Pyruvic Acid

pyruvate dehydrogenase kinase 1 ; Homo sapiens







14 Article(s)
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#Total Relationships
1 34488935 Drug evaluation based on phosphomimetic PDHA1 reveals the complexity of activity-related cell death in A549 non-small cell lung cancer cells. 2021 Nov 1
2 32705170 Inhibition of pyruvate dehydrogenase kinase‑1 by dicoumarol enhances the sensitivity of hepatocellular carcinoma cells to oxaliplatin via metabolic reprogramming. 2020 Sep 2
3 30700909 FOXK1 and FOXK2 regulate aerobic glycolysis. 2019 Feb 1
4 31198853 Resistance to anoikis in transcoelomic shedding: the role of glycolytic enzymes. 2019 Mar 1 1
5 29416012 ROS-independent ER stress-mediated NRF2 activation promotes warburg effect to maintain stemness-associated properties of cancer-initiating cells. 2018 Feb 7 1
6 29425506 Early TCR Signaling Induces Rapid Aerobic Glycolysis Enabling Distinct Acute T Cell Effector Functions. 2018 Feb 6 1
7 28230160 Global view of cognate kinase activation by the human pyruvate dehydrogenase complex. 2017 Feb 23 1
8 27189088 HIF-1α-PDK1 axis-induced active glycolysis plays an essential role in macrophage migratory capacity. 2016 May 18 1
9 24825347 Wnt signaling directs a metabolic program of glycolysis and angiogenesis in colon cancer. 2014 Jul 1 1
10 20957634 Anticancer drugs that target metabolism: Is dichloroacetate the new paradigm? 2011 Mar 1 1
11 17555402 Oxygen-dependent regulation of mitochondrial respiration by hypoxia-inducible factor 1. 2007 Jul 1 2
12 16517405 HIF-1-mediated expression of pyruvate dehydrogenase kinase: a metabolic switch required for cellular adaptation to hypoxia. 2006 Mar 1
13 16517406 HIF-1 mediates adaptation to hypoxia by actively downregulating mitochondrial oxygen consumption. 2006 Mar 1
14 15512796 R-lipoic acid inhibits mammalian pyruvate dehydrogenase kinase. 2004 Oct 2