Adenosine Triphosphate

checkpoint kinase 2 ; Homo sapiens







15 Article(s)
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1 33762357 DNA Damage Response Protein CHK2 Regulates Metabolism in Liver Cancer. 2021 Jun 1 2
2 31343838 Divergent Synthesis and Evaluation of the in vitro Cytotoxicity Profiles of 3,4-Ethylenedioxythiophenyl-2-propen-1-one Analogues. 2019 Aug 6 3
3 26437226 Identification of novel, in vivo active Chk1 inhibitors utilizing structure guided drug design. 2015 Nov 3 1
4 23776527 Fragment-based screening maps inhibitor interactions in the ATP-binding site of checkpoint kinase 2. 2013 1
5 23058106 Benzimidazole inhibitors of the protein kinase CHK2: clarification of the binding mode by flexible side chain docking and protein-ligand crystallography. 2012 Nov 15 3
6 21186793 Structure-based design of potent and selective 2-(quinazolin-2-yl)phenol inhibitors of checkpoint kinase 2. 2011 Jan 27 2
7 21239475 CCT241533 is a potent and selective inhibitor of CHK2 that potentiates the cytotoxicity of PARP inhibitors. 2011 Jan 15 1
8 20022510 Identification and characterisation of 2-aminopyridine inhibitors of checkpoint kinase 2. 2010 Jan 15 1
9 20962588 Cdc5 blocks in vivo Rad53 activity, but not in situ activity (ISA). 2010 Nov 1 1
10 19207465 Molecular docking and 3D QSAR studies of Chk2 inhibitors. 2009 Mar 1
11 19741151 Cellular inhibition of checkpoint kinase 2 (Chk2) and potentiation of camptothecins and radiation by the novel Chk2 inhibitor PV1019 [7-nitro-1H-indole-2-carboxylic acid {4-[1-(guanidinohydrazone)-ethyl]-phenyl}-amide]. 2009 Dec 4
12 17035018 Identification of novel, selective and potent Chk2 inhibitors. 2007 Jan 1 1
13 17616632 Identification of a Bis-guanylhydrazone [4,4'-Diacetyldiphenylurea-bis(guanylhydrazone); NSC 109555] as a novel chemotype for inhibition of Chk2 kinase. 2007 Oct 4
14 15771432 Checkpoint kinase inhibitors: SAR and radioprotective properties of a series of 2-arylbenzimidazoles. 2005 Mar 24 1
15 16150728 DNA damage regulates Chk2 association with chromatin. 2005 Nov 11 2