| 1 |
34814007 | Regulation of 11β-HSD1 by GH/IGF-1 in key metabolic tissues may contribute to metabolic disease in GH deficient patients. | 2022 Feb |
2 |
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35014156 | Inhibition of 11β-Hydroxysteroid dehydrogenase-1 with AZD4017 in patients with nonalcoholic steatohepatitis or nonalcoholic fatty liver disease: A randomized, double-blind, placebo-controlled, phase II study. | 2022 May |
1 |
| 3 |
35537608 | Discovery of 1'-(1-phenylcyclopropane-carbonyl)-3H-spiro[isobenzofuran-1,3'-pyrrolidin]-3-one as a novel steroid mimetic scaffold for the potent and tissue-specific inhibition of 11β-HSD1 using a scaffold-hopping approach. | 2022 Aug 1 |
1 |
| 4 |
33236103 | Improved Urinary Cortisol Metabolome in Addison Disease: A Prospective Trial of Dual-Release Hydrocortisone. | 2021 Mar 8 |
1 |
| 5 |
33270115 | Effects of Obesity and Insulin on Tissue-Specific Recycling Between Cortisol and Cortisone in Men. | 2021 Mar 8 |
1 |
| 6 |
33466883 | Cortisol on Circadian Rhythm and Its Effect on Cardiovascular System. | 2021 Jan 14 |
1 |
| 7 |
33639236 | The rise in expression and activity of 11β-HSD1 in human mesenchymal progenitor cells induces adipogenesis through increased local cortisol synthesis. | 2021 Jun |
3 |
| 8 |
33640459 | Altered glucocorticoid metabolism in girls with central obesity. | 2021 May 1 |
1 |
| 9 |
33722534 | Addressing the role of 11β-hydroxysteroid dehydrogenase type 1 in the development of polycystic ovary syndrome and the putative therapeutic effects of its selective inhibition in a preclinical model. | 2021 Jun |
2 |
| 10 |
34143883 | An Open-label Phase I/IIa Clinical Trial of 11β-HSD1 Inhibitor for Cushing's Syndrome and Autonomous Cortisol Secretion. | 2021 Sep 27 |
2 |
| 11 |
34185432 | C/EBPδ drives key endocrine signals in the human amnion at parturition. | 2021 Jun |
1 |
| 12 |
34445315 | Novel 2-(Adamantan-1-ylamino)Thiazol-4(5H)-One Derivatives and Their Inhibitory Activity towards 11β-HSD1-Synthesis, Molecular Docking and In Vitro Studies. | 2021 Aug 10 |
1 |
| 13 |
34639470 | Association between Selected Polymorphisms rs12086634, rs846910, rs4844880, rs3753519 of 11β-Hydroxysteroid Dehydrogenase Type 1 (HSD11B1) and the Presence of Insulin Resistance in the Polish Population of People Living in Upper Silesia. | 2021 Sep 27 |
1 |
| 14 |
34651587 | Imaging brain cortisol regulation in PTSD with a target for 11β-hydroxysteroid dehydrogenase type 1. | 2021 Oct 15 |
2 |
| 15 |
34743342 | Evaluation of 11-β hydroxysteroid dehydrogenase type 1 in cutaneous fibroblasts cultures of psoriatic lesional skin before and after narrow band-UVB phototherapy. | 2021 Nov 7 |
2 |
| 16 |
30895878 | First in-human PET study and kinetic evaluation of [18F]AS2471907 for imaging 11β-hydroxysteroid dehydrogenase type 1. | 2020 Apr |
1 |
| 17 |
31664610 | Design, synthesis, molecular docking and in vitro evaluation of benzothiazole derivatives as 11β-hydroxysteroid dehydrogenase type 1 inhibitors. | 2020 Nov |
1 |
| 18 |
31704233 | Association of 11β-hydroxysteroid dehydrogenase type1 (HSD11b1) gene polymorphisms with outcome of antidepressant therapy and suicide attempts. | 2020 Mar 2 |
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| 19 |
31902257 | The upregulation of 11β-HSD1 in ovarian granulosa cells by cortisol and interleukin-1β in polycystic ovary syndrome. | 2020 Aug |
7 |
| 20 |
32306986 | Imbalanced cortisol concentrations in glycogen storage disease type I: evidence for a possible link between endocrine regulation and metabolic derangement. | 2020 Apr 19 |
1 |
| 21 |
32328292 | HSD11B1 is upregulated synergistically by IFNγ and TNFα and mediates TSG-6 expression in human UC-MSCs. | 2020 |
1 |
| 22 |
32333937 | 11β-hydroxysteroid dehydrogenase type 1 inhibitor use in human disease-a systematic review and narrative synthesis. | 2020 Jul |
2 |
| 23 |
32436946 | Perfluoroalkyl Substance Exposure Early In Pregnancy Was Negatively Associated With Late Pregnancy Cortisone Levels. | 2020 Aug 1 |
2 |
| 24 |
32523541 | Cortisol Regeneration in the Fetal Membranes, A Coincidental or Requisite Event in Human Parturition? | 2020 |
4 |
| 25 |
33036588 | The contribution of serum cortisone and glucocorticoid metabolites to detrimental bone health in patients receiving hydrocortisone therapy. | 2020 Oct 10 |
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| 26 |
33238679 | [Genetic expression differences of 11 beta-hydroxysteroid dehydrogenase in the bone microvascular endothelial cells derived from different regions of the human femoral head]. | 2020 Nov 24 |
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| 27 |
30689943 | A Novel 18F-Labeled Radioligand for Positron Emission Tomography Imaging of 11β-Hydroxysteroid Dehydrogenase (11β-HSD1): Synthesis and Preliminary Evaluation in Nonhuman Primates. | 2019 May 15 |
1 |
| 28 |
30774405 | Role of 11β HSD 1, rs12086634, and rs846910 single-nucleotide polymorphisms in metabolic-related skin diseases: a clinical, biochemical, and genetic study. | 2019 |
1 |
| 29 |
30796905 | Expression and activity of the cortisol-activating enzyme 11β-hydroxysteroid dehydrogenase type 1 is tissue and species-specific. | 2019 Apr 25 |
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| 30 |
31131948 | Involvement of STAT3 in the synergistic induction of 11β-HSD1 by SAA1 and cortisol in human amnion fibroblasts. | 2019 Aug |
5 |
| 31 |
31558916 | Interaction of HSD11B1 and H6PD polymorphisms in subjects with type 2 diabetes are protective factors against obesity: a cross-sectional study. | 2019 |
2 |
| 32 |
29385440 | 11β-HSD1 in Human Fetal Membranes as a Potential Therapeutic Target for Preterm Birth. | 2018 Jun 1 |
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| 33 |
29611097 | Increased cortisol metabolism in women with pregnancy-related hypertension. | 2018 Jul |
1 |
| 34 |
29975580 | DIFFERENTIAL REGULATION OF 11β-HYDROXYSTEROID DEHYDROGENASE TYPE 1 ACTIVITY IN PATIENTS WITH DIFFERING ETIOLOGIES OF HYPOPITUITARISM. | 2018 Oct 2 |
2 |
| 35 |
30086417 | Thiazolo[3,2-a]pyrimidin-5-one derivatives as a novel class of 11β-hydroxysteroid dehydrogenase inhibitors. | 2018 Dec |
2 |
| 36 |
30245006 | Design, synthesis, and biological evaluation of novel selective peptide inhibitors of 11β-hydroxysteroid dehydrogenase 1. | 2018 Oct 1 |
1 |
| 37 |
28366868 | Recent advances in the study of 11β-Hydroxysteroid dehydrogenase type 2 (11β-HSD2)Inhibitors. | 2017 Jun |
1 |
| 38 |
28680378 | Effects of Cellular 11β-hydroxysteroid Dehydrogenase 1 on LPS-induced Inflammatory Responses in Synovial Cell Line, SW982. | 2017 Jun |
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| 39 |
28735224 | Simultaneous quantification of cortisol and cortisone in urines from infants with packed-fiber solid-phase extraction coupled to HPLC-MS/MS. | 2017 Sep 1 |
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| 40 |
29047245 | 11β-Hydroxysteroid Dehydrogenase Type 1 Inhibition Attenuates the Adverse Effects of Glucocorticoids on Dermal Papilla Cells. | 2017 Nov |
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| 41 |
29484105 | Local cortisol activation is involved in EGF-induced immunosuppression. | 2017 |
2 |
| 42 |
26934392 | Local Regeneration of Cortisol by 11β-HSD1 Contributes to Insulin Resistance of the Granulosa Cells in PCOS. | 2016 May |
2 |
| 43 |
27288094 | Effect of PFOS on glucocorticoid-induced changes in human decidual stromal cells in the first trimester of pregnancy. | 2016 Aug |
1 |
| 44 |
27431412 | Local cortisol/corticosterone activation in skin physiology and pathology. | 2016 Oct |
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| 45 |
27533889 | Inhibition of Lysyl Oxidase by Cortisol Regeneration in Human Amnion: Implications for Rupture of Fetal Membranes. | 2016 Oct |
2 |
| 46 |
27697223 | Compartmentalized localization of 11β-HSD 1 and 2 at the feto-maternal interface in the first trimester of human pregnancy. | 2016 Oct |
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| 47 |
25196629 | Higher glucocorticoid secretion in the physiological range is associated with lower bone strength at the proximal radius in healthy children: importance of protein intake adjustment. | 2015 Feb |
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| 48 |
25303491 | 11β-hydroxysteroid dehydrogenase types 1 and 2 activity in subcutaneous adipose tissue in humans: implications in obesity and diabetes. | 2015 Jan |
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| 49 |
25393644 | 11β-Hydroxysteroid dehydrogenase activity in the brain does not contribute to systemic interconversion of cortisol and cortisone in healthy men. | 2015 Feb |
1 |
| 50 |
25812383 | [Current status of clinical development of novel anti-diabetic drugs]. | 2015 Mar |
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