Etoposide

checkpoint kinase 2 ; Homo sapiens







15 Article(s)
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1 34208028 Etoposide Triggers Cellular Senescence by Inducing Multiple Centrosomes and Primary Cilia in Adrenocortical Tumor Cells. 2021 Jun 11 4
2 34960710 ATM-Dependent Phosphorylation of Hepatitis B Core Protein in Response to Genotoxic Stress. 2021 Dec 5 2
3 30516086 Destabilization of the MiniChromosome Maintenance (MCM) complex modulates the cellular response to DNA double strand breaks. 2018 1
4 26751770 CHK2 stability is regulated by the E3 ubiquitin ligase SIAH2. 2016 Aug 18 1
5 26986476 PTEN enhances G2/M arrest in etoposide-treated MCF‑7 cells through activation of the ATM pathway. 2016 May 1
6 25088203 BMI1 attenuates etoposide-induced G2/M checkpoints via reducing ATM activation. 2015 Jun 4 3
7 26690546 Chloroquine alleviates etoposide-induced centrosome amplification by inhibiting CDK2 in adrenocortical tumor cells. 2015 Dec 21 2
8 24915421 A novel small molecule hybrid of vorinostat and DACA displays anticancer activity against human hormone-refractory metastatic prostate cancer through dual inhibition of histone deacetylase and topoisomerase I. 2014 Aug 1 1
9 23000346 Signaling crosstalk of FHIT, CHK2 and p38 in etoposide induced growth inhibition in MCF-7 cells. 2013 Jan 7
10 23089312 TIS21(/BTG2/PC3) accelerates the repair of DNA double strand breaks by enhancing Mre11 methylation and blocking damage signal transfer to the Chk2(T68)-p53(S20) pathway. 2012 Dec 1 1
11 20637859 Both ERK1 and ERK2 kinases promote G2/M arrest in etoposide-treated MCF7 cells by facilitating ATM activation. 2010 Nov 1
12 21037108 Selective inhibition of histone deacetylase 6 (HDAC6) induces DNA damage and sensitizes transformed cells to anticancer agents. 2010 Nov 16 1
13 12717439 Chk2 activates E2F-1 in response to DNA damage. 2003 May 3
14 11096068 The plant isoflavenoid genistein activates p53 and Chk2 in an ATM-dependent manner. 2001 Feb 16 1
15 11741320 Etoposide and adriamycin but not genistein can activate the checkpoint kinase Chk2 independently of ATM/ATR. 2001 Dec 21 3