Adenosine

adenosine A2a receptor ; Mus musculus







117 Article(s)
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1 34536482 Positive Allosteric Modulation of A2AR Alters Immune Cell Responses and Ameliorates Psoriasis-Like Dermatitis in Mice. 2022 Mar 2
2 34813840 Blockade of adenosine A2A receptor alleviates cognitive dysfunction after chronic exposure to intermittent hypoxia in mice. 2022 Apr 1
3 34846650 Exogenous adenosine activates A2A adenosine receptor to inhibit RANKL-induced osteoclastogenesis via AP-1 pathway to facilitate bone repair. 2022 Mar 2
4 35597366 Crosstalk between adenosine receptors and CYP450-derived oxylipins in the modulation of cardiovascular, including coronary reactive hyperemic response. 2022 May 18 3
5 33333075 Use of knockout mice to explore CNS effects of adenosine. 2021 May 6
6 33464534 Motor Deficits Coupled to Cerebellar and Striatal Alterations in Ube3am-/p+ Mice Modelling Angelman Syndrome Are Attenuated by Adenosine A2A Receptor Blockade. 2021 Jun 1
7 33511551 Adenosine A2A receptor and vascular response: role of soluble epoxide hydrolase, adenosine A1 receptor and angiotensin-II. 2021 May 2
8 33630907 Pulsed-electromagnetic-field induced osteoblast differentiation requires activation of genes downstream of adenosine receptors A2A and A3. 2021 1
9 33683190 CD39/CD73/A2a Adenosine Metabolic Pathway: Targets for Moxibustion in Treating DSS-Induced Ulcerative Colitis. 2021 2
10 33706537 Molecular Mechanisms of Adenosine Stress T1 Mapping. 2021 Mar 1
11 33737925 Evaluation of Combination Strategies for the A2AR Inhibitor AZD4635 Across Tumor Microenvironment Conditions via a Systems Pharmacology Model. 2021 2
12 33778007 Enhancing Extracellular Adenosine Levels Restores Barrier Function in Acute Lung Injury Through Expression of Focal Adhesion Proteins. 2021 1
13 33837202 Adenosine integrates light and sleep signalling for the regulation of circadian timing in mice. 2021 Apr 9 1
14 33925516 Increased Extracellular Adenosine in Radiotherapy-Resistant Breast Cancer Cells Enhances Tumor Progression through A2AR-Akt-β-Catenin Signaling. 2021 Apr 27 3
15 33973110 Adenosine A2A receptor null chondrocyte transcriptome resembles that of human osteoarthritic chondrocytes. 2021 Sep 4
16 34050151 CRISPR/Cas9 mediated deletion of the adenosine A2A receptor enhances CAR T cell efficacy. 2021 May 28 2
17 34073488 Dual Actions of A2A and A3 Adenosine Receptor Ligand Prevents Obstruction-Induced Kidney Fibrosis in Mice. 2021 May 26 1
18 34224862 Increased ATP release and CD73-mediated adenosine A2A receptor activation mediate convulsion-associated neuronal damage and hippocampal dysfunction. 2021 Sep 2
19 34310936 Adenosine A2A receptor neurons in the olfactory bulb mediate odor-guided behaviors in mice. 2021 Oct 1 2
20 34473957 Sepsis expands a CD39+ plasmablast population that promotes immunosuppression via adenosine-mediated inhibition of macrophage antimicrobial activity. 2021 Sep 14 3
21 34544837 Selective Manipulation of G-Protein γ7 Subunit in Mice Provides New Insights into Striatal Control of Motor Behavior. 2021 Nov 3 2
22 34783558 Structure-Based Design of Dual-Acting Compounds Targeting Adenosine A2A Receptor and Histone Deacetylase as Novel Tumor Immunotherapeutic Agents. 2021 Nov 25 2
23 31707092 Caffeine prevents neurodegeneration and behavioral alterations in a mice model of agitated depression. 2020 Mar 2 1
24 31786982 Adenosine 2A Receptor Activation Contributes to Ang II-Induced Aortic Remodeling by Promoting Macrophage Retention. 2020 Jan 3
25 31953314 Adenosine Signaling Is Prognostic for Cancer Outcome and Has Predictive Utility for Immunotherapeutic Response. 2020 May 1 1
26 32052890 Adenosine A2A receptor (A2AR) stimulation enhances mitochondrial metabolism and mitigates reactive oxygen species-mediated mitochondrial injury. 2020 Apr 2
27 32284765 A2AR Antagonism with DZD2269 Augments Antitumor Efficacy of Irradiation in Murine Model. 2020 3
28 32311420 Hippocampal synaptic dysfunction in the SOD1G93A mouse model of Amyotrophic Lateral Sclerosis: Reversal by adenosine A2AR blockade. 2020 Jul 1
29 32394183 Adenosine A2A Receptors in Bone Marrow-Derived Cells Attenuate Cognitive Impairment in Mice After Chronic Hypoperfusion White Matter Injury. 2020 Oct 2
30 32409420 Conversion of ATP to adenosine by CD39 and CD73 in multiple myeloma can be successfully targeted together with adenosine receptor A2A blockade. 2020 May 1
31 32488862 Concomitant blockade of A2AR and CTLA-4 by siRNA-loaded polyethylene glycol-chitosan-alginate nanoparticles synergistically enhances antitumor T-cell responses. 2020 Dec 1
32 32553948 Silencing adenosine A2a receptor enhances dendritic cell-based cancer immunotherapy. 2020 Oct 2
33 32727810 Small molecule AZD4635 inhibitor of A2AR signaling rescues immune cell function including CD103+ dendritic cells enhancing anti-tumor immunity. 2020 Jul 1
34 32778777 Intraarticular injection of liposomal adenosine reduces cartilage damage in established murine and rat models of osteoarthritis. 2020 Aug 10 4
35 32781414 Rethinking the adenosine-A2AR checkpoint: implications for enhancing anti-tumor immunotherapy. 2020 Aug 2
36 32798727 Impairment of adenosinergic system in Rett syndrome: Novel therapeutic target to boost BDNF signalling. 2020 Nov 2
37 33025424 Caffeine has a dual influence on NMDA receptor-mediated glutamatergic transmission at the hippocampus. 2020 Dec 1
38 33031409 Therapeutic effects of adenosine in high flow 21% oxygen aereosol in patients with Covid19-pneumonia. 2020 1
39 33049319 Adenosine A2A receptors format long-term depression and memory strategies in a mouse model of Angelman syndrome. 2020 Dec 1
40 33390888 Caffeine and Parkinson's Disease: Multiple Benefits and Emerging Mechanisms. 2020 1
41 30249343 Adenosine receptor activation in the Th17 autoimmune responses of experimental autoimmune uveitis. 2019 May 1
42 30336152 Enhancing endogenous adenosine A2A receptor signaling induces slow-wave sleep without affecting body temperature and cardiovascular function. 2019 Jan 4
43 30578680 Chronic adenosine A2A receptor blockade induces locomotor sensitization and potentiates striatal LTD IN GPR37-deficient mice. 2019 Mar 3
44 30645771 Tenofovir Causes Bone Loss via Decreased Bone Formation and Increased Bone Resorption, Which Can Be Counteracted by Dipyridamole in Mice. 2019 May 1
45 30690114 Extracellular adenosine and slow-wave sleep are increased after ablation of nucleus accumbens core astrocytes and neurons in mice. 2019 Mar 1
46 30971294 CD73 promotes hepatocellular carcinoma progression and metastasis via activating PI3K/AKT signaling by inducing Rap1-mediated membrane localization of P110β and predicts poor prognosis. 2019 Apr 11 2
47 31248747 Exercise exerts an anxiolytic effect against repeated restraint stress through 5-HT2A-mediated suppression of the adenosine A2A receptor in the basolateral amygdala. 2019 Oct 2
48 31315945 Indirect Medium Spiny Neurons in the Dorsomedial Striatum Regulate Ethanol-Containing Conditioned Reward Seeking. 2019 Sep 4 1
49 31394204 Synaptic and memory dysfunction in a β-amyloid model of early Alzheimer's disease depends on increased formation of ATP-derived extracellular adenosine. 2019 Dec 1
50 31409667 Novel Adenosine Analog, N6-(4-Hydroxybenzyl)-Adenosine, Dampens Alcohol Drinking and Seeking Behaviors. 2019 Nov 3