified enhanced subacute rat study protocol (OECD Test Guideline no. 407). 2002 May 1
13 11312643 Effect of hypophysectomy and growth hormone replacement on the modulation of p450 expression after treatment with the aromatic hydrocarbon ethylbenzene. 2001 May 1 1
14 11354908 Feasibility and potential gains of enhancing the subacute rat study protocol (OECD test guideline no. 407) by additional parameters selected to determine endocrine modulation. A pre-validation study to determine endocrine-mediated effects of the antiandrogenic drug flutamide. 2001 Apr 1
15 11724755 Differential regulation of endobiotic-oxidizing cytochromes P450 in vitamin A-deficient male rat liver. 2001 Dec 1
16 10698668 Interference with growth hormone stimulation of hepatic cytochrome P4502C11 expression in hypophysectomized male rats by 3-methylcholanthrene. 2000 Mar 1 1
17 10773843 Glucocorticoid-dependent maintenance of CYP2C11-dependent oxidation in male rat liver in vivo. 2000 Feb 1
18 11082433 Sequence analyses of CYP2B genes and catalytic profiles for P450s in Qdj:Sprague-dawley rats that lack response to the phenobarbital-mediated induction of CYP2B2. 2000 Dec 1
19 9882461 Nonsubstrate recognition site residues are involved in testosterone hydroxylation by cytochrome P450 CYP 2C11. 1999 Jan 15 2
20 9890448 Identification of the cytochrome P450 isoenzymes involved in the metabolism of diazinon in the rat liver. 1999 2
21 10447797 Testosterone metabolism in rat brain is differentially enhanced by phenytoin-inducible cytochrome P450 isoforms. 1999 Aug 1
22 10460793 Modulation of rat cytochrome P-450 by an investigational HIV protease inhibitor. 1999 Sep 1
23 9531521 Dihydralazine-induced inactivation of cytochrome P450 enzymes in rat liver microsomes. 1998 Apr 1
24 9763410 Effect of androgen administration during puberty on hepatic CYP2C11, CYP3A, and CYP2A1 expression in adult female rats. 1998 Oct 2
25 9103546 Phencyclidine continuous dosing produces a treatment time-dependent regulation of rat CYP2C11 function, protein expression and mRNA levels. 1997 Apr 1
26 8573203 Impact of tamoxifen on peripubertal androgen imprinting of rat hepatic cytochrome P450 2C11, cytochrome P450 3A2, and steroid 5 alpha-reductase. 1996 Feb 9 1
27 8611037 cDNA-directed expression of two allelic variants of cytochrome P450 2C11 using COS1 and SF21 insect cells. 1996 Feb 15 3
28 8619245 Reproductive toxicity and growth effects in rats exposed to lead at different periods during development. 1996 Feb 1
29 8666339 Persistent sex differences in growth control of early rat liver lesions are programmed during promotion in the resistant hepatocyte model. 1996 Apr 1
30 8694846 Effects of metyrapone on expression of CYPs 2C11, 3A2, and other 3A genes in rat hepatocytes cultured on matrigel. 1996 Jul 26 2
31 8819526 Peripubertal androgen imprinting of rat hepatic cytochrome P450 2C11 and steroid 5 alpha-reductase: pretranslational regulation and impact on microsomal drug activation. 1996 Sep 3
32 7635428 Downregulation of male-specific cytochrome P450s 2C11 and 3A2 in bile duct-ligated male rats: importance to reduced hepatic content of cytochrome P450 in cholestasis. 1995 Aug 1
33 7839362 Xenobiotic metabolizing enzyme activities and viability are well preserved in EDTA-isolated rat liver parenchymal cells after cryopreservation. 1995 Jan 1
34 7681658 Monoclonal antibodies of differentiating specificities as probes of cytochrome P450h (2C11). 1993 Mar 1
35 8274026 Expression of a male-specific cytochrome P450 isozyme (CYP2C11) in fa/fa Zucker rats: effect of phenobarbital treatment. 1993 Dec 2
36 8495410 Cyclophosphamide modulates rat hepatic cytochrome P450 2C11 and steroid 5 alpha-reductase activity and messenger RNA levels through the combined action of acrolein and phosphoramide mustard. 1993 Jun 1 1
37 1472535 Alteration of cytochrome P-450 2C11-dependent testosterone metabolism in Gunn rat liver. 1992 Dec 8 4
38 2325409 Pronounced and differential effects of ionic strength and pH on testosterone oxidation by membrane-bound and purified forms of rat liver microsomal cytochrome P-450. 1990 Mar 5
39 2752981 Identification of the cytochrome P-450 isozymes responsible for testosterone oxidation in rat lung, kidney, and testis: evidence that cytochrome P-450a (P450IIA1) is the physiologically important testosterone 7 alpha-hydroxylase in rat testis. 1989 Aug 2
40 3592665 Regulation of testosterone hydroxylation by rat liver microsomal cytochrome P-450. 1987 May 15 1
41 3689827 Purification and characterization of liver microsomal cytochrome P-450 from untreated male rats. 1987 Dec 7 1
42 2434473 Purification and characterization of three male-specific and one female-specific forms of cytochrome P-450 from rat liver microsomes. 1986 Nov 1
43 3516654 17 beta-estradiol 2- and 4-hydroxylation catalyzed by rat hepatic cytochrome P-450: roles of individual forms, inductive effects, developmental patterns, and alterations by gonadectomy and hormone replacement. 1986 May 1
44 6420404 Characterization of three highly purified cytochromes P-450 from hepatic microsomes of adult male rats. 1984 Jan 25 1