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19549748 | Lack of regulation of 11beta-hydroxysteroid dehydrogenase type 1 during short-term manipulation of GH in patients with hypopituitarism. | 2009 Sep |
1 |
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19571556 | Regulatory effect of common promoter polymorphisms on the expression of the 11beta-hydroxysteroid dehydrogenase type 1 gene. | 2009 |
1 |
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19651257 | HSD11B1 polymorphisms predicted bone mineral density and fracture risk in postmenopausal women without a clinically apparent hypercortisolemia. | 2009 Dec |
1 |
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19837912 | 11Beta-hydroxysteroid dehydrogenase type 1 and its role in the hypothalamus-pituitary-adrenal axis, metabolic syndrome, and inflammation. | 2009 Dec |
1 |
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1 |
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17963039 | 11beta-HSD1, inflammation, metabolic disease and age-related cognitive (dys)function. | 2008 Apr |
1 |
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17986636 | Modulation of 11beta-hydroxysteroid dehydrogenase (11betaHSD) activity biomarkers and pharmacokinetics of PF-00915275, a selective 11betaHSD1 inhibitor. | 2008 Feb |
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18420938 | Local and systemic glucocorticoid metabolism in inflammatory arthritis. | 2008 Sep |
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18434359 | A novel selective 11beta-hydroxysteroid dehydrogenase type 1 inhibitor prevents human adipogenesis. | 2008 May |
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18769825 | [Possible pathogenetic role of 11 beta-hydroxysteroid dehydrogenase type 1 (11betaHSD1) gene polymorphisms in arterial hypertension]. | 2008 Jun |
1 |
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19292355 | 11beta-hydroxysteroid dehydrogenase type 1 expression in periprosthetic osteolysis. | 2008 Jun |
1 |
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19918113 | Role of calcitriol and cortisol on human adipocyte proliferation and oxidative and inflammatory stress: a microarray study. | 2008 |
1 |
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17200165 | Inhibition of 11beta-hydroxysteroid dehydrogenase type 1 activity in vivo limits glucocorticoid exposure to human adipose tissue and decreases lipolysis. | 2007 Mar |
2 |
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17343766 | Extra-adrenal regeneration of glucocorticoids by 11beta-hydroxysteroid dehydrogenase type 1: physiological regulator and pharmacological target for energy partitioning. | 2007 Feb |
2 |
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17467270 | Dehydroepiandrosterone 7alpha-hydroxylation in human tissues: possible interference with type 1 11beta-hydroxysteroid dehydrogenase-mediated processes. | 2007 May |
2 |
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17495191 | Omental 11beta-hydroxysteroid dehydrogenase 1 correlates with fat cell size independently of obesity. | 2007 May |
1 |
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17555498 | Rosiglitazone decreases 11beta-hydroxysteroid dehydrogenase type 1 in subcutaneous adipose tissue. | 2007 Sep |
1 |
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17584152 | Readjusting the glucocorticoid balance: an opportunity for modulators of 11beta-hydroxysteroid dehydrogenase type 1 activity? | 2007 Jun |
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17588937 | 11beta-Hydroxysteroid Dehydrogenase Type 1 Regulation by Intracellular Glucose 6-Phosphate Provides Evidence for a Novel Link between Glucose Metabolism and Hypothalamo-Pituitary-Adrenal Axis Function. | 2007 Sep 14 |
1 |
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17593901 | Type 2 diabetes and metabolic syndrome are associated with increased expression of 11beta-hydroxysteroid dehydrogenase 1 in obese subjects. | 2007 Dec |
1 |
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17593962 | Hexose-6-phosphate dehydrogenase modulates 11beta-hydroxysteroid dehydrogenase type 1-dependent metabolism of 7-keto- and 7beta-hydroxy-neurosteroids. | 2007 Jun 27 |
1 |
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17618751 | Simultaneously reduced gene expression of cortisol-activating and cortisol-inactivating enzymes in placentas of small-for-gestational-age neonates. | 2007 Jul |
2 |
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17624766 | 7alpha- and 7beta-hydroxy-epiandrosterone as substrates and inhibitors for the human 11beta-hydroxysteroid dehydrogenase type 1. | 2007 Jun-Jul |
1 |
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17761898 | PTGER1 and PTGER2 receptors mediate regulation of progesterone synthesis and type 1 11beta-hydroxysteroid dehydrogenase activity by prostaglandin E2 in human granulosa lutein cells. | 2007 Sep |
2 |
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17951535 | Role of glucocorticoid receptor and CCAAT/enhancer-binding protein alpha in the feed-forward induction of 11beta-hydroxysteroid dehydrogenase type 1 expression by cortisol in human amnion fibroblasts. | 2007 Nov |
4 |
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18054738 | Modulation of glucocorticoid action and the treatment of type-2 diabetes. | 2007 Dec |
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16469798 | Enhancement of cortisol-induced 11beta-hydroxysteroid dehydrogenase type 1 expression by interleukin 1beta in cultured human chorionic trophoblast cells. | 2006 May |
1 |
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16551740 | Genetic variation in 11beta-hydroxysteroid dehydrogenase type 1 predicts adrenal hyperandrogenism among lean women with polycystic ovary syndrome. | 2006 Jun |
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16636996 | Cell-based assay for screening 11beta-hydroxysteroid dehydrogenase inhibitors using liquid chromatography/tandem mass spectrometry detection. | 2006 |
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16759088 | The discovery of new 11beta-hydroxysteroid dehydrogenase type 1 inhibitors by common feature pharmacophore modeling and virtual screening. | 2006 Jun 15 |
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15513927 | Conformational flexibility in crystal structures of human 11beta-hydroxysteroid dehydrogenase type I provide insights into glucocorticoid interconversion and enzyme regulation. | 2005 Feb 11 |
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15934114 | Reduced capacity for the reactivation of glucocorticoids in rheumatoid arthritis synovial cells: possible role of the sympathetic nervous system? | 2005 Jun |
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15956339 | Hexose-6-phosphate dehydrogenase confers oxo-reductase activity upon 11 beta-hydroxysteroid dehydrogenase type 1. | 2005 Jun |
3 |
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16054388 | Steroid signalling in the ovarian surface epithelium. | 2005 Sep |
1 |
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16091483 | Genotypes at 11beta-hydroxysteroid dehydrogenase type 11B1 and hexose-6-phosphate dehydrogenase loci are not risk factors for apparent cortisone reductase deficiency in a large population-based sample. | 2005 Oct |
1 |
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16180992 | High-throughput screening of 11beta-hydroxysteroid dehydrogenase type 1 in scintillation proximity assay format. | 2005 Aug |
1 |
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14742837 | Regulation of 11beta-HSD genes in human adipose tissue: influence of central obesity and weight loss. | 2004 Jan |
2 |
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15152005 | Appropriate function of 11beta-hydroxysteroid dehydrogenase type 1 in the endoplasmic reticulum lumen is dependent on its N-terminal region sharing similar topological determinants with 50-kDa esterase. | 2004 Jul 23 |
1 |
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15181046 | Weight loss increases 11beta-hydroxysteroid dehydrogenase type 1 expression in human adipose tissue. | 2004 Jun |
1 |
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15356059 | Antiinflammatory steroid action in human ovarian surface epithelial cells. | 2004 Sep |
1 |
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15455200 | In the lipodystrophy associated with highly active antiretroviral therapy, pseudo-Cushing's syndrome is associated with increased regeneration of cortisol by 11beta-hydroxysteroid dehydrogenase type 1 in adipose tissue. | 2004 Oct |
1 |
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15525550 | 11beta-hydroxysteroid dehydrogenases: changing glucocorticoid action. | 2004 Dec |
1 |
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15536220 | Molecular screening of the 11beta-HSD1 gene in men characterized by the metabolic syndrome. | 2004 Oct |
1 |
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12519867 | Effects of the 11 beta-hydroxysteroid dehydrogenase inhibitor carbenoxolone on insulin sensitivity in men with type 2 diabetes. | 2003 Jan |
2 |
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12519881 | Modulation of 11 beta-hydroxysteroid dehydrogenase type 1 in mature human subcutaneous adipocytes by hypothalamic messengers. | 2003 Jan |
2 |
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12852864 | Alterations in human placental 11beta-hydroxysteroid dehydrogenase type 1 and 2 with gestational age and labour. | 2003 Aug |
1 |
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12858176 | Mutations in the genes encoding 11beta-hydroxysteroid dehydrogenase type 1 and hexose-6-phosphate dehydrogenase interact to cause cortisone reductase deficiency. | 2003 Aug |
2 |
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12881590 | Inhibition of 11beta-hydroxysteroid dehydrogenase type 1 lowers intraocular pressure in patients with ocular hypertension. | 2003 Jul |
1 |