Hydrogen Peroxide

mitogen-activated protein kinase kinase kinase 5 ; Homo sapiens







44 Article(s)
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1 35218032 Gamma-oryzanol protects human liver cell (L02) from hydrogen peroxide-induced oxidative damage through regulation of the MAPK/Nrf2 signaling pathways. 2022 Feb 25 1
2 34158609 Glutathione peroxidase-1 regulates ASK1-dependent apoptosis via interaction with TRAF2 in RIPK3-negative cancer cells. 2021 Jun 2
3 34209102 Prdx1 Interacts with ASK1 upon Exposure to H2O2 and Independently of a Scaffolding Protein. 2021 Jun 30 2
4 29138796 Reactive oxygen species induce injury of the intestinal epithelium during hyperoxia. 2018 Jan 1
5 29707240 Dual function of peroxiredoxin I in lipopolysaccharide-induced osteoblast apoptosis via reactive oxygen species and the apoptosis signal-regulating kinase 1 signaling pathway. 2018 1
6 26409120 Induced peroxidase and cytoprotective enzyme expressions support adaptation of HUVECs to sustain subsequent H2O2 exposure. 2016 Jan 1
7 26839109 Oxidative stress and premature senescence in corneal endothelium following penetrating keratoplasty in an animal model. 2016 Feb 2 1
8 26912789 Cross-talk between Arg methylation and Ser phosphorylation modulates apoptosis signal-regulating kinase 1 activation in endothelial cells. 2016 Apr 15 2
9 27221474 Glycogen synthase kinase-3β antagonizes ROS-induced hepatocellular carcinoma cell death through suppression of the apoptosis signal-regulating kinase 1. 2016 Jul 2
10 27387771 Intracellular labile iron determines H2O2-induced apoptotic signaling via sustained activation of ASK1/JNK-p38 axis. 2016 Aug 3
11 27600583 Oxidative Stress Impairs the Stimulatory Effect of S100 Proteins on Protein Phosphatase 5 Activity. 2016 Sep 1
12 26622762 Peroxiredoxin 1 suppresses apoptosis via regulation of the apoptosis signal-regulating kinase 1 signaling pathway in human oral leukoplakia. 2015 Sep 2
13 24448648 Roquin-2 promotes ubiquitin-mediated degradation of ASK1 to regulate stress responses. 2014 Jan 21 1
14 22997161 Aquaporin 1, Nox1, and Ask1 mediate oxidant-induced smooth muscle cell hypertrophy. 2013 Jan 1 1
15 23123190 Stress-induced nuclear import of apoptosis signal-regulating kinase 1 is mediated by karyopherin α2/β1 heterodimer. 2013 Mar 1
16 23443157 Probucol inhibits hydrogen peroxide to induce apoptosis of vascular smooth muscle cells. 2013 Apr 1
17 23569274 Notch1 modulates oxidative stress induced cell death through suppression of apoptosis signal-regulating kinase 1. 2013 Apr 23 1
18 22824861 Radiosensitization by 2-deoxy-D-glucose and 6-aminonicotinamide involves activation of redox sensitive ASK1-JNK/p38MAPK signaling in head and neck cancer cells. 2012 Oct 1 1
19 21725208 p34 (SEI-1) inhibits ROS-induced cell death through suppression of ASK1. 2011 Sep 1 2
20 19880523 Serine-threonine kinase receptor-associated protein inhibits apoptosis signal-regulating kinase 1 function through direct interaction. 2010 Jan 1 1
21 20213747 DJ-1 modulates the p38 mitogen-activated protein kinase pathway through physical interaction with apoptosis signal-regulating kinase 1. 2010 May 1
22 20674765 Protein phosphatase with EF-hand domains 2 (PPEF2) is a potent negative regulator of apoptosis signal regulating kinase-1 (ASK1). 2010 Nov 2
23 19306926 beta-Arrestins facilitate ubiquitin-dependent degradation of apoptosis signal-regulating kinase 1 (ASK1) and attenuate H2O2-induced apoptosis. 2009 Jul 2
24 19570911 REDOX reaction at ASK1-Cys250 is essential for activation of JNK and induction of apoptosis. 2009 Aug 2
25 17700517 G1 to S phase transition protein 1 induces apoptosis signal-regulating kinase 1 activation by dissociating 14-3-3 from ASK1. 2008 Feb 21 2
26 18501712 A novel function of peroxiredoxin 1 (Prx-1) in apoptosis signal-regulating kinase 1 (ASK1)-mediated signaling pathway. 2008 Jun 11 3
27 19069379 [Role of apoptosis signal-regulating kinase 1 (ASK 1)-mediated signaling pathway during ischemic retinal injury]. 2008 Nov 1
28 17258890 Granzyme B induction signalling pathway in acute myeloid leukemia cell lines stimulated by tumor necrosis factor alpha and Fas ligand. 2007 Jun 1
29 17456047 Regulation of apoptosis signal-regulating kinase 1 by protein phosphatase 2Cepsilon. 2007 Aug 1 6
30 17652454 Disulfide Bond-mediated multimerization of Ask1 and its reduction by thioredoxin-1 regulate H(2)O(2)-induced c-Jun NH(2)-terminal kinase activation and apoptosis. 2007 Oct 1
31 17724081 Thioredoxin and TRAF family proteins regulate reactive oxygen species-dependent activation of ASK1 through reciprocal modulation of the N-terminal homophilic interaction of ASK1. 2007 Dec 1
32 16827794 PP2C family members play key roles in regulation of cell survival and apoptosis. 2006 Jul 1
33 15755722 Protein kinase D specifically mediates apoptosis signal-regulating kinase 1-JNK signaling induced by H2O2 but not tumor necrosis factor. 2005 May 13 5
34 15782121 Hsp90-Akt phosphorylates ASK1 and inhibits ASK1-mediated apoptosis. 2005 Jun 2 5
35 14764578 Oxidant hypersensitivity of Fanconi anemia type C-deficient cells is dependent on a redox-regulated apoptotic pathway. 2004 Apr 16 4
36 15598880 The ASK1-MAP kinase cascades in mammalian stress response. 2004 Sep 2
37 14505347 Catalase, but not MnSOD, inhibits glucose deprivation-activated ASK1-MEK-MAPK signal transduction pathway and prevents relocalization of Daxx: hydrogen peroxide as a major second messenger of metabolic oxidative stress. 2003 Oct 1 2
38 14668614 Apoptosis signal-regulating kinase 1-mediated signaling pathway regulates hydrogen peroxide-induced apoptosis in human pulmonary vascular endothelial cells. 2003 Dec 3
39 11709494 Selenite suppresses hydrogen peroxide-induced cell apoptosis through inhibition of ASK1/JNK and activation of PI3-K/Akt pathways. 2002 Jan 3
40 11920685 Activation of apoptosis signal-regulating kinase 1 by the stress-induced activating phosphorylation of pre-formed oligomer. 2002 Apr 7
41 12089063 Thioredoxin promotes ASK1 ubiquitination and degradation to inhibit ASK1-mediated apoptosis in a redox activity-independent manner. 2002 Jun 28 1
42 11689443 Negative feedback regulation of ASK1 by protein phosphatase 5 (PP5) in response to oxidative stress. 2001 Nov 1 3
43 9564042 Mammalian thioredoxin is a direct inhibitor of apoptosis signal-regulating kinase (ASK) 1. 1998 May 1 1
44 9651337 Reactive oxygen species- and dimerization-induced activation of apoptosis signal-regulating kinase 1 in tumor necrosis factor-alpha signal transduction. 1998 Jul 10 3