Guanine Nucleotides

cell division cycle 42 ; Homo sapiens







86 Article(s)
Download
PMID
Title
Pub. Year
#Total Relationships
1 35203342 Impaired Function of PLEKHG2, a Rho-Guanine Nucleotide-Exchange Factor, Disrupts Corticogenesis in Neurodevelopmental Phenotypes. 2022 Feb 16 1
2 35290799 Parallel kinase pathways stimulate actin polymerization at depolarized mitochondria. 2022 Apr 11 1
3 35174167 Role of ARHGEF3 as a GEF and mTORC2 Regulator. 2021 1
4 32086369 Cdc42 Mediates Cancer Cell Chemotaxis in Perineural Invasion. 2020 Jun 1
5 32188698 ARHGEF7 (β-PIX) Is Required for the Maintenance of Podocyte Architecture and Glomerular Function. 2020 May 1
6 32322580 Targeting Rac and Cdc42 GEFs in Metastatic Cancer. 2020 1
7 32681954 Characterization of guanine nucleotide exchange activity of DH domain of human FGD2. 2020 Dec 2
8 32726583 A modified method for preparation of fluorescent MantGDP bound CDC42. 2020 Dec 1 1
9 28489964 Specific activation of PLEKHG2-induced serum response element-dependent gene transcription by four-and-a-half LIM domains (FHL) 1, but not FHL2 or FHL3. 2019 Sep 1
10 30853411 Structural Basis for the Dual Substrate Specificity of DOCK7 Guanine Nucleotide Exchange Factor. 2019 May 7 1
11 31089935 DBS is activated by EPHB2/SRC signaling-mediated tyrosine phosphorylation in HEK293 cells. 2019 Sep 1
12 29130632 DOCK3-related neurodevelopmental syndrome: Biallelic intragenic deletion of DOCK3 in a boy with developmental delay and hypotonia. 2018 Jan 1
13 29773874 Mutations in six nephrosis genes delineate a pathogenic pathway amenable to treatment. 2018 May 17 1
14 29858187 Targeting Rac and Cdc42 GTPases in Cancer. 2018 Jun 15 1
15 30446664 Optogenetic dissection of Rac1 and Cdc42 gradient shaping. 2018 Nov 16 1
16 27669437 The focal adhesion-associated proteins DOCK5 and GIT2 comprise a rheostat in control of epithelial invasion. 2017 Mar 30 1
17 28029388 Emerging role of Cdc42-specific guanine nucleotide exchange factors as regulators of membrane trafficking in health and disease. 2017 Apr 1
18 28600358 Cell adhesion controlled by adhesion G protein-coupled receptor GPR124/ADGRA2 is mediated by a protein complex comprising intersectins and Elmo-Dock. 2017 Jul 21 1
19 26542736 Guanine nucleotide induced conformational change of Cdc42 revealed by hydrogen/deuterium exchange mass spectrometry. 2016 Jan 1
20 27182061 Expanding functions of GIT Arf GTPase-activating proteins, PIX Rho guanine nucleotide exchange factors and GIT-PIX complexes. 2016 May 15 1
21 27693507 Cell-Intrinsic Adaptation Arising from Chronic Ablation of a Key Rho GTPase Regulator. 2016 Oct 10 1
22 27765816 Four-and-a-half LIM Domains 1 (FHL1) Protein Interacts with the Rho Guanine Nucleotide Exchange Factor PLEKHG2/FLJ00018 and Regulates Cell Morphogenesis. 2016 Nov 25 1
23 26056138 KCC2 regulates actin dynamics in dendritic spines via interaction with β-PIX. 2015 Jun 8 1
24 22543585 Rescue of glandular dysmorphogenesis in PTEN-deficient colorectal cancer epithelium by PPARγ-targeted therapy. 2013 Mar 7 1
25 23197258 SLAT regulates CD8+ T cell clonal expansion in a Cdc42- and NFAT1-dependent manner. 2013 Jan 1 1
26 23382385 Characterization of a Cdc42 protein inhibitor and its use as a molecular probe. 2013 Mar 22 1
27 23718289 Prenylation and membrane localization of Cdc42 are essential for activation by DOCK7. 2013 Jun 25 3
28 23941980 Association of Asef and Cdc42 expression to tubular injury in diseased human kidney. 2013 Oct 2
29 24563715 Dock protein family in brain development and neurological disease. 2013 Nov 1 1
30 22362774 Structure of Salmonella effector protein SopB N-terminal domain in complex with host Rho GTPase Cdc42. 2012 Apr 13 3
31 22596063 The association between CDC42 and caveolin-1 is involved in the regulation of capacitation and acrosome reaction of guinea pig and mouse sperm. 2012 Jul 1
32 22829599 DEF6, a novel substrate for the Tec kinase ITK, contains a glutamine-rich aggregation-prone region and forms cytoplasmic granules that co-localize with P-bodies. 2012 Sep 7 1
33 21295482 Control of local Rho GTPase crosstalk by Abr. 2011 Feb 22 1
34 22126964 A targeted siRNA screen identifies regulators of Cdc42 activity at the natural killer cell immunological synapse. 2011 Nov 29 1
35 20228056 Co-regulation of caveolar and Cdc42-dependent fluid phase endocytosis by phosphocaveolin-1. 2010 May 14 1
36 20842712 Autoinhibition of GEF activity in Intersectin 1 is mediated by the short SH3-DH domain linker. 2010 Nov 1
37 19356586 Characterisation of the nucleotide exchange factor ITSN1L: evidence for a kinetic discrimination of GEF-stimulated nucleotide release from Cdc42. 2009 Mar 27 1
38 19435813 Host deficiency in Vav2/3 guanine nucleotide exchange factors impairs tumor growth, survival, and angiogenesis in vivo. 2009 May 1
39 19525225 Adenomatous polyposis coli and Asef function downstream of hepatocyte growth factor and phosphatidylinositol 3-kinase. 2009 Aug 14 1
40 18056264 Specific recognition of Rac2 and Cdc42 by DOCK2 and DOCK9 guanine nucleotide exchange factors. 2008 Feb 8 1
41 18208356 Smurf1 directly targets hPEM-2, a GEF for Cdc42, via a novel combination of protein interaction modules in the ubiquitin-proteasome pathway. 2008 Apr 1
42 18267089 Rho-kinase phosphorylates PAR-3 and disrupts PAR complex formation. 2008 Feb 1
43 18299239 The PIX-GIT complex: a G protein signaling cassette in control of cell shape. 2008 Jun 1
44 18331715 Nudel binds Cdc42GAP to modulate Cdc42 activity at the leading edge of migrating cells. 2008 Mar 1
45 18410521 Frabin and other related Cdc42-specific guanine nucleotide exchange factors couple the actin cytoskeleton with the plasma membrane. 2008 Aug 1
46 18596235 The DHR1 domain of DOCK180 binds to SNX5 and regulates cation-independent mannose 6-phosphate receptor transport. 2008 Sep 1
47 17538024 Activated ezrin promotes cell migration through recruitment of the GEF Dbl to lipid rafts and preferential downstream activation of Cdc42. 2007 Aug 2
48 16337026 AlphaPIX and betaPIX and their role in focal adhesion formation. 2006 Apr 1
49 16616186 The crystal structure of Cdc42 in complex with collybistin II, a gephyrin-interacting guanine nucleotide exchange factor. 2006 May 26 1
50 17128987 Redox regulation of RhoA. 2006 Dec 5 1