Hydrocortisone

hydroxysteroid 11-beta dehydrogenase 1 ; Homo sapiens







184 Article(s)
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51 25934644 Saturated fatty acids in human visceral adipose tissue are associated with increased 11- β-hydroxysteroid-dehydrogenase type 1 expression. 2015 May 2 2
52 26056536 Association of HSD11B1 polymorphic variants and adipose tissue gene expression with metabolic syndrome, obesity and type 2 diabetes mellitus: a systematic review. 2015 1
53 26163245 The expression of 11β-hydroxysteroid dehydrogenase type 1 and 2 in nasal polyp-derived epithelial cells and its possible contribution to glucocorticoid activation in nasal polyp. 2015 Jul-Aug 2
54 26308294 Glucocorticoid Excess Increases Hepatic 11β-HSD-1 Activity in Humans: Implications in Steroid-Induced Diabetes. 2015 Nov 2
55 23025717 Auto-amplification of cortisol actions in human carotid atheroma is linked to arterial remodeling and stroke. 2014 Feb 2
56 24285685 Genetic polymorphisms in 11β-hydroxysteroid dehydrogenase type 1 correlate with the postdexamethasone cortisol levels and bone mineral density in patients evaluated for osteoporosis. 2014 Feb 2
57 24294985 Medicinal chemistry of inhibitors of 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1). 2014 Jun 12 1
58 24447082 Differential expression of 11β-hydroxysteroid dehydrogenase type 1 and 2 in mild and moderate/severe persistent allergic nasal mucosa and regulation of their expression by Th2 cytokines: asthma and rhinitis. 2014 Feb 1
59 24710966 Tissue-specific dysregulation of cortisol regeneration by 11βHSD1 in obesity: has it promised too much? 2014 Jun 1
60 24736562 Cortisol biosynthesis in the human ocular surface innate immune response. 2014 1
61 24743397 Tissue-specific dysregulation of 11β-hydroxysteroid dehydrogenase type 1 in overweight/obese women with polycystic ovary syndrome compared with weight-matched controls. 2014 Jul 1
62 24810847 Expression of 11β-hydroxysteroid dehydrogenase 1 and 2 in patients with chronic rhinosinusitis and their possible contribution to local glucocorticoid activation in sinus mucosa. 2014 Oct 1
63 24944027 The multifaceted mineralocorticoid receptor. 2014 Jul 1
64 25249770 Gender-dependent association of HSD11B1 single nucleotide polymorphisms with glucose and HDL-C levels. 2014 Sep 1
65 23132696 Novel H6PDH mutations in two girls with premature adrenarche: 'apparent' and 'true' CRD can be differentiated by urinary steroid profiling. 2013 Feb 1
66 23362866 Expression profiles of cortisol-inactivating enzyme, 11β-hydroxysteroid dehydrogenase-2, in human epidermal tumors and its role in keratinocyte proliferation. 2013 Feb 2
67 23363016 Ultraviolet radiation regulates cortisol activity in a waveband-dependent manner in human skin ex vivo. 2013 Mar 1
68 23678035 Ovarian 11β-hydroxysteroid dehydrogenase (11βHSD) activity is suppressed in women with anovulatory polycystic ovary syndrome (PCOS): apparent role for ovarian androgens. 2013 Aug 1
69 24022868 Dehydroepiandrosterone exerts antiglucocorticoid action on human preadipocyte proliferation, differentiation, and glucose uptake. 2013 Nov 1 1
70 24055708 11β-Hydroxysteroid dehydrogenase 1 contributes to the pro-inflammatory response of keratinocytes. 2013 Oct 18 1
71 24061267 A variant (rs932335) in the HSD11B1 gene is associated with colorectal cancer in a Chinese population. 2013 Nov 1
72 25436731 The role and regulation of 11β-hydroxysteroid dehydrogenase type 1 in obesity and the metabolic syndrome. 2013 Sep 1
73 22205698 Endometrial HSD11B1 and cortisol regeneration in the ovine uterus: effects of pregnancy, interferon tau, and prostaglandins. 2012 Apr 2
74 22310475 A gene variant of 11β-hydroxysteroid dehydrogenase type 1 is associated with obesity in children. 2012 Dec 1
75 22486586 Is there sufficient evidence to consider the use of 11β-hydroxysteroid dehydrogenase type 1 inhibition in children? 2012 Aug 1
76 22521153 Activated glucocorticoid and eicosanoid pathways in endometriosis. 2012 Jul 3
77 22606035 Identification of important chemical features of 11β-hydroxysteroid dehydrogenase type1 inhibitors: application of ligand based virtual screening and density functional theory. 2012 1
78 22719058 Expression of 11β-hydroxysteroid dehydrogenase enzymes in human osteosarcoma: potential role in pathogenesis and as targets for treatments. 2012 Aug 1
79 22863925 Benzofuran derivatives inhibit 11β-hydroxysteroid dehydrogenase type 1 activity in rat adipose tissue. 2012 1
80 23241228 Evidence for transcript-specific epigenetic regulation of glucocorticoid-stimulated skeletal muscle 11β-hydroxysteroid dehydrogenase-1 activity in type 2 diabetes. 2012 Dec 17 1
81 23304545 Differences in Expression, Content, and Activity of 11β-HSD1 in Adipose Tissue between Obese Men and Women. 2012 1
82 20739946 Localization, age- and site-dependent expression, and regulation of 11β-hydroxysteroid dehydrogenase type 1 in skin. 2011 Jan 2
83 21344493 Keratinocytes synthesize and activate cortisol. 2011 Jun 1
84 21453287 Hepatic reduction of the secondary bile acid 7-oxolithocholic acid is mediated by 11β-hydroxysteroid dehydrogenase 1. 2011 Jun 15 1
85 21544007 11β-Hydroxysteroid dehydrogenase type 1 activity in short small-for-GA children and in response to GH therapy. 2011 Aug 1
86 21565791 Identification of novel GH-regulated pathway of lipid metabolism in adipose tissue: a gene expression study in hypopituitary men. 2011 Jul 1
87 21966510 Substrate binding process and mechanistic functioning of type 1 11β-hydroxysteroid dehydrogenase from enhanced sampling methods. 2011 1
88 19882252 11β-Hydroxysteroid dehydrogenase type-2 and type-1 (11β-HSD2 and 11β-HSD1) and 5β-reductase activities in the pathogenia of essential hypertension. 2010 Feb 2
89 20015040 11beta-hydroxysteroid dehydrogenase type 1 inhibitors as promising therapeutic drugs for diabetes: status and development. 2010 1
90 20347978 Targeting the pre-receptor metabolism of cortisol as a novel therapy in obesity and diabetes. 2010 Oct 2
91 20410225 Testosterone stimulates adipose tissue 11beta-hydroxysteroid dehydrogenase type 1 expression in a depot-specific manner in children. 2010 Jul 4
92 20514603 Repeated measurements of 11β-HSD-1 activity in subcutaneous adipose tissue from lean, abdominally obese, and type 2 diabetes subjects--no change following a mixed meal. 2010 Oct 2
93 20631029 Glucocorticoids turn over slowly in human adipose tissue in vivo. 2010 Oct 1
94 18665910 Hepatic 11beta-HSD1 mRNA expression in fatty liver and nonalcoholic steatohepatitis. 2009 Apr 1
95 18716005 Glucocorticoid response elements and 11 beta-hydroxysteroid dehydrogenases in the regulation of endothelial nitric oxide synthase expression. 2009 Jan 1 1
96 18840637 Expression of 11beta-hydroxysteroid dehydrogenase type 1 in human fetal lung and regulation of its expression by interleukin-1beta and cortisol. 2009 Jan 1
97 19010388 Hexose-6-phosphate dehydrogenase modulates the effect of inhibitors and alternative substrates of 11beta-hydroxysteroid dehydrogenase 1. 2009 Mar 25 1
98 19167490 Epimerase activity of the human 11beta-hydroxysteroid dehydrogenase type 1 on 7-hydroxylated C19-steroids. 2009 Mar 1
99 19251840 Th2 cytokine-induced upregulation of 11beta-hydroxysteroid dehydrogenase-1 facilitates glucocorticoid suppression of proasthmatic airway smooth muscle function. 2009 May 2
100 19542736 Increased clearance of cortisol by 5beta-reductase in a subgroup of women with adrenal hyperandrogenism in polycystic ovary syndrome. 2009 Mar 1